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161.
Prado Valentina Cinelli Marco Ter Haar Sterre F. Ravikumar Dwarakanath Heijungs Reinout Guinée Jeroen Seager Thomas P. 《The International Journal of Life Cycle Assessment》2020,25(12):2393-2406
The International Journal of Life Cycle Assessment - Weighting in life cycle assessment (LCA) incorporates stakeholder preferences in the decision-making process of comparative LCAs. Research... 相似文献
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Ilse Storch Johannes Penner Thomas Asbeck Marco Basile Jürgen Bauhus Veronika Braunisch Carsten F. Dormann Julian Frey Stefanie Grtner Marc Hanewinkel Barbara Koch Alexandra‐Maria Klein Thomas Kuss Michael Pregernig Patrick Pyttel Albert Reif Michael Scherer‐Lorenzen Gernot Segelbacher Ulrich Schraml Michael Staab Georg Winkel Rasoul Yousefpour 《Ecology and evolution》2020,10(3):1489-1509
Retention forestry, which retains a portion of the original stand at the time of harvesting to maintain continuity of structural and compositional diversity, has been originally developed to mitigate the impacts of clear‐cutting. Retention of habitat trees and deadwood has since become common practice also in continuous‐cover forests of Central Europe. While the use of retention in these forests is plausible, the evidence base for its application is lacking, trade‐offs have not been quantified, it is not clear what support it receives from forest owners and other stakeholders and how it is best integrated into forest management practices. The Research Training Group ConFoBi (Conservation of Forest Biodiversity in Multiple‐use Landscapes of Central Europe) focusses on the effectiveness of retention forestry, combining ecological studies on forest biodiversity with social and economic studies of biodiversity conservation across multiple spatial scales. The aim of ConFoBi is to assess whether and how structural retention measures are appropriate for the conservation of forest biodiversity in uneven‐aged and selectively harvested continuous‐cover forests of temperate Europe. The study design is based on a pool of 135 plots (1 ha) distributed along gradients of forest connectivity and structure. The main objectives are (a) to investigate the effects of structural elements and landscape context on multiple taxa, including different trophic and functional groups, to evaluate the effectiveness of retention practices for biodiversity conservation; (b) to analyze how forest biodiversity conservation is perceived and practiced, and what costs and benefits it creates; and (c) to identify how biodiversity conservation can be effectively integrated in multi‐functional forest management. ConFoBi will quantify retention levels required across the landscape, as well as the socio‐economic prerequisites for their implementation by forest owners and managers. ConFoBi's research results will provide an evidence base for integrating biodiversity conservation into forest management in temperate forests. 相似文献
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168.
Integrated requirement of non‐specific and sequence‐specific DNA binding in Myc‐driven transcription
169.
Terzin Marko Paletta Maria Grazia Matterson Kenan Coppari Martina Bavestrello Giorgio Abbiati Marco Bo Marzia Costantini Federica 《Coral reefs (Online)》2021,40(4):1391-1391
Coral Reefs - A correction to this paper has been published: https://doi.org/10.1007/s00338-021-02120-y 相似文献
170.
Nicola Chiarelli Nicoletta Zoppi Marco Ritelli Marina Venturini Daniele Capitanio Cecilia Gelfi Marina Colombi 《生物化学与生物物理学报:疾病的分子基础》2021,1867(4):166051
Hypermobile Ehlers-Danlos syndrome (hEDS), mainly characterized by generalized joint hypermobility and its complications, minor skin changes, and apparently segregating with an autosomal dominant pattern, is still without a known molecular basis. Hence, its diagnosis is only clinical based on a strict set of criteria defined in the revised EDS nosology. Moreover, the hEDS phenotypic spectrum is wide-ranging and comprises multiple associated signs and symptoms shared with other heritable or acquired connective tissue disorders and chronic inflammatory diseases. In this complex scenario, we previously demonstrated that hEDS patients' skin fibroblasts show phenotypic features of myofibroblasts, widespread extracellular matrix (ECM) disarray, perturbation of ECM-cell contacts, and dysregulated expression of genes involved in connective tissue architecture and related to inflammatory and pain responses. Herein, the cellular proteome of 6 hEDS dermal myofibroblasts was compared to that of 12 control fibroblasts to deepen the knowledge on mechanisms involved in the disease pathogenesis. Qualitative and quantitative differences were assessed based on top-down and bottom-up approaches and some differentially expressed proteins were proofed by biochemical analyses. Proteomics disclosed the differential expression of proteins principally implicated in cytoskeleton organization, energy metabolism and redox balance, proteostasis, and intracellular trafficking. Our findings offer a comprehensive view of dysregulated protein networks and related pathways likely associated with the hEDS pathophysiology. The present results can be regarded as a starting point for future in-depth investigations aimed to decipher the functional impact of potential bioactive molecules for the development of targeted management and therapies. 相似文献