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91.
92.
Golovchenko AV Dobrovol'skaia TG Maksimova IA Terekhova VA Zviagintsev DG Trofimov SIa 《Mikrobiologiia》2000,69(4):453-464
General regularities in the structure of the microbial communities of southern taiga soil ecosystems and taxonomic differences between the microbial communities of soils with different hydrothermal characteristics are discussed with reference to the main types of soils of the Central State Forest Biosphere Reserve. 相似文献
93.
94.
Morozova OV Maksimova TG Popova RV Martsinkevich ON Bakhvalova VN 《Molekuliarnaia biologiia》2001,35(1):157-162
Bacteria were isolated from the nasopharynx of BALB/c mice and electroporated with pUR290(NS1)2 containing two copies of tick-borne encephalitis virus (TBEV) strain Sofjin NS1 under the control of the lac promoter. The plasmid persisted in transformants for at least ten passages. The NS1 gene expression was detected in Gram-negative enterobacteria via immunoblotting with monoclonal antibodies against TBEV nonstructural glycoprotein NS1. Recombinant NS1 was detected in bacterial cells and in the culture medium. Intranasal immunization with recombinant bacteria activated production of antibodies against NS1 in serum of BALB/c mice. The humoral immune response to NS1 failed to protect immunized mice from a TBEV challenge. 相似文献
95.
Changes in protoporphyrin conformation, partial pressures of O2 and CO2, and the mechanisms responsible for regulation of pCa and pH in erythrocytes were studied in essential hypertension (EH). Changes in protoporphyrin conformation in EH were accompanied by a decrease in the partial pressure of O2 and an increase in the partial pressure of CO2. This was associated with increased activities of Na+/H+-exchange and Ca2+-dependent K+-channels and with a decreased activity of Ca2+-ATPase. The changes in protoporphyrin conformation in EH are suggested to decrease the efficiency of O2 metabolism in hemoglobin and increase the values of intracellular pCa and pH of erythrocytes. 相似文献
96.
L L Klimenko Iu A Gryzunov L P Kudriashova A A Turna G N Matveev O V Protasova I A Maksimova M N Komarova V F Fokin 《Biofizika》1999,44(2):372-377
Neuroimmune interactions in systemic rheumatic diseases were studied. The state of the central nervous system was assessed from the parameters of constant brain potentials, and the state of the immune system, from a complex of immunobiochemical parameters. The highest multiple correlation coefficients were revealed between the immunobiochemical parameters and the parameters of the constant brain potential, which characterize linear and standard deviations of potentials in temporal zones from potentials at other points of recording. The results are discussed in terms of structural and functional integration of the immune and nervous systems. 相似文献
97.
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99.
L L Klimenko Iu A Gryzunov L P Kudriashova A A Turna G N Matveev O V Protasova I A Maksimova M N Komarova V F Fokin O V Protasova I A Maksimova M N Komarova V F Fokin 《Biofizika》1999,44(2):368-371
The data obtained upon examination of patients with systemic rheumatic diseases were analyzed by the methods of multiple regression and step-by-step discriminant analysis. Is was shown that the activity of autoimmune process correlates with the parameters of distribution of constant potential level in the brain of each patient, irrespective of diagnosis. The scatter of potential values was the most important predictor of activity. An increase in the activity of the autoimmune process correlated with a decrease in the scatter of potential values at recording points; the cerebral cortex became equipotential. 相似文献
100.
N M Maksimova N L Sukhorukova G I Kostiuchenko N B Mikha?lova D I Demina 《Zhurnal mikrobiologii, epidemiologii, i immunobiologii》1987,(8):36-40
The studies demonstrated the immunological and epidemiological effectiveness of a single injection of adsorbed diphtheria-tetanus toxoid with reduced antigen content for adults: intense antidiphtheria immunity in 92.3% of the vaccinees 1-3 months and in 94.5% of the vaccinees 1 year after the injection. This immunity remained sufficiently intense for 3 years (the term of observation). The geometric mean of antitoxic titers was 0.84 I. U./ml. The highest intensity of immunity appearing after the injection was observed in persons aged 18-20 years who showed the highest antitoxic titers (exceeding 0.5 I. U./ml) in 100% of cases, the lowest intensity was registered in the age group of 30-39 years; in 14.2% of these vaccinees antitoxic titers were below the protective level. In other age groups (40-49 years, 50 years and over) the intensity of immunity was high. The geometric mean of the titers of diphtheria antitoxin were 1.2 I. U./ml and 2.1 I. U./ml respectively. In none of the foci under study the spread of the manifest forms of the disease was observed. 相似文献