全文获取类型
收费全文 | 3475篇 |
免费 | 432篇 |
国内免费 | 17篇 |
出版年
2021年 | 37篇 |
2017年 | 28篇 |
2016年 | 40篇 |
2015年 | 64篇 |
2014年 | 80篇 |
2013年 | 121篇 |
2012年 | 148篇 |
2011年 | 161篇 |
2010年 | 96篇 |
2009年 | 109篇 |
2008年 | 135篇 |
2007年 | 154篇 |
2006年 | 130篇 |
2005年 | 149篇 |
2004年 | 138篇 |
2003年 | 131篇 |
2002年 | 129篇 |
2001年 | 82篇 |
2000年 | 103篇 |
1999年 | 85篇 |
1998年 | 52篇 |
1997年 | 46篇 |
1996年 | 41篇 |
1995年 | 53篇 |
1994年 | 46篇 |
1993年 | 38篇 |
1992年 | 62篇 |
1991年 | 71篇 |
1990年 | 40篇 |
1989年 | 52篇 |
1988年 | 52篇 |
1987年 | 49篇 |
1986年 | 49篇 |
1985年 | 62篇 |
1984年 | 56篇 |
1983年 | 58篇 |
1982年 | 58篇 |
1981年 | 40篇 |
1980年 | 40篇 |
1979年 | 45篇 |
1978年 | 38篇 |
1977年 | 39篇 |
1976年 | 45篇 |
1975年 | 33篇 |
1974年 | 37篇 |
1973年 | 44篇 |
1971年 | 33篇 |
1970年 | 32篇 |
1969年 | 31篇 |
1968年 | 39篇 |
排序方式: 共有3924条查询结果,搜索用时 328 毫秒
101.
102.
Field measures of tree and shrub dimensions were used with established biomass equations in a stratified, two-stage cluster sampling design to estimate above-ground ovendry woody biomass and carbon storage of the eastern deciduous forest of North America. Biomass averaged 8.1 ± 1.4 (95% C.I.) kg/m2 and totaled 18.1 ± 3.1 (95% C.I.) gigatons. Carbon storage averaged 3.6 ± 0.6 (95% C.I.) kg/m2 and totaled 8.1 ± 1.4 (95% C.I.) gigatons. These values are lower than previous estimates commonly used in the analysis of the global carbon budget which range from 17.1 to 23.1 kg/m2 for biomass and 7.7 to 10.4 kg/m2 for carbon storage. These new estimates for the deciduous forest, together with earlier work in the boreal forest begin to reveal a pattern of overestimation of global carbon storage by vegetation in analyses of the global carbon budget. We discuss reasons for the differences between the new and earlier estimates, as well as implications for our understanding of the global carbon cycle. 相似文献
103.
104.
105.
Roles of the GLABROUS1 and TRANSPARENT TESTA GLABRA Genes in Arabidopsis Trichome Development 总被引:11,自引:5,他引:6
下载免费PDF全文
![点击此处可从《The Plant cell》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Arabidopsis trichomes are branched, single-celled epidermal hairs. These specialized cells provide a convenient model for investigating the specification of cell fate in plants. Two key genes regulating the initiation of trichome development are GLABROUS1 (GL1) and TRANSPARENT TESTA GLABRA (TTG). GL1 is a member of the myb gene family. The maize R gene, which can functionally complement the Arabidopsis ttg mutation, encodes a basic helix-loop-helix protein. We used constitutively expressed copies of the GL1 and R genes to test hypotheses about the roles of GL1 and TTG in trichome development. The results support the hypothesis that TTG and GL1 cooperate at the same point in the trichome developmental pathway. Furthermore, the constitutive expression of both GL1 and R in the same plant caused trichomes to develop on all shoot epidermal surfaces. Results were also obtained indicating that TTG plays an additional role in inhibiting neighboring cells from becoming trichomes. 相似文献
106.
107.
108.
Vladimir Vartanian Jocelyn F. Krey Paroma Chatterjee Allison Curtis Makayla Six Sean P. M. Rice Sherri M. Jones Harini Sampath Charles N. Allen Renee C. Ryals R. Stephen Lloyd Peter G. Barr-Gillespie 《Genes, Brain & Behavior》2023,22(4):e12849
Relationships between novel phenotypic behaviors and specific genetic alterations are often discovered using target-specific, directed mutagenesis or phenotypic selection following chemical mutagenesis. An alternative approach is to exploit deficiencies in DNA repair pathways that maintain genetic integrity in response to spontaneously induced damage. Mice deficient in the DNA glycosylase NEIL1 show elevated spontaneous mutations, which arise from translesion DNA synthesis past oxidatively induced base damage. Several litters of Neil1 knockout mice included animals that were distinguished by their backwards-walking behavior in open-field environments, while maintaining frantic forward movements in their home cage environment. Other phenotypic manifestations included swim test failures, head tilting and circling. Mapping of the mutation that conferred these behaviors showed the introduction of a stop codon at amino acid 4 of the Ush1g gene. Ush1gbw/bw null mice displayed auditory and vestibular defects that are commonly seen with mutations affecting inner-ear hair-cell function, including a complete lack of auditory brainstem responses and vestibular-evoked potentials. As in other Usher syndrome type I mutant mouse lines, hair cell phenotypes included disorganized and split hair bundles, as well as altered distribution of proteins for stereocilia that localize to the tips of row 1 or row 2. Disruption to the bundle and kinocilium displacement suggested that USH1G is essential for forming the hair cell's kinocilial links. Consistent with other Usher type 1 models, Ush1gbw/bw mice had no substantial retinal degeneration compared with Ush1gbw/+ controls. In contrast to previously described Ush1g alleles, this new allele provides the first knockout model for this gene. 相似文献
109.
Taffet George E.; Michael Lloyd A.; Tate Charlotte A. 《Journal of applied physiology》1996,81(4):1488-1494
Taffet, George E., Lloyd A. Michael, and Charlotte A. Tate.Exercise training improves lusitropy by isoproterenol in papillarymuscles from aged rats. J. Appl.Physiol. 81(4): 1488-1494, 1996.Aging isassociated with a decreased cardiac responsiveness to -adrenergicstimulation. We examined the effect of endurance exercise training ofold Fischer 344 male rats on -adrenergic stimulation of the functionof isolated left ventricular papillary muscle. Three groups wereexamined: sedentary mature (SM; 12-mo old), sedentary old (SO;23-24 mo old), and exercised old (EO; 23-24 mo old) that weretreadmill trained for 4-8 wk. The isometric contractile propertieswere studied at 0.2 Hz and 0.75 mM calcium. Without -adrenergicstimulation, there were no group differences for peak tension, maximumrate of tension development(+dP/dt), or maximum rateof tension dissipation(dP/dt). The time to peak tension was longer (P < 0.05) forboth EO and SO than for SM rats. Half relaxation time(RT1/2) was prolonged(P < 0.05) for SO compared with SMand EO (which did not differ). The three groups did not differ in the-adrenergic stimulation by isoproterenol of peak tension,dP/dt, time to peak tension, orcontraction duration. The inotropic response(+dP/dt) of SM was greater(P < 0.05) than that in SO or EOrats (which did not differ); however, the lusitropic response(RT1/2) was lesser(P < 0.05) in SO than in SM or EO rats (which did not differ). Thus exercise training of old rats improved the lusitropic response to isoproterenol without altering theage-associated impairment in inotropic response. 相似文献
110.