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991.
992.
TRB3 interacts with CtIP and is overexpressed in certain cancers 总被引:2,自引:0,他引:2
Xu J Lv S Qin Y Shu F Xu Y Chen J Xu BE Sun X Wu J 《Biochimica et biophysica acta》2007,1770(2):273-278
TRB3, a human homolog of Drosophila Tribbles, has been recently shown as a critical negative regulator of Akt and S6 kinase activation in a number of cellular processes. Here we found that TRB3 interacted with an important cell cycle regulator CtIP (CtBP-interacting protein) and the interaction involved the C-terminus of both proteins. Interestingly, TRB3 and CtIP co-localized to the nucleus in HeLa cells and exhibited a unique dot-like pattern. Finally, we demonstrated that TRB3 was overexpressed in multiple tumor tissues. Since CtIP plays important roles in cell cycle checkpoint control and it has been implicated in tumorigenesis, our data suggest that TRB3 may be involved in these biological processes through interacting with CtIP. 相似文献
993.
In a sand culture experiment we investigated the effects of boron (0.01, 0.19, 0.46 and 0.93 mol m−3 B, as H3BO3), sodium chloride (0, 100 and 200 mol m−3 NaCl) and combined B and NaCl, over 36 days, on growth, water use and foliar ion concentrations of nine week-old seedlings
of three fast-growing, commercial eucalypts ( Eucalyptus camaldulensis Dehnh. , E. globulus Labill. ssp. globulus and E. grandis
W.Hill.). Shoot dry weight was significantly reduced by high concentrations of NaCl (p < 0.001) and by B and NaCl in combination
(p ≤ 0.05) but not by B alone. Root dry weight was significantly reduced by both NaCl (p < 0.001) and B (p < 0.001), but not
by combined B and NaCl. Foliar B concentrations increased with higher concentrations of applied B and decreased with higher
NaCl concentrations. Foliar Na concentrations were greater with higher NaCl concentrations, whereas B application had no significant
effect on foliar Na concentrations. All three species accumulated relatively high B concentrations in leaves. Severe boron
toxicity symptoms (BTS) were apparent only when leaf B concentrations exceeded 50 mol x 10−6 g−1, but even at these high concentrations plant growth was only slightly reduced. E. camaldulensis showed least development
of BTS, the lowest leaf B concentrations and least reduction in height growth due to B and NaCl. The results suggest that
there was a correlation between both B tolerance and B accumulation in leaves and between tolerance to B and NaCl.
This revised version was published online in June 2006 with corrections to the Cover Date. 相似文献
994.
大兴安岭地区紫貂的活动节律 总被引:10,自引:1,他引:9
借助无线电遥测技术,对4只紫貂全年的活动节律进行了研究,结果表明,紫貂的活动节律春季和冬季的高峰是在晨昏二个阶段,夏秋二季的活动高峰在白昼。春季总体活动节律与夏季相比有明显差异(F=4.499,df=1,22,23;P=0.045),春季与秋季的活动节律也有差异(F=7.039;df=1,22,23;P=0.015)。其总体平均活动强度,春季活动量最小(17.53%),夏季最高(38.29%),其 相似文献
995.
钙调素的结构生物学研究进展 总被引:1,自引:0,他引:1
介绍了Apo-CaM、Ca2+-CaM以及CaM与其靶肽及拮抗剂复合体的空间结构.钙调素(calmodulin, CaM)作为细胞多功能的Ca2+受体,在细胞信号转导过程中发挥重要作用.近几年对它的空间结构有了较清楚的了解,使人们能够更明确地认识CaM的Ca2+激活及CaM与其靶酶的作用机制. 相似文献
996.
蒙古栎红松林演替模型FOROAK的研究 总被引:2,自引:0,他引:2
Based on forest dynamics theory, gap model FOROAK was developed for simulating long-termdynamics of Mongolian oak (Quercus rnongolica Fisch. )-Korean pine (Pinus koraiensis Sieb. et Zucc. )forest. The model included two parts: biological growth and environmental impacts on growth. Different areapatches were used in simulating forest changes. The results showed that this forest gap was 0.05 hm2. Themodel testing demonstrated that it could reasonably simulate forest dynamic process, and had a very highaccuracy to predict species compositions. The observed species basal areas was similar to the predicted at 60,100 and 270 year forests, the observed species compositions were similar to the predicted at old forest period.Complex changes were found through modeling forest dynamics of bare ground. Mongolian oak and white birch( Betula platyphylla Sukacz. ) dominated at early stage, forest dominated by broad leaved species was formedat middle stage, and then Korean pine dominated at latter stage. The prediction of current primary forestshowed that it was steady during the next 300 year period, the number of trees and the biomass of Korean pine changed very little. 相似文献
997.
It was reported that the growth of Dunaliella salina Teod. cultured in medium containing 1 mol/L NaC1 was almost completely inhibited by the addition of 100 mmol/L KC1. The high K+ (100 mmol/L KC1) treatment also significantly inhibited the photosynthetic rate of D. salina and decreased chlorophyll contents in algae. This study focuses on possible effects of high K+ or alkaline pH on the ultrastructural change of chloroplasts in D. salina. After D. salina was cultured in a medium containing 100 n,anol/L KC1 or in a medium with alkaline pH for 8 to 10 days, dramatic ultrastructural changes occurred in the chloroplasts including thylakoid swelling, volume increase of chloroplast, and significant accumulation of starch grains in chloroplasts. The results are consistent with our previous report indicating that the ultrastmctuml changes in chloroplast under high K + or alkaline pH may lead to an inhibitory effects on photosynthesis and overall growth of D. salina. 相似文献
998.
Genomic constitution of octoploid wheat-wheatgrass amphiploid Zhong 2 was analyzed by chromosome pairing and fluorescence in sim hybridization techniques. The results indicated that the octoploid wheatwheatgrass chromosomes in Zhong 2 were derived from the distant homologous genomes of wheatgrass ( Agropyron intermedium (Host) P.B. = Elytrigia intermedia (Host) Nevski = Thinotopyrum intermedium (Host) Barkworth and Dewey, and thew distant homologous genomes were not from the E geaome of T. elongatum 2x. Zhong 2 contained 12 wheatgrass chromosomes in which a pair of chromosomes was involved in translocation between wheatgrass and wheat chromosomes. 相似文献
999.
EF—Tumt和EF—Tsmt在不同发育阶段小鼠各组织中的表达分析 总被引:1,自引:0,他引:1
线粒体蛋白质翻译延长因子Tu和Ts(mitochondrialelongationfactorTuandTs,EFTumtandEFTsmt)是由核基因编码的两个蛋白质,它们的功能和调控对细胞的生长发育有重要意义。采用EFTumt和EFTsmt重组蛋白分别制备了抗EFTumt和抗EFTsmt特异抗体并以此检测了它们在小鼠不同发育时期心肌、骨骼肌、肝、脑、脾等组织中的表达。蛋白质印迹结果表明EFTumt和EFTsmt在各组织中的表达水平不同、有明显的组织差异性,并都受发育的调节。EFTumt在同一发育时期各组织中的表达及随发育的变化趋势与EFTsmt基本一致。结果提示EFTumt和EFTsmt的表达水平与组织细胞能量代谢水平密切相关,它们不仅在体内以复合体形式发挥作用,其基因表达可能受同一机制的调控。 相似文献
1000.
Z6/陕7859胚培养再生植株的细胞遗传学研究与易位系选育 总被引:6,自引:0,他引:6
二体附加系Z6携带抗大麦黄矮病毒病基因,为了将其抗性导入小麦,将Z6与普通小麦陕7859杂交,杂种F1经幼胚培养诱导形成再生植株,对再生植株及后代进行抗性鉴定,农艺性状考察及对SC2部分抗病植株花粉母细胞减数分裂期染色体行为进行了观察。结果表明,(1)SC2不同单株间存在染色体数目,结构的变异。(2)同一再生植株后代的不同单株,染色体数目可能相同,但染色体组成及减数分裂期行为可心不同,致使后代抗性 相似文献