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Cell and chloroplast structural changes in palisade cells from mature leaves of Brassica napus L. cv. Paroll were quantified following exposure of plants to enhanced ultraviolet-B (280–320 nm; 13 kJ m?2 day?1 biologically effective UV-B) radiation at two different levels of photosynthetically active radiation (PAR, 400–700 nm; 200 and 700 μmol m?2 s?1). Short-term changes in leaf ultrastructure after 30 min and longer term changes after one day and one week were analyzed using stereological techniques incorporating light and electron microscopy and mathematical reconstruction of a mean cell for each sample. Ultraviolet-B together with either relatively high or low PAR resulted in cell structural changes resembling those typical of plants under shade conditions, with the most marked response occurring after 30 min of UV-B radiation. The ultrastructural changes at the cellular level were generally similar in both the relatively high and low PAR plus UV-B radiation treatments. The surface areas of all three thylakoid types, the appressed, non-appressed and margin thylakoids increased in the palisade tissue under supplemental UV-B irradiation. Although the appressed and non-appressed thylakoids increased in surface area, they did not increase equally, leaving open the possibility that the two thylakoid types have independent regulatory systems or different sensitivity to UV-B radiation. Increased thylakoid packing (mm2 thylakoid membrane per mm2 leaf surface) in UV-B-exposed plants may increase the statistical probability of photon interception. An increased level of UV-absorbing pigments after one week of supplemental UV-B radiation did not prevent or significantly ameliorate UV effects. Our data supported the assumption that UV-B radiation may have a regulatory role besides damaging effects and that an increased UV-B environment will likely increase this regulatory influence of UV-B radiation. 相似文献
475.
Christina Halgren Nete M. Nielsen Lusine Nazaryan-Petersen Asli Silahtaroglu Ryan L. Collins Chelsea Lowther Susanne Kjaergaard Morten Frisch Maria Kirchhoff Karen Brøndum-Nielsen Allan Lind-Thomsen Yuan Mang Zahra El-Schich Claire A. Boring Mana M. Mehrjouy Peter K.A. Jensen Christina Fagerberg Lotte N. Krogh Iben Bache 《American journal of human genetics》2018,102(6):1090-1103
476.
Inferences of genetic architecture of bill morphology in house sparrow using a high‐density SNP array point to a polygenic basis 下载免费PDF全文
Sarah L. Lundregan Ingerid J. Hagen Jostein Gohli Alina K. Niskanen Petri Kemppainen Thor Harald Ringsby Thomas Kvalnes Henrik Pärn Bernt Rønning Håkon Holand Peter S. Ranke Anna S. Båtnes Linn‐Karina Selvik Sigbjørn Lien Bernt‐Erik Sæther Henrik Jensen 《Molecular ecology》2018,27(17):3498-3514
Understanding the genetic architecture of quantitative traits can provide insights into the mechanisms driving phenotypic evolution. Bill morphology is an ecologically important and phenotypically variable trait, which is highly heritable and closely linked to individual fitness. Thus, bill morphology traits are suitable candidates for gene mapping analyses. Previous studies have revealed several genes that may influence bill morphology, but the similarity of gene and allele effects between species and populations is unknown. Here, we develop a custom 200K SNP array and use it to examine the genetic basis of bill morphology in 1857 house sparrow individuals from a large‐scale, island metapopulation off the coast of Northern Norway. We found high genomic heritabilities for bill depth and length, which were comparable with previous pedigree estimates. Candidate gene and genomewide association analyses yielded six significant loci, four of which have previously been associated with craniofacial development. Three of these loci are involved in bone morphogenic protein (BMP) signalling, suggesting a role for BMP genes in regulating bill morphology. However, these loci individually explain a small amount of variance. In combination with results from genome partitioning analyses, this indicates that bill morphology is a polygenic trait. Any studies of eco‐evolutionary processes in bill morphology are therefore dependent on methods that can accommodate polygenic inheritance of the phenotype and molecular‐scale evolution of genetic architecture. 相似文献
477.
Christos Karampelias Jérémie Charbord Agneta Hilding Linn Rautio Philippe Bertolino Claes‐Göran Östenson Kerstin Brismar Olov Andersson 《The EMBO journal》2016,35(18):2026-2044
There is great interest in therapeutically harnessing endogenous regenerative mechanisms to increase the number of β cells in people with diabetes. By performing whole‐genome expression profiling of zebrafish islets, we identified 11 secreted proteins that are upregulated during β‐cell regeneration. We then tested the proteins'' ability to potentiate β‐cell regeneration in zebrafish at supraphysiological levels. One protein, insulin‐like growth factor (Igf) binding‐protein 1 (Igfbp1), potently promoted β‐cell regeneration by potentiating α‐ to β‐cell transdifferentiation. Using various inhibitors and activators of the Igf pathway, we show that Igfbp1 exerts its regenerative effect, at least partly, by inhibiting Igf signaling. Igfbp1''s effect on transdifferentiation appears conserved across species: Treating mouse and human islets with recombinant IGFBP1 in vitro increased the number of cells co‐expressing insulin and glucagon threefold. Moreover, a prospective human study showed that having high IGFBP1 levels reduces the risk of developing type‐2 diabetes by more than 85%. Thus, we identify IGFBP1 as an endogenous promoter of β‐cell regeneration and highlight its clinical importance in diabetes. 相似文献
478.
Kausrud KL Viljugrein H Frigessi A Begon M Davis S Leirs H Dubyanskiy V Stenseth NC 《Proceedings. Biological sciences / The Royal Society》2007,274(1621):1963-1969
In central Asia, the great gerbil (Rhombomys opimus) is the main host for the bacterium Yersinia pestis, the cause of bubonic plague. In order to prevent plague outbreaks, monitoring of the great gerbil has been carried out in Kazakhstan since the late 1940s. We use the resulting data to demonstrate that climate forcing synchronizes the dynamics of gerbils over large geographical areas. As it is known that gerbil densities need to exceed a threshold level for plague to persist, synchrony in gerbil abundance across large geographical areas is likely to be a condition for plague outbreaks at similar large scales. Here, we substantiate this proposition through autoregressive modelling involving the normalized differentiated vegetation index as a forcing covariate. Based upon predicted climate changes, our study suggests that during the next century, plague epizootics may become more frequent in central Asia. 相似文献
479.
Nygren-Babol L 《Bioscience reports》2007,27(6):413-4; author reply 414-7
480.
Extreme large body size is rare in modern Zygoptera (damselflies). Only the South and Central American damselfly family Pseudostigmatidae and one African species, Coryphagrion grandis, share the morphological trait of gigantism. By means of phylogenetic analyses using two mitochondrial markers (16S rDNA and ND1) and one nuclear marker (EF1) in combination with an existing morphological data set, we trace the evolution of gigantism in damselflies. Individual and combined data sets were analyzed using the maximum parsimony, minimum evolution and maximum likelihood algorithms. Regardless of the algorithm used and the data set analyzed all principal tree topologies support a monophyly of the damselfly taxa displaying giant body size. This supports the view that the evolution of gigantism in damselflies from Africa and South America is not the result of convergent evolution due to strikingly similar habitat preferences, but rather the result of close genealogical relationship. Because modern odonates evolved before the split of Africa from Gondwanaland, the proposed phylogeny suggests that C. grandis represents a Gondwana relict. 相似文献