The effect of feeding level on semen quantity and quality of breeding boars

An experiment was carried out to investigate the influence of feeding level on semen quantity and quality in breeding boars in two successive periods of 12 and 8 weeks. Forty-two Yorkshire boars (13 months old) were fed for 12 weeks ad libitum (H=5.74 kg/day), a medium feeding level (M=3.62 kg/day) or a low feeding level (L=1.92 kg/day). After 8 weeks the number of ejaculated sperm cells for boars on treatment L was lower than for those on treatments H and M (P <0.05). In the last 2 weeks, the M and H boars ejaculated 46 and 69% more sperm cells, respectively, than the L boars. Differences between all three feeding levels were significant (P < 0.05). After this 12-week period the feeding level was altered for the H and the L boars. H boars were fed a low feeding level (HL) and L boars were fed the medium feeding level (LM). The medium-fed boars were kept at the same feeding level (MM). After 8 weeks in the second period, differences in the number of ejaculated sperm cells between the HL and MM boars and between the LM and MM boars were no longer significant (P >0.05). Throughout the experiment, no differences in the quality parameters, percentage of moving sperm cells in the ejaculate, vitality of the moving sperm cells and non-return percentage at 56 days were found between treatment groups.     

Solid-phase synthesis of peptidosulfonamide containing peptides derived from Leu-enkephalin

Using Boc or Fmoc-protected β-substituted aminoethanesulfonyl chlorides (2-substituted taurylchlorides) the solid-phase synthesis of dipeptidosulfonamides as well as peptidosulfonamide containing peptides derived from Leu-enkephalin is described. The binding activity of the peptidosulfonamide YGGFL derivatives is reported.