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991.
Luis M. Chiappe 《Evolution》2009,2(2):248-256
Living birds are the most diverse land vertebrates and the heirs of a rich chapter in the evolution of life. The origin of
modern birds from animals similar to Tyrannosaurus rex is among the most remarkable examples of an evolutionary transition. A wealth of recently discovered fossils has finally
settled the century-old controversy about the origin of birds and it has made the evolutionary saga toward modern birds one
of the best documented transitions in the history of life. This paper reviews the evidence in support of the origin of birds
from meat-eating dinosaurs, and it highlights the array of fossils that connect these fearsome animals with those that fly
all around us. 相似文献
992.
Brandon Schlautman Luis Diaz-Garcia Giovanny Covarrubias-Pazaran Nathan Schlautman Nicholi Vorsa James Polashock Elizabeth L. Ogden Allan Brown Ying-Chen Lin Nahla Bassil Emily J. Buck Claudia Wiedow Susan McCallum Julie Graham Massimo Iorizzo Lisa J. Rowland Juan Zalapa 《Molecular breeding : new strategies in plant improvement》2018,38(1):9
Cranberry and blueberry are closely related and recently domesticated fruit crops in the genus Vaccinium. Both have a presumed American origin and likely evolved from a common ancestor; however, details of their adaptive radiation and the extent of their genomic divergence remains little understood. To better understand their evolutionary and genomic relationships, a set of 323 cross-transferable simple sequence repeat (SSR) markers were identified, added to existing marker datasets, and used to construct linkage maps for cranberry (582 SSRs) and an interspecific diploid blueberry population (V. darrowii x V. corymbosum) x V. corymbosum (409 markers, densest blueberry SSR map currently available). The maps allowed for the first comparative genetic mapping study in Vaccinium, and revealed a surprisingly high degree of macro-synteny and collinearity between the cranberry and blueberry genomes. Approximately 93% of the blueberry linkage map was collinear with cranberry, while the remaining 7% (66.3 cM) was spread across 15 non-collinear regions detected in eight of the 12 linkage groups. These observations suggest that large-scale genome differentiation between the cranberry and blueberry genomes has not occurred during their evolution, and that sequence information will be highly transferable between the species in future genetic research and breeding. Finally, the set of 323 cross-transferable SSRs and linkage maps they were used to construct can serve as a shared resource for the Vaccinium research community, enabling additional comparative mapping studies, the identification and transfer of quantitative trait loci and candidate genes between species, and future exploration of evolutionary relationships in Vaccinium. 相似文献
993.
994.
995.
Effect of Cecropin B and a Synthetic Analogue on Propagation of Fish Viruses In Vitro 总被引:2,自引:0,他引:2
Abstract Cecropins and other natural antimicrobial peptides are widely distributed in animals from insects to mammals. These
proteins have been shown to be major constituents of the innate immune systems of animals for nonspecific defense of the host
against various bacteria and parasites. Therefore, exploitation of this natural innate defense system may lead to the development
of effective methods for protecting fish from invasion by microbial pathogens. Recently, we have demonstrated that the introduction
of cecropin transgenes into Japanese medaka (Oryzias latipes) conferred resistance to infection by fish bacterial pathogens.
Aside from a few reports documenting the antiviral effect of antimicrobial peptides including cecropins against mammalian
viruses, there is no evidence for the effect of these peptides against fish viruses. In this article we present results of
in vitro characterization of native cecropin B and a synthetic analogue, CF17, against several important fish viral pathogens—namely,
infectious hematopoietic necrosis virus (IHNV), viral hemorrhagic septicemia virus (VHSV), snakehead rhabdovirus (SHRV), and
infectious pancreatic necrosis virus (IPNV). Upon coincubation of these peptides and viruses, the viral titers yielded in
fish cells were reduced from several fold to 104-fold. Direct disruption of the viral envelope and disintegration of the viral
capsids may be involved in the inhibition of viral replication by the peptides. Results of our studies demonstrate the potential
of manipulating antimicrobial peptide genes by transgenesis to combat viral infection in fish. 相似文献
996.
997.
998.
José David Flores-Félix Luis R. Silva Lina P. Rivera Marta Marcos-García Paula García-Fraile Eustoquio Martínez-Molina Pedro F. Mateos Encarna Velázquez Paula Andrade Raúl Rivas 《PloS one》2015,10(4)
The increasing interest in the preservation of the environment and the health of consumers is changing production methods and food consumption habits. Functional foods are increasingly demanded by consumers because they contain bioactive compounds involved in health protection. In this sense biofertilization using plant probiotics is a reliable alternative to the use of chemical fertilizers, but there are few studies about the effects of plant probiotics on the yield of functional fruits and, especially, on the content of bioactive compounds. In the present work we reported that a strain of genus Phyllobacterium able to produce biofilms and to colonize strawberry roots is able to increase the yield and quality of strawberry plants. In addition, the fruits from plants inoculated with this strain have significantly higher content in vitamin C, one of the most interesting bioactive compounds in strawberries. Therefore the use of selected plant probiotics benefits the environment and human health without agronomical losses, allowing the production of highly functional foods. 相似文献
999.
Dental markers have been used to unravel particularities of paleodiet, subsistence, social structure, and health. This article aims to compare oral pathology among four pre‐Columbian groups with different degrees of agricultural and socio‐cultural development but comparable ecological conditions who lived on the coastal desert of Peru. Three of these groups are assigned to distinct phases of the Formative Period (2500–1 BC), a time critical for our understanding of the development of agriculture and social complexity. The fourth group corresponds to the Late Intermediate Period (1000–1470 AD), when agriculture had its apogee and society was highly stratified. In this study we test whether there is an increase (1) in the frequency of carious lesions and (2) in caries depth, and (3) if there is a shift from occlusal to extra‐occlusal caries locations with the development of agriculture. Therefore, we analyze the frequencies of carious lesions and antemortem tooth loss (AMTL), the caries distributions by age, sex, and type of tooth, as well as the tissues affected by, and the location of the carious lesions. Since there are no significant differences in the frequencies of carious lesions and AMTL between the groups, we reject hypothesis 1. In contrast, caries depth does increase, and caries location changes from occlusal to extra‐occlusal sites with agricultural development. However, we can only corroborate hypothesis 2 and 3 when taking into consideration dental wear. Thus, we recommend that caries depth and locations should be used with evaluations of dental wear to reconstruct subsistence in ancient populations. Am J Phys Anthropol 143:75–91, 2010. © 2010 Wiley‐Liss, Inc. 相似文献
1000.
Kamtekar S Berman AJ Wang J Lázaro JM de Vega M Blanco L Salas M Steitz TA 《Molecular cell》2004,16(4):609-618
The DNA polymerase from phage phi29 is a B family polymerase that initiates replication using a protein as a primer, attaching the first nucleotide of the phage genome to the hydroxyl of a specific serine of the priming protein. The crystal structure of phi29 DNA polymerase determined at 2.2 A resolution provides explanations for its extraordinary processivity and strand displacement activities. Homology modeling suggests that downstream template DNA passes through a tunnel prior to entering the polymerase active site. This tunnel is too small to accommodate double-stranded DNA and requires the separation of template and nontemplate strands. Members of the B family of DNA polymerases that use protein primers contain two sequence insertions: one forms a domain not previously observed in polymerases, while the second resembles the specificity loop of T7 RNA polymerase. The high processivity of phi29 DNA polymerase may be explained by its topological encirclement of both the downstream template and the upstream duplex DNA. 相似文献