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排序方式: 共有433条查询结果,搜索用时 171 毫秒
411.
K Lohmann 《Histochemistry》1979,63(1):47-56
During early development of Triturus vulgaris, as a measure for nuclear activity in neuroectoderm, mesoderm and endoderm, nuclear RNA content was determined by cytochemical methods. In the first stages of gastrulation, that is to say during the early phase of neural induction, the RNA content of the inducing system is considerably higher than in the reacting system. Then, with a phase-shift of about 10 h, the RNA content of the neuroectoderm increases quickly also. In the following stages the nuclear RNA content of both regions is reduced. A second continuous increase in the RNA amount coincides with the formation of the neural tube. In the mesoderm, enhancement of RNA content correlates with cytodifferentiation of the chorda. In all stages the RNA content of the endoderm is higher than in the other tissues and it becomes successively diminished from the early gastrula to the tailbud stage. 相似文献
412.
The selfassociation of N6,N9-dimethyladenine and N6-dimethyl-N9-ethyladenine has been studied by means of NMR technique. The thermodynamic quantities have been calculated using an isodesmic NMR model with three NMR parameters (the monomer shift deltaM and two complex shifts delta2 and delta3). The dependence of the thermodynamic quantities on the NMR parameters is discussed. Special attention is given to the determination of deltaM and its temperature dependence. Calculations with delta3 = 2 - delta2 and deltaM taken independently of temperature result in an average entropy deltaS = - 17.9 +/- 1.8 e.u. for N6,N9-dimethyladenine and deltaS = - 16.7 +/- 1.7 e.u. for N6-dimethyl-N9-ethyladenine and in an average enthalpy deltaH = - 7.2 +/- 0.6 kcal - mol-1 for both substances investigated. 相似文献
413.
The accurate analyses of massive amounts of data obtained through next‐generation sequencing depend on the selection of appropriate evolutionary models. Many plastid phylogenomic studies typically analyze plastome data as a single partition, or divided by a region, using a concatenate “supergene” approach. The effects of molecular evolutionary models and character partition strategies on plastome‐based phylogenies have generally been evaluated at higher taxonomic levels in green plants. Using plastome data from 32 species of Amphilophium, a genus of Neotropical lianas, we explored potential sources of topological incongruence with different plastid genome datasets and approaches. Specifically, we evaluated the effects of compositional heterogeneity, codon usage bias, positive selection, and incomplete lineage sorting as sources of systematic error (i.e., the recovery of well‐supported conflicting topologies). We compared different datasets (e.g., non‐coding regions, exons, and codon‐aligned and translated amino acids) using concatenated approaches under site‐heterogeneous and site‐homogeneous models, as well as multispecies coalescent (MSC) methods. We found incongruences in recovered phylogenetic relationships, which were mainly located in short internodes. The MSC and concatenated approaches recovered similar topologies. The analysis of GC content and codon usage bias indicated higher substitution rates and AT excess at the third codon positions, and we found evidence of positive selection in 3% of amino acid sites. There were no significant differences among species in site biochemical profiles. We argue that the selection of appropriate partition strategies and evolutionary models is important to increase accuracy in phylogenetic relationships, even when using plastome datasets, which is still the primarily used genome in plant phylogenetics. 相似文献
414.
Roger Ivar Lohmann 《Anthropological Forum》2003,13(2):175-185
This article does not have an abstract 相似文献
415.
416.
J. Pukinski Melekper Öktay Otto Jost Michael Lohmann Ekkehard Jeserich und Herbert Ringleben 《Journal of Ornithology》1967,108(3):346-354
Ohne Zusammenfassung 相似文献
417.
Matthew J. Fuxjager Kyla R. Davidoff Lisa A. Mangiamele Kenneth J. Lohmann 《Proceedings. Biological sciences / The Royal Society》2014,281(1791)
Loggerhead sea turtle hatchlings (Caretta caretta) use regional magnetic fields as open-ocean navigational markers during trans-oceanic migrations. Little is known, however, about the ontogeny of this behaviour. As a first step towards investigating whether the magnetic environment in which hatchlings develop affects subsequent magnetic orientation behaviour, eggs deposited by nesting female loggerheads were permitted to develop in situ either in the natural ambient magnetic field or in a magnetic field distorted by magnets placed around the nest. In orientation experiments, hatchlings that developed in the normal ambient field oriented approximately south when exposed to a field that exists near the northern coast of Portugal, a direction consistent with their migratory route in the northeastern Atlantic. By contrast, hatchlings that developed in a distorted magnetic field had orientation indistinguishable from random when tested in the same north Portugal field. No differences existed between the two groups in orientation assays involving responses to orbital movements of waves or sea-finding, neither of which involves magnetic field perception. These findings, to our knowledge, demonstrate for the first time that the magnetic environment present during early development can influence the magnetic orientation behaviour of a neonatal migratory animal. 相似文献
418.
Prof. Dr. D. Lohmann 《Medizinische Genetik》2007,19(2):229-233
Ocular neoplasms are associated with several hereditary cancer predisposition syndromes. Of these, hereditary retinoblastoma is the most important. Historically, hereditary retinoblastoma has been the prototype dominant cancer predisposition, and Knudson’s study of this tumour has resulted in the two-step mutation hypothesis, which has been seminal for developing a further understanding of hereditary cancers. Although ocular manifestations are of minor relevance for the prognosis in tumour syndromes other than retinoblastoma, they may be important for the recognition of the underlying cancer predisposition. There is no monogenic predisposition for the development of uveal melanoma, which is the most frequent malignant ocular neoplasm in humans. However, epidemiological data suggest that genetic factors may play a role. The study of somatic alterations in these tumours has shown that the loss of one chromosome 3 is closely associated with an adverse prognosis. Such a somatic genotype-phenotype association is highly exceptional among solid tumours. 相似文献
419.
Katrin Domsch Julia Schröder Matthias Janeschik Christoph Schaub Ingrid Lohmann 《Cell reports》2021,34(1):108577
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420.