排序方式: 共有98条查询结果,搜索用时 218 毫秒
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Sterba J Vancová M Rudenko N Golovchenko M Tremblay TL Kelly JF MacKenzie CR Logan SM Grubhoffer L 《Journal of bacteriology》2008,190(7):2619-2623
We investigated the presence of glycoproteins in Borrelia burgdorferi. We did not find any evidence for glycosylation of the major outer membrane proteins OspA and OspB or the structural flagellar proteins FlaB and FlaA. We suggest that glycoproteins present on the surface of B. burgdorferi may be tightly bound culture medium glycoproteins. 相似文献
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Magdalena Niedziałkowska Kris J. Hundertmark Bogumiła Jędrzejewska Krzysztof Niedziałkowski Vadim E. Sidorovich Marcin Górny Rauno Veeroja Erling J. Solberg Sauli Laaksonen Håkan Sand Vyacheslav A. Solovyev Maryna Shkvyria Juha Tiainen Innokentiy M. Okhlopkov Rimvydas Juškaitis Gundega Done Vadim A. Borodulin Evgenii A. Tulandin Włodzimierz Jędrzejewski 《Journal of Biogeography》2014,41(11):2173-2184
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Maryna Raskin M. Ann Easterbrooks Francine Jacobs Nathan E. Fosse Jessica L. Goldberg 《应用发育科学》2019,23(2):170-182
This paper examined heterogeneity in parents’ patterns of goal attainment following home visiting. Young mothers (n = 696) participating in a randomized controlled trial (RCT) evaluation of a statewide home visiting program were classified, using latent class analysis (LCA), according to their pattern of goal attainment (i.e., educational attainment, employment, parenting, personal functioning) two years postpartum. We explored direct and indirect (via social connectedness) associations between program participation and goal attainment. LCA revealed four classes: (a) High Education & Employment/High Parenting & Personal Functioning (n = 286, 41%); (b) High Education & Employment/Low Parenting & Personal Functioning (n = 212, 30%); (c) Low Education & Employment/Low Parenting & Personal Functioning (n = 71, 10%); and (d) Low Education & Employment/High Parenting & Personal Functioning (n = 127, 18%). Home visiting was not directly associated with class membership, but indirectly through social connectedness. This paper contributes to understanding home visiting impacts. 相似文献
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Nancy Costigliola Maryna T. Kapustina Gabriel E. Weinreb Zenon Rajfur Ken Jacobson 《Biophysical journal》2010,99(4):1053-1063
When microtubules are depolymerized in spreading cells, they experience morphological oscillations characterized by a period of about a minute, indicating that normal interactions between the microfilament and microtubule systems have been significantly altered. This experimental system provides a test bed for the development of both fine- and coarse-grained models of complex motile processes, but such models need to be adequately informed by experiment. Using criteria based on Fourier transform analysis, we detect spontaneous oscillations in spreading cells. However, their amplitude and tendency to operate at a single frequency are greatly enhanced by microtubule depolymerization. Knockdown of RhoA and addition of various inhibitors of the downstream effector of RhoA, Rho kinase, block oscillatory behavior. Inhibiting calcium fluxes from endoplasmic reticulum stores and from the extracellular medium does not significantly affect the ability of cells to oscillate, indicating that calcium plays a subordinate regulatory role compared to Rho. We characterized the dynamic structure of the oscillating cell by light, fluorescence, and electron microscopy, showing how oscillating cells are dynamically polarized in terms of their overall morphology, f-actin and phosphorylated myosin light chain distribution, and nuclear position and shape. Not only will these studies guide future experiments, they will also provide a framework for the development of refined mathematical models of the oscillatory process. 相似文献
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