排序方式: 共有363条查询结果,搜索用时 15 毫秒
361.
Alipour Shirin Wojciechowska Natalia Bujarska-Borkowska Barbara Kalemba Ewa Marzena 《Journal of plant research》2023,136(1):83-96
Journal of Plant Research - Norway maple and sycamore, two Acer genus species, have an important ecological value and different sensitivity to stressing factors being currently aggravated by... 相似文献
362.
Śledzińska Paulina Bebyn Marek Szczerba Ewelina Furtak Jacek Harat Maciej Olszewska Natalia Kamińska Katarzyna Kowalewski Janusz Lewandowska Marzena A. 《Molecular diagnosis & therapy》2022,26(6):699-713
Molecular Diagnosis & Therapy - The accurate detection of genetic variants such as single substitutions (IDH1/2, TERT), chromosomal abnormalities (CDKN2A, 1p/19q deletions, and EGFR... 相似文献
363.
Iwona Malicka Katarzyna Siewierska Bartosz Pula Christopher Kobierzycki Dominik Haus Urszula Paslawska Marek Cegielski Piotr Dziegiel Marzena Podhorska-Okolow Marek Wozniewski 《Experimental biology and medicine (Maywood, N.J.)》2015,240(11):1408-1415
The impact of physical activity on carcinogenesis has been demonstrated in many studies. Taking into account the discrepant results of physical exercise on the cell proliferation and apoptosis of breast cancer, we aimed to examine the impact of physical training on N-methyl-N-nitrosourea-(MNU)-induced mammary carcinogenesis. Fifty female rats were divided into four groups according to the intensity of physical activity they undertook. The number of developed tumors, tumor volume, and histopathological diagnoses were noted. Apoptosis and cell proliferation were studied by the number of TUNEL-positive and Ki-67-expressing cells. We demonstrated a statistically significant decrease in the tumor number between all trained groups and the control group. The results were most pronounced in the group with a moderate intensity of training. Moreover, we showed a decrease in tumor volume as training intensity increased, though the differences were not statistically significant. The mean number of TUNEL-positive cancer cells was significantly higher in the training groups than in the control group. These data suggest that physical training, especially of moderate intensity, may alleviate MNU-induced mammary carcinogenesis. The results could suggest that physical exercise-induced apoptosis may be a protective mechanism. 相似文献