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321.
Olubu A Adiji Maite L Docampo-Palacios Anislay Alvarez-Hernandez Giulio M Pasinetti Xiaoqiang Wang Richard A Dixon 《Plant physiology》2021,185(4):1617
Mammalian phase II metabolism of dietary plant flavonoid compounds generally involves substitution with glucuronic acid. In contrast, flavonoids mainly exist as glucose conjugates in plants, and few plant UDP-glucuronosyltransferase enzymes have been identified to date. In the model legume Medicago truncatula, the major flavonoid compounds in the aerial parts of the plant are glucuronides of the flavones apigenin and luteolin. Here we show that the M. truncatula glycosyltransferase UGT84F9 is a bi-functional glucosyl/glucuronosyl transferase in vitro, with activity against a wide range of flavonoid acceptor molecules including flavones. However, analysis of metabolite profiles in leaves and roots of M. truncatula ugt84f9 loss of function mutants revealed that the enzyme is essential for formation of flavonoid glucuronides, but not most flavonoid glucosides, in planta. We discuss the use of plant UGATs for the semi-synthesis of flavonoid phase II metabolites for clinical studies.UGT84F9 is a bifunctional glucuronosyltransferase/glucosyltransferase that is necessary for the glucuronidation of a wide range of flavonoid natural products in Medicago truncatula. 相似文献
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323.
Lucena-Frédou Flávia Mourato Bruno Frédou Thierry Lino Pedro G. Muñoz-Lechuga Rubén Palma Carlos Soares Andrey Pons Maite 《Reviews in Fish Biology and Fisheries》2021,31(3):709-736
Reviews in Fish Biology and Fisheries - Despite being an important source of wealth and food security for many countries, most of the small tuna stocks in the Atlantic Ocean and Mediterranean Sea... 相似文献
324.
Andrea Comba Luciana L. Almada Ezequiel J. Tolosa Eriko Iguchi David L. Marks Marianela Vara Messler Renata Silva Maite G. Fernandez-Barrena Elisa Enriquez-Hesles Anne L. Vrabel Bruno Botta Lucia Di Marcotulio Volker Ellenrieder Aldo R. Eynard Maria E. Pasqualini Martin E. Fernandez-Zapico 《The Journal of biological chemistry》2016,291(4):1933-1947
325.
The prevalence of coccidian parasites in three Octopus tehuelchus populations from San Matías Gulf (Patagonia, Argentina) is compared. The prevalence was similar between sexes, but varied between seasons (being highest during cold months) and sites. Islote Lobos had the highest prevalence (42.7–100%) followed by San Antonio Bay (0–66%) and El Fuerte (0–24.5%). Octopuses under 27 mm of dorsal mantle length showed a low prevalence (less than 50%), which increased with size. We hypothesize that the high prevalence of parasites, which affect the three populations differentially, could account for the observed variability in life-span and growth, size–frequency distributions, reproduction and densities of O. tehuelchus populations. 相似文献
326.
Bacteriophages are one of the most abundant entities on the planet and are present in high concentrations within humans and animals, mostly in the gut. Phages that infect intestinal bacteria are released by defecation and remain free in extra‐intestinal environments, where they usually persist for longer than their bacterial hosts. Recent studies indicate that a large amount of the genetic information in bacterial genomes and in natural environments is of phage origin. In addition, metagenomic analysis reveals that a substantial number of bacterial genes are present in viral DNA in different environments. These facts support the belief that phages can play a significant role in horizontal gene transfer between bacteria. Bacteriophages are known to transfer genes by generalized and specialized transduction and indeed there are some examples of phages found in the environment carrying and transducing genes of bacterial origin. A successful transduction in the environment requires certain conditions, e.g. phage and bacterial numbers need to exceed certain threshold concentrations, the bacteria need to exist in an infection‐competent physiological state, and lastly, the physical conditions in the environment (pH, temperature, etc. of the supporting matrix) have to be suitable for phage infection. All three factors are reviewed here, and the available information suggests: (i) that the number of intestinal bacteria and phages in faecally contaminated environments guarantees bacteria–phage encounters, (ii) that transduction to intestinal bacteria in the environment is probable, and (iii) that transduction is more frequent than previously thought. Therefore, we suggest that phage‐mediated horizontal transfer between intestinal bacteria, or between intestinal and autochthonous bacteria in extra‐intestinal environments, might take place and that its relevance for the emergence of new bacterial strains and potential pathogens should not be ignored. 相似文献
327.
Blath Jochen Buzzoni Eugenio González Casanova Adrián Wilke-Berenguer Maite 《Journal of mathematical biology》2019,79(1):369-392
Journal of Mathematical Biology - We investigate various aspects of the (biallelic) Wright–Fisher diffusion with seed bank in conjunction with and contrast to the two-island model analysed... 相似文献
328.
Maite Mascaro Luis E. Hidalgo Xavier Chiappa-Carrara Nuno Simoes 《Marine and Freshwater Behaviour and Physiology》2013,45(3):143-159
Size-selective predation by small (30-50 mm carapace width) and large (90-110 mm) Callinectes sapidus when feeding on three different size classes of Litopenaeus setiferus was investigated. Laboratory experiments using no-choice and multiple-choice designs were carried out. Active and passive components of predation were evaluated by comparing the probability of attacking (active) and capturing (passive) shrimp. Small C. sapidus consumed shrimp of all size classes in similar frequencies during multiple and no-choice experiments, and the probability of attacking and capturing shrimp of all size classes was similar. Large crabs consumed large shrimp with a significantly higher frequency during multiple than during no-choice experiments, and the probability of capturing large shrimp was significantly higher than medium and small ones. Results in the present study suggest that size-specific consumption rates of C. sapidus are mainly the result of a passive mechanism associated with the salience of shrimp to predation. However, an active component of foraging behaviour related to the decision to attack an alternative prey whilst consuming one that has already been captured, helps to explain the differences in shrimp consumption between multiple and no-choice experiments. The complex interaction between active, passive components and satiation is discussed. 相似文献
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330.
Summary Phenol-degrading strain QT 31 ofPseudomonas sp. was selected among other phenol-resistant bacteria from activated sludges of wastewater treatment plant of an oil refinery. Its capacity of degradation was studied at different periods of adaptation, reaching a phenol biodegradation rate of 28 mg/l phenol per hour, from minimal, medium with 1000 mg/l phenol, after adaptation for 20 days. 相似文献