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31.
T. S. Zaporozhets N. N. Besednova T. A. Kuznetsova T. N. Zvyagintseva I. D. Makarenkova S. P. Kryzhanovsky V. G. Melnikov 《Russian Journal of Marine Biology》2014,40(1):1-9
Based on our own and current literature data, we analyzed the prebiotic properties of polysaccharides and extracts of seaweeds. The role of prebiotics, particularly polysaccharides, in the normalization of intestinal microflora is discussed; consideration is also given to the possibility of seaweed polysaccharide fermentation by colonic microflora and selective stimulation of the growth of colonic bifidobacteria. This review also analyzes other useful properties of seaweed polysaccharides and discusses the prospects for inclusion of seaweed polysaccharides in the composition of functional nutrition products for the purposes of correcting intestinal bacterial disorders and inflammatory processes and normalizing the immune and metabolic status. 相似文献
32.
ABE production from corn: a recent economic evaluation 总被引:2,自引:0,他引:2
This article details an economic assessment of butanol production from corn using the newly developed hyper-butanol-producing
strain of Clostridium beijerinckii BA101. Butanol is produced in batch reactors and recovered by distillation. For a plant with 153,000 metric tons of acetone,
butanol, and ethanol (ABE) production capacity, the production equipment cost and total working capital cost is US$33.47×106 and US$110.46×106, respectively. Based on a corn price (C
p) of US$79.23 ton−1 (US$2.01 bushel−1), an ABE yield of 0.42 (g ABE/g glucose) butanol price is projected to be US$0.34 kg−1. An improved yield of 0.50 will reduce this price to US$0.29 kg−1. Assumptions, such as by-product credit for gases and complete conversion of corn steep liquor (CSL) to fermentation by-products,
have been taken into consideration. An increased price of corn to US$197.10 ton−1 would result in a butanol price of US$0.47 kg−1. A grass-rooted plant would result in a butanol price of US$0.73 kg−1 (C
p US$79.23 ton−1). In a worst case scenario, the price of butanol would increase to US$1.07 kg−1 (C
p 197.10 ton−1 for a grass-rooted plant and assuming no credit for gases). This is based on the assumption that corn price would not increase
to more than US$197.10 ton−1.
Journal of Industrial Microbiology & Biotechnology (2001) 27, 292–297.
Received 12 September 2000/ Accepted in revised form 12 January 2001 相似文献
33.
Features of incorporation of cefazolin, ampicillin, kanamycin and gentamicin into erythrocytic shadows in patients with abdominal diseases and apparently healthy persons during hypoosmotic hemolysis were studied. The highest percentage of kanamycin and gentamicin incorporation into the erythrocytic shadows was observed. The parameter of the antibiotic incorporation from the incubation fluid into the erythrocytic shadows depended on the antibiotic type and dose. Rather significant resistance of the erythrocytic carriers with incorporated gentamicin to possible desorption and excretion of the antibiotic from the shadows into the blood flow was revealed which made their use possible for target release of antibiotics in the liver. 相似文献
34.
Brigitte Boxma Guenola Ricard Angela HAM van Hoek Edouard Severing Seung-Yeo Moon-van der Staay Georg WM van der Staay Theo A van Alen Rob M de Graaf Geert Cremers Michiel Kwantes Neil R McEwan C Jamie Newbold Jean-Pierre Jouany Tadeusz Michalowski Peter Pristas Martijn A Huynen Johannes HP Hackstein 《BMC evolutionary biology》2007,7(1):1-12
Background
The hydrogenosomes of the anaerobic ciliate Nyctotherus ovalis show how mitochondria can evolve into hydrogenosomes because they possess a mitochondrial genome and parts of an electron-transport chain on the one hand, and a hydrogenase on the other hand. The hydrogenase permits direct reoxidation of NADH because it consists of a [FeFe] hydrogenase module that is fused to two modules, which are homologous to the 24 kDa and the 51 kDa subunits of a mitochondrial complex I.Results
The [FeFe] hydrogenase belongs to a clade of hydrogenases that are different from well-known eukaryotic hydrogenases. The 24 kDa and the 51 kDa modules are most closely related to homologous modules that function in bacterial [NiFe] hydrogenases. Paralogous, mitochondrial 24 kDa and 51 kDa modules function in the mitochondrial complex I in N. ovalis. The different hydrogenase modules have been fused to form a polyprotein that is targeted into the hydrogenosome.Conclusion
The hydrogenase and their associated modules have most likely been acquired by independent lateral gene transfer from different sources. This scenario for a concerted lateral gene transfer is in agreement with the evolution of the hydrogenosome from a genuine ciliate mitochondrion by evolutionary tinkering. 相似文献35.
36.
T. A. Kuznetsova N. N. Besednova N. N. Kovalev L. M. Somova V. V. Usov I. D. Makarenkova N. G. Plekhova E. I. Drobot 《Russian Journal of Marine Biology》2016,42(5):427-432
This article presents the experimental data on the testing of new wound dressings, viz., porous plates, prepared on the basis of chitosan and calcium alginate that contain biologically active substances (BASs) derived from marine hydrobionts. In a burn wound model in guinea pigs, we revealed a positive effect of tested samples of wound dressings on the wound-healing process; the data of planimetric and pathomorphological studies showing the acceleration of the process of regeneration in the wound are discussed. It was noted that the dynamics and patomorphological characteristics of the wound healing process differed depending on the structure of the BAS included into the composition of wound dressings (peptides, sulfated polysaccharides, a complex of amino acids and peptides). 相似文献
37.
Jessica G Borger Sheila L Brown Lisa M Connor Adam NR Cartwright Annette M Dougall Ruud HP Wilbers Peter C Cook Lucy H Jackson‐Jones Alexander T Phythian‐Adams Cecilia Johansson Daniel M Davis Benjamin G Dewals Franca Ronchese Andrew S MacDonald 《The EMBO journal》2017,36(16):2404-2418
Type 2 inflammation is a defining feature of infection with parasitic worms (helminths), as well as being responsible for widespread suffering in allergies. However, the precise mechanisms involved in T helper (Th) 2 polarization by dendritic cells (DCs) are currently unclear. We have identified a previously unrecognized role for type I IFN (IFN‐I) in enabling this process. An IFN‐I signature was evident in DCs responding to the helminth Schistosoma mansoni or the allergen house dust mite (HDM). Further, IFN‐I signaling was required for optimal DC phenotypic activation in response to helminth antigen (Ag), and efficient migration to, and localization with, T cells in the draining lymph node (dLN). Importantly, DCs generated from Ifnar1?/? mice were incapable of initiating Th2 responses in vivo. These data demonstrate for the first time that the influence of IFN‐I is not limited to antiviral or bacterial settings but also has a central role to play in DC initiation of Th2 responses. 相似文献
38.
Larissa A. Balabanova Irina Yu. Bakunina Olga I. Nedashkovskaya Ilona D. Makarenkova Tatiana S. Zaporozhets Natalia N. Besednova Tatiana N. Zvyagintseva Valery A. Rasskazov 《Marine biotechnology (New York, N.Y.)》2010,12(1):111-120
An α-galactosidase capable of converting B red blood cells into the universal blood type cells at the neutral pH was produced
by a novel obligate marine bacterium strain KMM 701 (VKM B-2135 D). The organism is heterotrophic, aerobic, and halophilic
and requires Na+ ions and temperature up to 34°C for its growth. The strain has a unique combination of polysaccharide-degrading enzymes.
Its single intracellular α-galactosidase exceeded other glycoside hydrolases in the level of expression up to 20-fold. The
α-galactosidase was purified to determine the N-terminal amino acid sequences and new activities. It was found to inhibit
Corynebacterium diphtheria adhesion to host buccal epithelium cell surfaces with high effectiveness. The nucleotide sequence of the homodimeric α-galactosidase
indicates that its subunit is composed of 710 amino acid residues with a calculated Mr of 80,055. This α-galactosidase shares structural property with 36 family glycoside hydrolases. The properties of the enzyme
are likely to be highly beneficial for medicinal purposes. 相似文献
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40.
Makarenkova ID Zaporozhets TS Besednova NN Khoroshevskaia IuN Cherdantseva GK 《Zhurnal mikrobiologii, epidemiologii, i immunobiologii》2000,(6):6-9
The study of the main pathogenicity factors of C. diphtheriae (adhesive activity, toxigenicity, detection of tox+ gene) circulating in the Primorski Territory has been made. As revealed in this study, at the period of declined epidemic process due to mass immunization of the adult and child population against diphtheria the selection of C. diphtheriae strains with weak toxigenicity and low adhesiveness was observed. No strains having tox+ genes have been detected among C. diphtheriae nontoxigenic strains circulating in the Primorski Territory. 相似文献