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On Pluralism and Competition in Evolutionary Explanations 总被引:1,自引:0,他引:1
A controversy arose concerning the adaptive significance ofclitoral orgasm, disputing whether the presence of the traitin females is explained by appeal to developmental processesor natural selection (Gould, 1987a, b; Alcock, 1987). In response,Sherman (1988) offered a pluralistic solution in terms of levelsof analysis in which Gould and Alcock's disagreement was construedas semantic and not substantial. I argue that Sherman's solutionis mistaken. I suggest that the nature of the Gould/Alcock disputeis better understood by considering the abstract structure ofscientific theories and their role in explanation. This accountleads to a representation of science as having a plurality oftheoretical models which are integrated piecemeal in the explanationof concrete phenomena. 相似文献
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Application of polar-orbiting, meteorological satellite data to detect flooding of Rift Valley Fever virus vector mosquito habitats in Kenya 总被引:1,自引:0,他引:1
K. J. LINTHICUM C. L. BAILEY C. J. TUCKER K. D. MITCHELL T. M. LOGAN† F. G. DAVIES‡ C. W. KAMAU† P. C. THANDE† J. N. WAGATEH† 《Medical and veterinary entomology》1990,4(4):433-438
Measurements of green-leaf vegetation dynamics recorded by the advanced very high resolution radiometer instruments onboard National Oceanic and Atmospheric Administration satellites 7 and 9 were used to derive ground moisture and rainfall patterns in Kenya and monitor resultant flooding of mosquito larval habitats (dambos) likely to support Rift Valley Fever virus vector mosquitoes (Aedes and Culex spp.). Satellite-derived data from mid-1981 to December 1988 have been analysed with corresponding rainfall, flooding and vector population data as they relate to Rift Valley Fever virus ecology. Single (7 x 7 km) and multiple grid-cell image analysis (200 x 300 km) in small localized areas and large geographical regions, respectively, of vegetation data were used to quantify the potential for flooding of mosquito breeding habitats. The ability to detect accurately parameters, such as ground moisture, that determine flooding could provide local officials with sufficient warning to allow for implementation of specific mosquito control measures before a disease outbreak. 相似文献
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Ovaries of neonatal rats are not endowed with specific LH/hCG receptors up to 6–8 days of age. Treatment of ovarian membranes of the neonatal rat with neuraminidase results in a specific binding of radioactively labeled hCG, while an increase of hormone binding is observed after neuraminidase treatment of ovarian membranes of the 21-day-old rat. These changes in hormone receptor sites in the ovary are dependent on the neuraminidase concentration used and are due to a receptor with a dissociation constant (KD ) of about 10−9 M. The KD of the receptor in the LH/hCG sensitive ovary without neuraminidase treatment is about 10−10 M. These results indicate the presence of two different LH/hCG receptors in the ovarian membrane. The unmasking effect of neuraminidase onto LH/hCG receptors indicate that ganglioside-like structures are responsible for the masking of receptors in the neonatal, insensitive rat ovary and also in the 21-day-old sensitive ovary. Ganglioside preparations are able to inhibit the binding, and the fractionation of ovary gangliosides results in a fraction with a rather high inhibition potency of LH/hCG binding to the receptor. It is hypothesized that the masked receptors in the sensitive period represent a store of receptors for the reconstitution of the ovarian cells with active receptors after internalization of the hormone-receptor complex. Thus the masking of the receptors in the early postnatal rat ovary could be a prerequisite for the female differentiation of hypothalamic centers. The observed neuraminidase effect in vitro could reflect a physiologic situation. Neuraminidase was found in the ovary, and during early postnatal development the neuraminidase activity pattern coincides with that of the ovarian LH/hCG receptor changes. 相似文献
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ABSTRACT. Electron microscopy of schizont development in erythrocytic Plasmodium knowlesi has revealed that spheroidal vacuoles 250 nm in diameter with semi-dense contents appear at the periphery of the parasite prior to the budding of merozoites. When treated with non-polar solvents, their contents are completely extracted, and after fixation in tannic-glutaraldehyde they contain regular lamellae with a periodicity of 5.5 nm. Both of these reactions are typical of lipids. Some of these structures are associated with phagosomal vacuoles which may contribute to their lamellae. They disappear at the onset of merozoite formation, but membranous whorls of various sizes continue to be associated with the schizont surface during budding of merozoites. It is suggested that the lipidic vacuoles are a source of preformed lipid which can be utilized rapidly during the generation of merozoites. 相似文献
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