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排序方式: 共有159条查询结果,搜索用时 15 毫秒
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Aurélie?Najm Beno?t?Le?Goff Carl?Orr Rogier?Thurlings Juan?D.?Ca?ete Frances?Humby Stefano?Alivernini Antonio?Manzo S?ren?Andreas?Just Vasco?C.?Rom?o Veit?Krenn Ulf?Müller-Ladner Olga?Addimanda Sander?W.?Tas Maria?Stoenoiu Laurent?Meric?de?Bellefon Patrick?Durez Vibeke?Strand Mihir?D.?Wechalekar Joao?E.?Fonseca Bernard?Lauwerys Ursula?Fearon Douglas?J.?Veale 《Arthritis research & therapy》2018,20(1):282
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Localized cell death in Drosophila imaginal wing disc epithelium caused by the mutation apterous-blot 总被引:1,自引:0,他引:1
Drosophila melanogaster carrying the mutation apterous-blot have blistered wings. Trypan blue stains a patch of dead cells localized to the wing pouch of imaginal discs and the same area shows acid phosphatase (AcPase) activity suggesting that the cell death is lysosomal. Autophagic vacuoles and other secondary lysosomes show AcPase activity within the disc epithelium and enzyme activity is found in fragments of dead cells which have been extruded basally. The cell death, although extensive and confined to the presumptive wing region, does not result in loss of adult structures. 相似文献
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Silvio Matassa Pascal Boeckx Jos Boere Jan Willem Erisman Miao Guo Raffaele Manzo Francis Meerburg Stefano Papirio Ilje Pikaar Korneel Rabaey Diederik Rousseau Jerald Schnoor Peter Smith Erik Smolders Stefan Wuertz Willy Verstraete 《Microbial biotechnology》2023,16(1):15-27
Nitrogen is the most crucial element in the production of nutritious feeds and foods. The production of reactive nitrogen by means of fossil fuel has thus far been able to guarantee the protein supply for the world population. Yet, the production and massive use of fertilizer nitrogen constitute a major threat in terms of environmental health and sustainability. It is crucial to promote consumer acceptance and awareness towards proteins produced by highly effective microorganisms, and their potential to replace proteins obtained with poor nitrogen efficiencies from plants and animals. The fact that reactive fertilizer nitrogen, produced by the Haber Bosch process, consumes a significant amount of fossil fuel worldwide is of concern. Moreover, recently, the prices of fossil fuels have increased the cost of reactive nitrogen by a factor of 3 to 5 times, while international policies are fostering the transition towards a more sustainable agro-ecology by reducing mineral fertilizers inputs and increasing organic farming. The combination of these pressures and challenges opens opportunities to use the reactive nitrogen nutrient more carefully. Time has come to effectively recover used nitrogen from secondary resources and to upgrade it to a legal status of fertilizer. Organic nitrogen is a slow-release fertilizer, it has a factor of 2.5 or higher economic value per unit nitrogen as fertilizer and thus adequate technologies to produce it, for instance by implementing photobiological processes, are promising. Finally, it appears wise to start the integration in our overall feed and food supply chains of the exceptional potential of biological nitrogen fixation. Nitrogen produced by the nitrogenase enzyme, either in the soil or in novel biotechnology reactor systems, deserves to have a ‘renaissance’ in the context of planetary governance in general and the increasing number of people who desire to be fed in a sustainable way in particular. 相似文献
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