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21.
The first record of subtropical insects (Thysanoptera) in central Europe: long‐distance transport of airborne thrips,applying three‐dimensional backward trajectories 下载免费PDF全文
László Makra Károly Bodnár Andrea Fülöp Szilvia Orosz Ágnes Szénási Zoltán Csépe Gábor Jenser Gábor Tusnády Donát Magyar 《Agricultural and Forest Entomology》2018,20(3):301-326
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22.
Magyar D 《Acta microbiologica et immunologica Hungarica》2002,49(2-3):227-234
Atmospheric ascospores have been monitored using volumetric spore trap. Spore concentration data were analysed using Spearman's correlation. Our results show that the meteorological factor with the greatest effect on spore concentration was the duration of rain. Temperature increase strongly reduced the ascospore concentration; but the length of windless periods resulted in an increase in spore count. The only measurable effect wind perse actually had on spore count, was registered when a strong wind blew after a long windless period. We observed that the count of ascospores during wet weather could surpass the total concentration of dry conidia measured on a typical, highly polluted summer day. Using selected air samples to study the effect of storms, certain aspects of long-distance spore transport were elucidated. We describe here three main strategies for long-range ascospore transport, "splash-off", "secondary emission" and "sporematrix projectiles". 相似文献
23.
Novel cell-penetrating alpha-keto-amide calpain inhibitors as potential treatment for muscular dystrophy 总被引:1,自引:0,他引:1
Lescop C Herzner H Siendt H Bolliger R Henneböhle M Weyermann P Briguet A Courdier-Fruh I Erb M Foster M Meier T Magyar JP von Sprecher A 《Bioorganic & medicinal chemistry letters》2005,15(23):5176-5181
Dipeptide-derived alpha-keto-amide compounds with potent calpain inhibitory activity have been identified. These reversible covalent inhibitors have IC(50) values down to 25nM and exhibit greatly improved activity in muscle cells compared to the reference compound MDL28170. Several novel calpain inhibitors have shown positive effects on histological parameters in an animal model of Duchenne muscular dystrophy demonstrating their potential as a treatment option for this fatal disease. 相似文献
24.
M. Hollsi Zs. Majer A. Z. Rnai A. Magyar K. Medzihradszky S. Holly A. Perczel G. D. Fasman 《Biopolymers》1994,34(2):177-185
Comparative CD and Fourier transform ir (FTIR) spectroscopic data on N-Boc protected linear peptides with or without the (Pro-Gly) β-turn motif (e.g., Boc-Tyr-Pro-Gly-Phe-Leu-OH and Boc-Tyr-Gly-Pro-Phe-Leu-OH) are reported herein. The CD spectra, reflecting both backbone and aromatic contributions, were not found to be characteristic of the presence of β-turns. In the amide I region of the FTIR spectra, analyzed by self-deconvolution and curve-fitting methods, the β-turn band shewed up between 1639 and 1633 cm?1 in trifluoroethanol (TFE) but only for models containing the (Pro-Gly) core. This band war-also present in the spectra in chloroform but absent in dimethylsulfoxide. These findings, in agreement with recent ir data on cyclic models and 310-helical polypeptides and protein in D2O [see S. J. Prestrelski, D. M. Byler, and M. P. Thompson (1991), International Journal of Peptide and Protein Research, Vol. 37, pp. 508–512; H. H. Mantsch, A. Perczel. M. Hollósi, and G. D. Fasman (1992), FASEB Journal, Vol. 6, p. A341; H. H. Mantsch. A. Perczel, M. Hollósi, and G. Fasman (1992), Biopolymers. Vol. 33, pp. 201–207; S. M. Miick, G. V. Martinez, W. R. Fiori, A. P. Tedd, and G. L. Millhauser (1992). Nature, Vol. 359, pp. 653–655], suggest that the amide I band, with a major contribution from the acceptor C ? O of the 1 ← 4 intramolecular H bond of β-turns, appears near or below 1640 cm?1, rather than above 1660 cm?1. In TFE, bands between 1670 and 1660 cm?1 are mainly due to “free” carbonyls, that is, C ? O's of amides that are solvated but not involved in the characteristic H bonds of periodic secondary structures or β-turns. © 1994 John Wiley & Sons, Inc. 相似文献
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Miklós Csala Beáta Lizák Éva Margittai Judit É. Magyar Gábor Bánhegyi 《生物化学与生物物理学报:生物膜》2007,1768(6):1325-1341
Enzyme activities localized in the luminal compartment of the endoplasmic reticulum are integrated into the cellular metabolism by transmembrane fluxes of their substrates, products and/or cofactors. Most compounds involved are bulky, polar or even charged; hence, they cannot be expected to diffuse through lipid bilayers. Accordingly, transport processes investigated so far have been found protein-mediated. The selective and often rate-limiting transport processes greatly influence the activity, kinetic features and substrate specificity of the corresponding luminal enzymes. Therefore, the phenomenological characterization of endoplasmic reticulum transport contributes largely to the understanding of the metabolic functions of this organelle. Attempts to identify the transporter proteins have only been successful in a few cases, but recent development in molecular biology promises a better progress in this field. 相似文献
27.
Eszter Borbála Both Shuxun Shao Jiqian Xiang Zsuzsa Jókai Hongqing Yin Yafeng Liu Anna Magyar Mihály Dernovics 《Biochimica et Biophysica Acta (BBA)/General Subjects》2018,1862(11):2354-2362
Background
Selenium hyperaccumulation in plants often involves the synthesis of non-proteinaceous methylated selenoamino acids serving for the elimination of excess selenium from plant metabolism to protect plant homeostasis.Methods
Our study aimed at the identification of the main selenium species of the selenium hyperaccumulator plant Cardamine violifolia (Brassicaceae) that grows in the wild in the seleniferous region of Enshi, China. A sample of this plant (3.7?g?Se?kg?1 d.w.) was prepared with several extraction methods and the extracted selenium species were identified and quantified with liquid chromatography mass spectrometry set-ups.Results
The Cardamine violifolia sample did not contain in considerable amount any of the organic selenium species that are often formed in hyperaccumulator plants; the inorganic selenium content (mostly as elemental selenium) accounted only for <20% of total Se. The most abundant selenium compound, accounting for about 40% of total Se was proved to be selenolanthionine, a selenium species that has never been unambiguously identified before from any selenium containing sample. The identification process was completed with chemical synthesis too. The molar ratio of lanthionine:selenolanthionine in the water extract was ca. 1:8.Conclusions
Finding selenolanthionine as the main organic selenium species in a plant possibly unearths a new way of selenium tolerance. This article is part of a Special Issue entitled Selenium research in biochemistry and biophysics - 200?year anniversary issue, edited by Dr. Elias Arnér and Dr. Regina Brigelius-Flohe. 相似文献28.
Pal Soltesz Daniel Bereczki Peter Szodoray Maria T Magyar Henrietta Der Istvan Csipo Agota Hajas Gyorgy Paragh Gyula Szegedi Edit Bodolay 《Arthritis research & therapy》2010,12(3):R78
Introduction
The aim of the present study was to investigate the association between cardiovascular risk factors and endothelial dysfunction in patients with mixed connective tissue disease (MCTD) and to determine which biomarkers are associated with atherosclerotic complications, such as cardiovascular disease. 相似文献29.
Gene silencing experiments in difficult-to-transfect cells are often hampered by the presence of a background of untransfected cells. We present proof-of-concept data from two different strategies for enrichment of siRNA-transfected cells. In the first approach, a heterologous surface antigen is expressed from a plasmid that is co-transfected with an siRNA targeting an endogenous mRNA. The surface antigen is then used for enrichment of successfully transfected cells using antibody-coated magnetic particles. In the second strategy, a eukaryotic antibiotic resistance gene is expressed from a co-transfected plasmid. Addition of the corresponding antibiotic 24h after transfection results in killing of untransfected cells, which can be washed away. Elimination of untransfected cells will allow more accurate interpretation of the effects of gene silencing. 相似文献
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