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91.
The stability and the associated thermodynamic parameters of the binary and the ternary complexes of trivalent Am, Cm, and Eu with IDA and with EDTA + IDA, were determined by using a solvent extraction technique for aqueous solutions of I = 6.60 m (NaClO4) at temperatures of 0-60 °C. The endothermic enthalpy and the positive entropy reflect the significant effect of dehydration in the formation of these complexes at high ionic strength. TRLFS and NMR (1H and 13C) data helped to establish the structure of the ternary complexes in solution. In the ternary complex M(EDTA)(IDA)3−, EDTA binds via four carboxylates and two nitrogens, and IDA via two carboxylates and one nitrogen to the central Eu3+. 相似文献
92.
Park PH McMullen MR Huang H Thakur V Nagy LE 《The Journal of biological chemistry》2007,282(30):21695-21703
Adiponectin is an adipokine with potent anti-inflammatory properties. However, the mechanisms by which adiponectin suppresses macrophage function are not well understood. Treatment of RAW264.7 macrophages with adiponectin for 18 h decreased lipopolysaccharide (LPS)-stimulated tumor necrosis factor-alpha (TNF-alpha) production. Here we demonstrate that globular adiponectin (gAcrp) initially increased TNF-alpha expression in RAW264.7 macrophages; this TNF-alpha then contributed to increased expression of interleukin-10, which in turn was required for the development of tolerance to subsequent LPS exposure. gAcrp-mediated increases in TNF-alpha mRNA accumulation were associated with increased TNF-alpha promoter activity. gAcrp increased the DNA binding activity of both Egr-1 and NFkappaB; mutation of either the Egr-1 or NFkappaB binding sites in the TNF-alpha promoter decreased gAcrp-stimulated promoter activity. Further, co-transfection with either dominant negative Egr-1 or the IkappaB super-repressor prevented gAcrp-stimulated TNF-alpha promoter activity. gAcrp also increased Egr-1 promoter activity, mRNA accumulation, and DNA binding activity. Inhibition of ERK1/2 with U0126 potently suppressed gAcrp-stimulated Egr-1 promoter activity, as well as TNF-alpha promoter activity. In summary, these data demonstrate that adiponectin initially increases TNF-alpha production by macrophages via ERK1/2-->Egr-1 and NFkappaB-dependent mechanisms; these increases in TNF-alpha in turn lead to increased expression of interleukin-10 and an eventual dampening of LPS-mediated cytokine production in macrophages. 相似文献
93.
Alkalophilic bacterial consortium developed by continuous enrichment in the chemostat in presence of 4-chlorosalicylic acid
as sole source of carbon and energy contained six bacterial strains, Micrococcus luteus (csa101), Deinococcus radiothilus (csa102), csa103 (Burkholderia gladioli), Alloiococcus otilis (csa104), Micrococcus diversus (csa105), Micrococcus luteus (csa106), identified by the Biolog test method. The strains were tested for utilization of organic compounds in which one
of the strains (csa101) had higher potency to utilize dibenzofuran (DF) as sole carbon and energy source identified as Serratia marcescens on the basis of 16S rDNA. The degradation of DF by bacterial strain proceeded through an oxidative route as indicated by
2,2′3-trihydroxybiphenyl, 2-hydroxy-6-(2-hydroxyphenyl)-6-oxo-2,4-hexadienoic acid, salicylic acid, and catechol, which was
identified by gas chromatography–mass spectrometry. 相似文献
94.
AFD-Net: Apple Foliar Disease multi classification using deep learning on plant pathology dataset 总被引:2,自引:0,他引:2
Yadav Anju Thakur Udit Saxena Rahul Pal Vipin Bhateja Vikrant Lin Jerry Chun-Wei 《Plant and Soil》2022,477(1-2):595-611
Plant and Soil - Plant diseases significantly affect the crop, so their identification is very important. Correct identification of these diseases is crucial for establishing a good disease control... 相似文献
95.
Neurochemical Research - Cerebral ischemia is one of the most devastating brain injuries and a primary cause of acquired and persistent disability worldwide. Despite ongoing therapeutic... 相似文献
96.
Khan Heena Singh Thakur Gurjeet Dahiya Randhir Singh Abdel-Daim Mohamed M. 《Neurochemical research》2022,47(7):1853-1864
Neurochemical Research - Lipoic acid (α-LA) (1,2-dithiolane3-pentanoic acid (C8H14O2S2) is also called thioctic acid with an oxidized (disulfide, LA) and a reduced (di-thiol: dihydro-lipoic... 相似文献
97.
Patidar Preeti Bhayal Mamta Hajela Sumati Hajela Krishnan 《Journal of plant biochemistry and biotechnology.》2022,31(4):961-964
Journal of Plant Biochemistry and Biotechnology - A glycosylated heat stable trypsin chymotrypsin inhibitor was isolated from Cyamopsis tetragonoloba seeds. It is being reported for the first time... 相似文献
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