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211.
Mobarra Naser Gholamalizadeh Hanieh Abdulhussein Kaed A. Raji Sara Taheri Asl Fatemeh Mirvahabi Mobina Sadat Rafiee Mahdi Pakzad Reza 《Molecular biology reports》2022,49(5):3657-3663
Molecular Biology Reports - This study explored the applicability of serum level and tissue expression of Ribonucleotide-diphosphate Reductase subunit M2 B (RRM2B) as reliable biomarkers for... 相似文献
212.
213.
Samaneh Samavat Khalil Karimzadeh Asl 《Archives Of Phytopathology And Plant Protection》2019,52(1-2):18-29
Recent epidemics of box (boxwood) blight caused by the fungus Calonectria pseudonaviculata in Hyrcanian forests led to the search for eco-friendly fungicides. Essential oils (EOs) of medicinal plants undoubtedly have been highlighted as a new therapeutic approach. In this study, EOs from Cuminum cyminum, Lavandula angustifolia, Thymus daenensis, Trachyspermum copticum and Hyssopus officinalis were evaluated for their inhibitory activities against C. pseudonaviculata Cy-08 in vitro. Quantitative and qualitative composition variations of the EOs were also analysed by GC–MS. Based on the high inhibitory efficacy and low related EC50, MFC and MIC values, T. copticum, L. angustifolia and Th. daenensis EOs can be mentioned as those providing extraordinary efficacy against Cy-08, respectively. Major chemical components of T. copticum, L. angustifolia and Th. daenensis EOs were thymol, linalyl acetate and thymol, respectively. Thymol and linalyl acetate may be the most effective compounds against C. pseudonaviculata. 相似文献
214.
Tayebe Aghaie Mir Hadi Jazayeri Mostafa Manian leila Khani Marjan Erfani Majid Rezayi Gordon A. Ferns Amir Avan 《Journal of cellular biochemistry》2019,120(3):2749-2755
Gold nanoparticles (GNs) have unique characteristics, for example, stability, biocompatibility, small dimensions, and low toxicity. Several clinical applications have been suggested for GNs, such as diagnosis, imaging, and drug delivery. GNs absorb infrared light, indicating their potential value for imaging. There is growing evidence showing the therapeutic application of GN for drug delivery because of their interaction with the blood-brain barrier and DNA, the latter being associated with their genotoxic effects. GN can also be stimulated to produce high local temperatures, indicating their potential value in photodynamic therapy in the treatment of tumors. The aim of the current review is to summarize the potential applications of GNs in the biomedical field, specifically in neurodegenerative diseases. 相似文献
215.
Uysal Nazan Kizildag Servet Yuce Zeynep Guvendi Guven Kandis Sevim Koc Basar Karakilic Aslı Camsari Ulas M. Ates Mehmet 《Biological trace element research》2019,187(1):128-136
Biological Trace Element Research - Magnesium is an element of great importance functioning because of its association with many cellular physiological functions. The magnesium content of foods is... 相似文献
216.
Abdik Ezgi Avşar Abdik Hüseyin Taşlı Pakize Neslihan Deniz Ayşen Aslı Hızlı Şahin Fikrettin 《Biological trace element research》2019,188(2):384-392
Biological Trace Element Research - Over the past years, adipose tissue has become an invaluable source of mesenchymal stem cells (MSCs) due to development of improved isolation methodologies. In a... 相似文献
217.
Hosseini Seyedeh Arezoo Tahmoorespur Mojtaba Sekhavati Mohammad Hadi Monhemi Hassan Nassiri Mohammadreza 《International journal of peptide research and therapeutics》2019,25(4):1459-1465
International Journal of Peptide Research and Therapeutics - One major issue in cancer immunotherapy is the large size of mAbs (150 kDa) which usually causes limitation in tumor... 相似文献
218.
Suriakarthiga Ganesan Maria L. Sosa Ponce Marjan Tavassoli Brittney N. Shabits Mark Mahadeo Elmar J. Prenner Mauricio R. Terebiznik Vanina Zaremberg 《Traffic (Copenhagen, Denmark)》2019,20(3):226-245
Diacylglycerol (DAG) is a key signaling lipid and intermediate in lipid metabolism. Our knowledge of DAG distribution and dynamics in cell membranes is limited. Using live‐cell fluorescence microscopy we investigated the localization of yeast cytosolic‐facing pools of DAG in response to conditions where lipid homeostasis and DAG levels were known to be altered. Two main pools were monitored over time using DAG sensors. One pool was associated with vacuolar membranes and the other localized to sites of polarized growth. Dynamic changes in DAG distribution were observed during resumption of growth from stationary phase, when DAG is used to support phospholipid synthesis for membrane proliferation. Vacuolar membranes experienced constant morphological changes displaying DAG enriched microdomains coexisting with liquid‐disordered areas demarcated by Vph1. Formation of these domains was dependent on triacylglycerol (TAG) lipolysis. DAG domains and puncta were closely connected to lipid droplets. Lack of conversion of DAG to phosphatidate in growth conditions dependent on TAG mobilization, led to the accumulation of DAG in a vacuolar‐associated compartment, impacting the polarized distribution of DAG at budding sites. DAG polarization was also regulated by phosphatidylserine synthesis/traffic and sphingolipid synthesis in the Golgi. 相似文献
219.
Recently, an increasing number of studies have shown that Lake Van—the biggest soda lake in the world—is polluted due to an increasing population. Studies have shown abnormalities in the Lake Van fish (Chalcalburnus tarichi), the sole fish species that inhabits the lake. Unlike the vitellogenic and mature oocytes in normal gonads, abnormal gonads show large amounts of connective tissue and young oocytes. In this study, metal levels (nickel [Ni], copper [Cu], cobalt [Co], iron [Fe], zinc [Zn], cadmium [Cd], lead [Pb], and manganese [Mn]) in the muscle, liver, gill, intestine, and gonad of Lake Van fish with normal and abnormal gonads were assessed. Further, the metal contents in the wastewater from the wastewater treatment facility situated near Lake Van in Van City were assessed. All the metal levels, except that of Zn, were high in the Lake Van environment (P?<?0.05). The highest metal content in the tissues was for Fe, while the lowest level was for Co. The Pb level was found to be very high in both fish groups. Cd was not found in the tissues of both fish groups. The levels of Fe, Cu, Pb, and Mn were not significant in the tissues of both normal and abnormal fish groups. Zn level was significantly high in the livers and gonads of fish with abnormal gonads, and Co level was significantly high only in the livers (P?<?0.05). Consequently, high levels of Zn in the liver and gonads and high levels of Co in the liver may be factors causing the abnormal gonads in the Lake Van fish. 相似文献
220.
T-helper 17 cell cytokines and interferon type I: partners in crime in systemic lupus erythematosus?
Zana Brkic Odilia BJ Corneth Cornelia G van Helden-Meeuwsen Radboud JEM Dolhain Naomi I Maria Sandra MJ Paulissen Nadine Davelaar Jan Piet van Hamburg Paul L van Daele Virgil A Dalm P Martin van Hagen Johanna MW Hazes Marjan A Versnel Erik Lubberts 《Arthritis research & therapy》2014,16(2):R62