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991.
Knowing how species’ traits relate to processes that underlie occupancy patterns such as colonisation and population persistence,
is important for our understanding of how species survive in fragmented and changing landscapes. We used automatic UV light-traps
to sample noctuid moths on two remote islands, and compared traits of island occupants with those of a species pool from mainland
southeast Sweden. Widely distributed species, generalist species, species with a long adult activity period and species active
late in the summer had higher probability of occupancy on the remote islands. The results were consistent between islands.
The traits of host plant specificity and species with an adult activity period during late summer remained robust and were
statistically significant after controlling for any possible phylogenetic bias. This indicates that species exhibiting those
traits survive better when habitat and climate changes. It is crucial to include our results in; (1) conservation planning,
e.g. when devising conservation measures in fragmented landscapes; (2) for predictions of future occupancy patterns; and (3)
ecosystem impact assessments, e.g. the importance of moths as pollinators, herbivores and being the functional link between
parasitoids, plants, consumers and predators. 相似文献
992.
Predicted climate change implies warmer weather and a higher frequency of extreme weather situations. The consequences of the warm July in 2003 was investigated in contrast to the cold July in 2004 in southern Sweden with focus on the dispersal rate of two species of burnet moths (Zygaenidae). During an extensive mark-release-recapture program in metapopulations of burnet moths substantial differences in inter habitat patch dispersal rates were observed. For two species of Zygaena it was 2.14 and 2.18 times higher during the warm year. Measured patch dispersal rate significantly declined towards the edges of the large study-area, suggesting that individuals disperse outside the study-area. No significant differences in dispersal rates were found between the two species studied. The dispersal rates were similar for both females and males, and no density dependent effects on dispersal or effects of amount of nectar rich flowers were found. Dispersal events appeared as distinct movements, often reaching several kilometres. We conclude that dispersal depend on climatic conditions. Exceptionally warm years may be especially important for survival of certain species in metapopulation systems and this may be crucial for the survival of populations during scenarios of climate change. 相似文献
993.
Climate change is occurring more rapidly in the Arctic than elsewhere, and is predicted to have a large impact on biodiversity,
since entire cold-adapted ecosystems are likely to disappear. Here, we highlight changes in the insect species richness and
community composition of wild bees, butterflies and moths over 60 years in an area situated above the tree limit (Padjelanta
National Park) in northern Sweden. Although there were changes in habitat availability, indicated by a significant decrease
in the area of a glacier (from 22 km2 in 1898 to 7.5 km2 in 2009), and an increase in the area of birch forest in the National Park, we nevertheless found relatively moderate changes
in the insect communities. Indeed, the observed number of species increased from 52 in 1944 to 64 in 2008. Remarkably, the
mean number of butterflies and moths per site, but not wild bee species, increased significantly. Among the species that were
recorded in both periods, the average altitude of 17 species had shifted downhill, 12 shifted uphill, and the altitude of
the remaining 17 had not changed. While alterations in community composition were greater at the highest altitudes, changes
in the insect community were smaller than expected, indeed much smaller than those reported from agricultural landscapes in
North-West Europe. Interestingly, our results suggest that lower alpine altitudes (600–800 m a.s.l.) have become colonized
by southern species, but also that high alpine areas (above 1,000 m a.s.l.) have recently become colonized by high alpine
species previously absent from these sites, likely as a result of increasing habitat availability. We conclude that wild bee,
butterfly, and moth communities in Arctic areas in northern Sweden are in flux, as a result of climate change and suggest
that increased attention must be given to conservation planning in cold areas. In addition, we propose that monitoring programs
should be established, because more pronounced climate-driven changes can be expected in the future. 相似文献
994.
Schank JR Goldstein AL Rowe KE King CE Marusich JA Wiley JL Carroll FI Thorsell A Heilig M 《Addiction biology》2012,17(3):634-647
The role of kappa-opioid receptors (KOR) in the regulation of alcohol-related behaviors is not completely understood. For example, alcohol consumption has been reported to increase following treatment with KOR antagonists in rats, but was decreased in mice with genetic deletion of KOR. Recent studies have further suggested that KOR antagonists may selectively decrease alcohol self-administration in rats following a history of dependence. We assessed the effects of the KOR antagonist JDTic on alcohol self-administration, reinstatement of alcohol seeking induced by alcohol-associated cues or stress, and acute alcohol withdrawal-induced anxiety ('hangover anxiety'). JDTic dose-dependently reversed hangover anxiety when given 48 hours prior to testing, a time interval corresponding to the previously demonstrated anxiolytic efficacy of this drug. In contrast, JDTic decreased alcohol self-administration and cue-induced reinstatement of alcohol seeking when administered 2 hours prior to testing, but not at longer pre-treatment times. For comparison, we determined that the prototypical KOR antagonist nor-binaltorphimine can suppress self-administration of alcohol at 2 hours pre-treatment time, mimicking our observations with JDTic. The effects of JDTic were behaviorally specific, as it had no effect on stress-induced reinstatement of alcohol seeking, self-administration of sucrose, or locomotor activity. Further, we demonstrate that at a 2 hours pre-treatment time JDTic antagonized the antinociceptive effects of the KOR agonist U50,488H but had no effect on morphine-induced behaviors. Our results provide additional evidence for the involvement of KOR in regulation of alcohol-related behaviors and provide support for KOR antagonists, including JDTic, to be evaluated as medications for alcoholism. 相似文献
995.
996.
Knoll A Higgins JD Seeliger K Reha SJ Dangel NJ Bauknecht M Schröpfer S Franklin FC Puchta H 《The Plant cell》2012,24(4):1448-1464
The human hereditary disease Fanconi anemia leads to severe symptoms, including developmental defects and breakdown of the hematopoietic system. It is caused by single mutations in the FANC genes, one of which encodes the DNA translocase FANCM (for Fanconi anemia complementation group M), which is required for the repair of DNA interstrand cross-links to ensure replication progression. We identified a homolog of FANCM in Arabidopsis thaliana that is not directly involved in the repair of DNA lesions but suppresses spontaneous somatic homologous recombination via a RecQ helicase (At-RECQ4A)-independent pathway. In addition, it is required for double-strand break-induced homologous recombination. The fertility of At-fancm mutant plants is compromised. Evidence suggests that during meiosis At-FANCM acts as antirecombinase to suppress ectopic recombination-dependent chromosome interactions, but this activity is antagonized by the ZMM pathway to enable the formation of interference-sensitive crossovers and chromosome synapsis. Surprisingly, mutation of At-FANCM overcomes the sterility phenotype of an At-MutS homolog4 mutant by apparently rescuing a proportion of crossover-designated recombination intermediates via a route that is likely At-MMS and UV sensitive81 dependent. However, this is insufficient to ensure the formation of an obligate crossover. Thus, At-FANCM is not only a safeguard for genome stability in somatic cells but is an important factor in the control of meiotic crossover formation. 相似文献
997.
M Suorsa S Järvi M Grieco M Nurmi M Pietrzykowska M Rantala S Kangasjärvi V Paakkarinen M Tikkanen S Jansson EM Aro 《The Plant cell》2012,24(7):2934-2948
In nature, plants are challenged by constantly changing light conditions. To reveal the molecular mechanisms behind acclimation to sometimes drastic and frequent changes in light intensity, we grew Arabidopsis thaliana under fluctuating light conditions, in which the low light periods were repeatedly interrupted with high light peaks. Such conditions had only marginal effect on photosystem II but induced damage to photosystem I (PSI), the damage being most severe during the early developmental stages. We showed that PROTON GRADIENT REGULATION5 (PGR5)-dependent regulation of electron transfer and proton motive force is crucial for protection of PSI against photodamage, which occurred particularly during the high light phases of fluctuating light cycles. Contrary to PGR5, the NAD(P)H dehydrogenase complex, which mediates cyclic electron flow around PSI, did not contribute to acclimation of the photosynthetic apparatus, particularly PSI, to rapidly changing light intensities. Likewise, the Arabidopsis pgr5 mutant exhibited a significantly higher mortality rate compared with the wild type under outdoor field conditions. This shows not only that regulation of PSI under natural growth conditions is crucial but also the importance of PGR5 in PSI protection. 相似文献
998.
999.
Regeniter A Kuhle J Baumann T Sollberger M Herdener M Kunze U Camuso MC Monsch AU 《Methods (San Diego, Calif.)》2012,56(4):494-499
We compared the performance of the Meso Scale Diagnostics electrochemiluminescence (MSD) multiplex assay for t-tau and p-tau(231), originally developed for measurement of brain cell extract and tissue cultures, with the established standard method, the Innogenetics ELISA for total and p-tau(181). The methods were also clinically evaluated with 120 samples from our mono center population. The established Innogenetics ELISA procedures have been well optimized to measure patient samples in the normal and pathological range. Compared to the MSD they were superior in the limit of detection for total as well as p-tau. The obtained reference values for our normal controls were in the upper third of the published studies. Innogenetics tau, Innogenetics p-tau(181) and MSD t-tau differentiated the Alzheimer's (n=44) and minimal impairment group (MCI, n=39) from normal controls (n=37), but the MCI group was not statistically different from the normal controls. The MSD multiplex assay measured t-tau adequately but p-tau(231) could not differentiate normal from pathological results in CSF due to the high limit of detection. Both procedures however, have to be further standardized and complemented by adequate internal and external quality control schemes to qualify for routine analysis in a medical laboratory. 相似文献
1000.
Stoldt S Wenzel D Hildenbeutel M Wurm CA Herrmann JM Jakobs S 《Molecular biology of the cell》2012,23(12):2292-2301
The Oxa1 protein is a well-conserved integral protein of the inner membrane of mitochondria. It mediates the insertion of both mitochondrial- and nuclear-encoded proteins from the matrix into the inner membrane. We investigated the distribution of budding yeast Oxa1 between the two subdomains of the contiguous inner membrane--the cristae membrane (CM) and the inner boundary membrane (IBM)--under different physiological conditions. We found that under fermentable growth conditions, Oxa1 is enriched in the IBM, whereas under nonfermentable (respiratory) growth conditions, it is predominantly localized in the CM. The enrichment of Oxa1 in the CM requires mitochondrial translation; similarly, deletion of the ribosome-binding domain of Oxa1 prevents an enrichment of Oxa1 in the CM. The predominant localization in the IBM under fermentable growth conditions is prevented by inhibiting mitochondrial protein import. Furthermore, overexpression of the nuclear-encoded Oxa1 substrate Mdl1 shifts the distribution of Oxa1 toward the IBM. Apparently, the availability of nuclear- and mitochondrial-encoded substrates influences the inner-membrane distribution of Oxa1. Our findings show that the distribution of Oxa1 within the inner membrane is dynamic and adapts to different physiological needs. 相似文献