首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   131423篇
  免费   2892篇
  国内免费   900篇
  135215篇
  2023年   243篇
  2022年   551篇
  2021年   961篇
  2020年   552篇
  2019年   711篇
  2018年   12575篇
  2017年   11218篇
  2016年   8667篇
  2015年   2665篇
  2014年   2514篇
  2013年   3358篇
  2012年   7659篇
  2011年   15844篇
  2010年   13808篇
  2009年   9825篇
  2008年   12046篇
  2007年   13540篇
  2006年   2402篇
  2005年   2448篇
  2004年   2772篇
  2003年   2767篇
  2002年   2376篇
  2001年   577篇
  2000年   372篇
  1999年   338篇
  1998年   402篇
  1997年   287篇
  1996年   277篇
  1995年   243篇
  1994年   253篇
  1993年   265篇
  1992年   164篇
  1991年   191篇
  1990年   162篇
  1989年   119篇
  1988年   123篇
  1987年   109篇
  1986年   76篇
  1985年   98篇
  1984年   107篇
  1983年   96篇
  1982年   90篇
  1981年   82篇
  1980年   80篇
  1979年   75篇
  1978年   45篇
  1977年   50篇
  1973年   44篇
  1972年   277篇
  1971年   300篇
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
991.
Micro- and nanometallic structures that exhibit extraordinary optical transmission (EOT) have attracted much attention for their potential applications in photonic devices. However, most existing reports have only discussed EOT at one specific wavelength, which limits its use in multi-wavelength applications. Here, we experimentally demonstrate EOT at multiple wavelengths through an asymmetric corrugated thin silver film due to simultaneous excitation of multiple plasmonic resonances at both interfaces. A unique method that applies single-pulse nanosecond laser interference lithography is introduced to produce the silver grating, which shows high quality over large area. At oblique incidence, each EOT peak is observed to split into two peaks oppositely shifted towards higher and lower frequencies. At some specific angles of incidence, overlap of these shifted peaks gives rise to distorted transmission spectra. Our method may find applications involving multiple wavelengths such as multi-wavelength bandpass filters, anti-Stokes Raman scattering spectroscopy, enhanced four-wave mixing, and so on.  相似文献   
992.
We theoretically investigated an enhancement of the magneto-optical Faraday rotations along with large transmittance in two multilayer structures. The shifts of the Faraday rotation peaks are more obvious than the transmittance peaks when the grating period is changed, which is beneficial to acquire the large Faraday rotation and transmittance. The Faraday rotation of tri-layer system is five times larger than the bilayer system, and the Faraday resonance peak can be mediated by changing the refractive index or thickness of the additional nonmagnetic dielectric layer (NDL) layer. These results are important for applications in highly integrated optoelectronic and magneto-optical devices.  相似文献   
993.
994.
995.
Stilbenes are a class of phenolic metabolites found in various edible plants, such as grapevine, berries and peanuts. Their bioactivitiy and their potential benefits for human health have been the subject of several studies. Among all identified stilbenes, resveratrol has been particularly studied and results from literature showed that it presents several biological activities, including antioxidant, anti-inflammatory and antiproliferative effects. Likewise, some researches focused on other stilbenes and highlighted similar biological activity for those compounds. However, stilbenes present a high diversity in their phenolic structures (various chemical substituents and polymerization) which is a determining factor of their absorption and metabolism rates. Consequently, this could affect the effectiveness of stilbenes in vivo. In this context, an evaluation of the bioavailability and metabolism of stilbenes is necessary to move forward with pharmacological and clinical studies. Hence, this review aims to present recently obtained data and results concerning stilbenes sources and bioavailability, as a contribution to the valorization of the role of dietary stilbenes in the human diet.  相似文献   
996.
997.
Growth factors and extracellular matrix (ECM) proteins are involved in wound healing. Human dermal fibroblasts secrete wound-healing mediators in culture medium known as dermal fibroblast conditioned medium (DFCM). However, the composition and concentration of the secreted proteins differ with culture conditions and environmental factors. We cultured human skin fibroblasts in vitro using serum-free keratinocyte-specific media (EpiLife? Medium [KM1] and defined keratinocyte serum-free medium [KM2]) and serum-free fibroblast-specific medium (FM) to obtain DFCM-KM1, DFCM-KM2 and DFCM-FM, respectively. We identified and compared their proteomic profiles using bicinchoninic acid assay (BCA), 1-dimensional sodium dodecyl sulphate-polyacrylamide gel electrophoresis (1D SDS-PAGE), enzyme-linked immunosorbent assay (ELISA), matrix-assisted laser desorption ionisation-time-of-flight mass spectrometry (MALDI-TOF/TOF MS/MS) and liquid chromatography MS (LC-MS/MS). DFCM-KM1 and DFCM-KM2 had higher protein concentrations than DFCM-FM but not statistically significant. MALDI-TOF/TOF MS identified the presence of fibronectin, serotransferrin, serpin and serum albumin. LC-MS/MS and bioinformatics analysis identified 59, 46 and 58 secreted proteins in DFCM-KM1, DFCM-KM2 and DFCM-FM, respectively. The most significant biological processes identified in gene ontology were cellular process, metabolic process, growth and biological regulation. STRING® analysis showed that most secretory proteins in the DFCMs were associated with biological processes (e.g. wound healing and ECM organisation), molecular function (e.g. ECM binding) and cellular component (e.g. extracellular space). ELISA confirmed the presence of fibronectin and collagen in the DFCMs. In conclusion, DFCM secretory proteins are involved in cell adhesion, attachment, proliferation and migration, which were demonstrated to have potential wound-healing effects by in vitro and in vivo studies.  相似文献   
998.
999.
1000.
In the present work, a constitutive model for articular cartilage is proposed in finite elasto-viscoplasticity. For simplification, articular cartilage is supposed to be a typical composite composed of a soft basis and a fiber assembly. The stress tensor and free energy function are hence accordingly divided into two components. The high nonlinear stress-strain response is assumed to be mainly related to the fiber assembly and described by an exponential-type hypoelastic relation. Ratcheting is considered according to the viscoplasticity, the evolution rule of which is deduced from the dissipative inequality by the co-directionality hypotheses. Then, the capability of the proposed model is validated by comparing its predictions with related experimental observations. Results show that the ratcheting behavior and stress-strain hysteresis loops are reasonably captured by the proposed model.  相似文献   
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号