全文获取类型
收费全文 | 5075篇 |
免费 | 222篇 |
国内免费 | 4篇 |
出版年
2022年 | 38篇 |
2021年 | 84篇 |
2020年 | 48篇 |
2019年 | 58篇 |
2018年 | 141篇 |
2017年 | 110篇 |
2016年 | 143篇 |
2015年 | 200篇 |
2014年 | 243篇 |
2013年 | 304篇 |
2012年 | 324篇 |
2011年 | 318篇 |
2010年 | 224篇 |
2009年 | 166篇 |
2008年 | 242篇 |
2007年 | 229篇 |
2006年 | 230篇 |
2005年 | 199篇 |
2004年 | 165篇 |
2003年 | 158篇 |
2002年 | 146篇 |
2001年 | 70篇 |
2000年 | 41篇 |
1999年 | 45篇 |
1998年 | 43篇 |
1997年 | 33篇 |
1996年 | 45篇 |
1995年 | 43篇 |
1994年 | 32篇 |
1993年 | 40篇 |
1992年 | 40篇 |
1991年 | 40篇 |
1990年 | 32篇 |
1989年 | 38篇 |
1988年 | 34篇 |
1987年 | 37篇 |
1986年 | 41篇 |
1985年 | 46篇 |
1984年 | 51篇 |
1983年 | 47篇 |
1982年 | 34篇 |
1981年 | 38篇 |
1980年 | 37篇 |
1979年 | 59篇 |
1978年 | 40篇 |
1975年 | 40篇 |
1974年 | 38篇 |
1973年 | 36篇 |
1969年 | 32篇 |
1966年 | 33篇 |
排序方式: 共有5301条查询结果,搜索用时 31 毫秒
171.
13beta-Ethyl-3-methoxy-17beta-ol-8,14-seco-1,3,5(10),8-gonatetraen-14-one (IIIa) was isolated and its participation in the well-known acidic cyclization process was established. 相似文献
172.
Antisera (B10.129×A)F1 anti-P and (B10×A)F1 anti-B10.P contain antibodies that define, in the PVP hemagglutination test, an antigen originally described as G or H-2.7. Of the independentH-2 haplotypes, the H-2.7 antigen is present inf, j, k, p, ands. In addition, the antisera also contain a weak cytotoxic antibody, distinct from anti-H-2.7. The cytotoxic antibody reacts with antigens controlled by theK orI regions. The hemagglutinating H-2.7 antibody does not have cytotoxic activity. The genetic determinant coding for antigen H-2.7 can be mapped into the chromosomal segment between theS andD regions. The H-2.7 antigen thus serves as a marker for a new region of theH-2 complex. The locus coding for antigen H-2.7 is designatedH-2 G and the correspondingH-2 regionG. The H-2.7 antigen has a tissue distribution distinct from that of the H-2 antigens controlled by theK orD regions. So far it could be detected primarily on erythrocytes. 相似文献
173.
Added free fatty acids inhibit oxidation of glycerol 3-phosphate, succinate and NADH in brown-adipose tissue mitochondria from 10-day-old rats. The most pronounced is the inhibitory effect of glycerol 3-phosphate cytochrome c reductase (GP-cyto. c reductase). Contrary to other reductases, GP-cyto. c reductase activity of freshly isolated mitochondria is already inhibited by the fraction of endogenous free fatty acids. Both added and endogenous free fatty acids inhibition of GP-cyto. c reductase is fully reversible by the removal of free fatty acids by bovine serum albumine treatment. The inhibition of GP-cyto. c reductase is of strictly non-competitive type. The most inhibitory are unsaturated long-chain free fatty acids-oleic and linoleic acid. Results are discussed with regards to the regulatory importance of free fatty acids in brown-adiposetissue during intensive non-shivering thermogenesis. 相似文献
174.
175.
Steroidal compounds have been utilized as carriers and for modification of physico-chemical properties of model biologically active secondary alcohols - juvenoids. Juvenoids are juvenile hormone analogues - environmentally safe insecticides, possessing significant biological activity towards different arthropods groups in focus on insect pest species. Structure modification of juvenoids plays important role to control the rate of liberation and decomposition of juvenoid in digestive system and can also play important role in the mode of action towards selected insect. This study presents an approach to the synthesis of steroidal monomers and dimers carrying one and two molecules of a juvenoid in their structures. The prepared compounds were tested for their inhibition activity on reproduction of the blowfly Neobellieria (Sarcophaga) bullata. These steroid-juvenoid conjugates showed promising possibilities in synthesis of new unique biochemical insecticides. Preliminary biological test results of prepared compounds are presented. 相似文献
176.
Jan Benes Hana Tomankova Martina Novakova Zdeněk Rohan Richard Kvetnansky Jaromir Myslivecek 《Cellular and molecular neurobiology》2013,33(4):503-511
Glucocorticoids act via glucocorticoid receptors (GR), typically localized in the cytosol (cGR). Rapid action is probably mediated via membrane receptors (mGR). In corticotropin-releasing hormone knockouts (CRH-KO), basal plasma glucocorticoid levels do differ from wild type levels (WT), but are approximately ten times lower during exposure to immobilization stress (IMMO) in comparison to WT. We tested the following hypotheses: (1) the mice lung tissue GR basal numbers would not be changed in CRH-KO (because of similar glucocorticoid levels), (2) the number of GR would be changed in WT but not in KO during short (30, 90, and 120 min) IMMO (because of higher increase of glucocorticoid levels in WT). The basal levels of cGR were not changed in CRH-KO (compared to WT), while mGR were significantly lower (62 %) in CRH-KO. In WT, there was the only decrease (to 32 %) in cGR after 120 min when we also found an increase in mGR in WT (to 201 %). In CRH-KO, IMMO caused gradual decrease in cGR (to 52 % after 30 min, to 46 % after 90 min, and to 32 % after 120 min). In CRH-KO, the only increase in mGR appeared already at 30 min of IMMO. These data suggest, on the contrary to our hypotheses, that CRH-KO are more susceptible to GR changes in early phases of stress. 相似文献
177.
J. Podpěra 《Plant Systematics and Evolution》1900,50(1):11-13
Ohne Zusammenfassung 相似文献
178.
179.
180.