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591.
Srinivas Ganta Meghna Talekar Amit Singh Timothy P. Coleman Mansoor M. Amiji 《AAPS PharmSciTech》2014,15(3):694-708
Nanoemulsion dosage form serves as a vehicle for the delivery of active pharmaceutical ingredients and has attracted great attention in drug delivery and pharmacotherapy. In particular, nanoemulsions act as an excellent vehicle for poorly aqueous soluble drugs, which are otherwise difficult to formulate in conventional dosage forms. Nanoemulsions are submicron emulsions composed of generally regarded as safe grade excipients. Particle size at the nanoscale and larger surface area lead to some very interesting physical properties that can be exploited to overcome anatomical and physiological barriers associated in drug delivery to the complex diseases such as cancer. Along these lines, nanoemulsions have been engineered with specific attributes such as size, surface charge, prolonged blood circulation, target specific binding ability, and imaging capability. These attributes can be tuned to assist in delivering drug/imaging agents to the specific site of interest, based on active and passive targeting mechanisms. This review focuses on the current state of nanoemulsions in the translational research and its role in targeted cancer therapy. In addition, the production, physico-chemical characterization, and regulatory aspects of nanoemulsion are addressed. 相似文献
592.
593.
Idnan Muhammad Mansoor Sajid Khawar Muhammad Babar Javid Arshad Hussain Ali Imran Muhammad Ullah Arif 《Molecular biology reports》2022,49(3):1791-1797
Molecular Biology Reports - The lack of morphological differentiation among chiropteran species and cryptic speciation impedes species identification. DNA-based approaches help species... 相似文献
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595.
M. Shahul Hameed 《Hydrobiologia》1976,51(1):39-42
A new species ofAnuretes collected from the gills ofDiagramma crassispinum Day at Cape Comorin, India, is described in detail. The carapace of the three females obtained was folded ventrally likeHermilius on the gill filaments. 相似文献
596.
M. Shahul Hameed 《Hydrobiologia》1976,50(2):161-165
A new species of Lepeophtheirus collected from Plotosus anguillaris (Bloch) by the author is described in detail. All the related species of the genus are compared with Lepeophtheirus anguilli sp. nov. 相似文献
597.
Younis B. M. Heikal A. M. Hameed Mohamed Farhat O. Obayya S. S. A. 《Plasmonics (Norwell, Mass.)》2017,12(5):1529-1535
Plasmonics - In this paper, the coupling characteristics of a dual-core hybrid plasmonic liquid crystal photonic crystal fiber (PCF) is proposed and analyzed using full-vectorial finite-difference... 相似文献
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599.
Manganese-doped cerium oxide nanocomposite as a therapeutic agent for MCF-7 adenocarcinoma cell line
M. Atif Seemab Iqbal M. Fakhar-e-Alam Qaisar Mansoor K.S. Alimgeer Amanullah Fatehmulla Atif Hanif Nafeesah Yaqub W.A. Farooq Shafiq Ahmad Hijaz Ahmad Yu-ming Chu 《Saudi Journal of Biological Sciences》2021,28(2):1233-1238
The preparation of a manganese-doped cerium oxide (Mn:CeO2) nanocomposite via hydrothermal route is described. Cubic fluorite structure of single phase was exhibited by studying structural analysis through x-ray diffraction (XRD) technique and morphological analysis was conducted by scanning electron microscope. Surface analytic technique of energy dispersive x-ray spectroscopy (EDX) was conducted to analyze the relative amount of any impurity and doping. Structural changes due to manganese doping such as increment in production of vacancies of oxygen within crystal of cerium oxide, and reduction in size of crystallite and constant of lattice was observed in our research study. Moreover, the Mn:CeO2 nanocomposite demonstrates differential cytotoxicity against MCF-7 adenocarcinoma cell line, which renders it a promising candidate for targeted cancer therapy. The anti-tumorous activity of the cerium oxide nanocomposite was significantly enhanced with doping of manganese, which is directly linked with the generation of highly reactive oxygen facets. The experimental results are supported by a mathematical model that confirms a confidence level of 95%. This research has paved the way for many utilities in therapeutics and magnetic resonance imaging diagnostics through new observations, and hence verified their math model. 相似文献
600.
Shahzad Ali Gul Hameed Ahsan Muhammad Wang Depeng Fahad Shah 《Journal of Plant Growth Regulation》2023,42(2):989-1005
Journal of Plant Growth Regulation - A shortage of water acutely restricts maize plant development, which ultimately limits maize production. The identification of the potential genotypes under... 相似文献