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101.
Ultrasonographic determinations of the thyroid gland volumes and measurement of the blood plasma content of thyroxin and triiodothyronine were carried out in 1176 apparently healthy residents of the Magadan oblast, all those examined being divided by sex, age, and the adaptation time in the North. Special attention was given to the thyroid system parameters of the aborigines 17 to 40 years old living in the urban area and not involved in the traditional life style. The indigenous population of the Extreme North and migrants were shown to have marked functional adaptive hyperplasia of the thyroid gland and diffuse goiter in 15% of cases. The size of the thyroid gland and the level of the thyroid hormones in the aboriginal population are within the average European range. Diffuse goiter manifestations in males virtually do not occur; in women, the incidence does not exceed 5%. The assumption is advanced as to the formation in aborigines of the northern hypothyroid phenotype providing for the sustained optimal level of the thyroid system functioning without an increase in the thyroid volume. 相似文献
102.
103.
Changes in the membrane-associated Ca2+ concentration and viscosity of the plasmatic membrane of P- and R-cells segmented ganglia of medicinal leech upon a variation of extracellular serotonin concentration were investigated. It is shown that the transmission of rhythmic excitation from P- to R-cells is due to the formation of the serotonin-dependent synapse and affects the distribution of the membrane-associated Ca2+ and intracellular processes controlling the viscosity of the membrane. 相似文献
104.
I. V. Maksimov R. R. Abizgil’dina L. I. Pusenkova 《Applied Biochemistry and Microbiology》2011,47(4):333-345
The review analyses data on physiological and biochemical influence of rhizospheric and endophytic plant growth promoting
rhizobacteria (PGPR) on induced the mechanisms of resistance of plants and the possibility of their using in agricultural
for to protect crop from pathogens and phytophages. Resistance of plants promoted by PGPR due to their endosymbiotic interrelationships
is directly achieved by producing peptide antibiotics and hydrolases of chitin and glucan and also because plants form their
own system of induced resistance, accompanied by changes in the balance of defensive proteins, phytohormones, and pro-/antioxidant
status. 相似文献
105.
M. A. Gubina L. A. Girgol’kau V. N. Babenko L. D. Damba V. N. Maksimov M. I. Voevoda 《Russian Journal of Genetics》2013,49(7):751-764
An analysis of mtDNA polymorphism in eight populations of aboriginal residents (N = 519) of the Far East has been performed. The majority of haplogroups revealed in the examined groups were of East Eurasian origin. Haplogroup D was revealed in seven populations and its frequency varied from 2.8% in Koryaks to 28.3% and 28.9% in Nanaians and Evenks, respectively. Chukchi and Koryak populations, which belong to the same language family, exhibited haplogroup G, which has the same motive and indicates the genetic kinship of both populations. The presence of East Eurasian haplogroups A and D with a strong predominance of haplogroup A in Chukchi indicates the closer relationship of this population both with Asian and Canadian Eskimos and northern Atapasks on the other side of Bering Strait. The high level of genetic variability was revealed in populations belonging to the Tungus-Manjur group. The high frequency of east Eurasian haplogroups in Nanaians could result from close historical associations with Siberian Evenks. 相似文献
106.
Evgeny N. Dobrov Nikolai A. Nikitin Ekaterina A. Trifonova Evgenia Yu. Parshina Valentin V. Makarov George V. Maksimov 《Journal of biomolecular structure & dynamics》2013,31(5):701-708
Conversion of the rod-like tobacco mosaic virus (TMV) virions into “ball-like particles” by thermal denaturation at 90–98?°C had been described by R.G. Hart in 1956. We have reported recently that spherical particles (SPs) generated by thermal denaturation of TMV at 94–98?°C were highly stable, RNA-free, and water-insoluble. The SPs were uniform in shape but varied widely in size (53–800?nm), which depended on the virus concentration. Here, we describe some structural characteristics of SPs using circular dichroism, fluorescence spectroscopy, and Raman spectroscopy. It was found that the structure of SPs protein differs strongly from that of the native TMV and is characterized by coat protein subunits transition from mainly (about 50%) α-helical structure to a structure with low content of α-helices and a significant fraction of β-sheets. The SPs demonstrate strong reaction with thioflavin T suggesting the formation of amyloid-like structures. 相似文献
107.
L. G. Yarullina N. B. Troshina E. A. Cherepanova E. A. Zaikina I. V. Maksimov 《Applied Biochemistry and Microbiology》2011,47(5):549-555
Influence of mediators of the signal systems of salicylic (SA) and jasmonic (JA) acids and their mixture on reactive oxygen
species’ (ROS) (superoxide radical and O2·− H2O2) generation and activity of oxidoreductases (oxalate oxidase, peroxidase and catalase) in leaves of wheat Triticum aestivum L. infected by Septoria leaf blotch pathogen Septoria nodorum Berk has been studied. Presowing treatment of seeds by SA and JA decreased the development rate of fungus on wheat leaves.
SA provided earlier inductive effect on production of O2·− and H2O2 compared with JA. The protective effect of the salicylic and jasmonic acids against Septoria leaf blotch pathogen was caused
by activation of oxalate oxidase, induction of anion and cation peroxidases, and decrease of catalase activity. Ability of
compounds to stimulate ROS in the plant tissues can be used as criteria for evaluation of immune-modulating activity of new
substances for protection of the plants. 相似文献
108.
Maksimov VF Korostyshevskaia IM 《Rossi?skii fiziologicheski? zhurnal imeni I.M. Sechenova / Rossi?skaia akademiia nauk》2011,97(3):263-275
Classic and modern data on natriuretic peptide hormones that are synthesized in cardiac atria and participate in hemodynamic and water-salt balance regulation are summarized in this paper. Cumulated data on polypeptide variety, their structure, intracellular syntheses, physiological effects and concentration alterations during model experiments and cardiovascular pathology are presented. Unsolved problems including methods of plasma peptides concentration measurements, their role in heart failure development, and their clinical significance are discussed. 相似文献
109.
Korostyshevskaia IM Maksimov VF Markel' AL Shmerling MD Buzueva II Filiyshina EE Iakobson GS 《Rossi?skii fiziologicheski? zhurnal imeni I.M. Sechenova / Rossi?skaia akademiia nauk》2007,93(2):169-179
Treatment with different types of antihypertensive drugs during second month age has not prevented development of arterial hypertension and myocardial hypertrophy in the adult rats with inherited stress-induced arterial hypertension. At 6 months of age, the 11% attenuation of basal blood pressure has beet achieved only in the rats treated with angiotensin-converting enzyme inhibitor enalapril. Nevertheless, they expressed the most pronounced left ventricular hypertrophy. The unfavorable tissue and ultrastructural abnormalities were revealed in the myocardium of the rats which received the alpha1-adrenoceptor blocker terazosin. The delayed effects of losartan (angionetsin II receptor antagonist) and corinfar (calcium channel antagonist) on the myocardial structure were inessential. 相似文献
110.
A. Yu. Maksimov Yu. G. Maksimova M. V. Kuznetsova V. F. Olontsev V. A. Demakov 《Applied Biochemistry and Microbiology》2007,43(2):173-177
Rhodococcus ruber strain gt1, possessing nitrile hydratase activity, was immobilized by adsorption on carbon supports differing in structure and porosity. The adsorption capacity of the supports towards cells, the substrate of the nitrile hydratase reaction (acrylonitrile), and the product (acrylamide) was studied. Also, the effect of immobilization on nitrile hydratase activity of bacteria was investigated, and the operational stability of the immobilized biocatalyst was determined. It was shown that crushed and granulated active coals were more appropriate for immobilization than fibrous carbon adsorbents. 相似文献