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991.
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The activity of superoxide dismutase (SOD) from bovine erythrocytes was measured by the inhibition of nitrotetrazolium blue reduction rate in superoxide anion radical generation systems--xanthine/xanthine oxidase of NADH/phenazine methasulfate. The enzyme activity increases in the presence of compounds acting as electron donors in radical-involving reactions and decreased in the presence of compounds possessing the properties of electron acceptors. Activation of SOD by electron donors and its inhibition by electron acceptors was dependent on the concentration of the above compounds. In the absence of SOD electron donors and acceptors did not change the rate of tetrazolium blue reduction by superoxide anion radicals. The role of the new type of SOD regulation for the enzyme functioning in the cell is discussed. 相似文献
995.
A comparison of liquid-holding recovery and photoreactivation in halophilic and non-halophilic bacteria 总被引:2,自引:0,他引:2
The ability of the extreme halophile Halobacterium cutirubrum to recover from the effects of ultraviolet radiation during liquid holding in the dark in non-nutrient medium has been compared with that of (i) a moderately halophilic bacterium (NRC 41227) and (ii) Escherichia coli B. The photoreactivabilities of all three bacteria have also been studied. The extreme halophile was incapable of liquid-holding recovery in these conditions, in marked contrast to both E. coli B and the moderate halophile, and also failed to recover when held in nutrient medium in the dark. These results strongly support the hypothesis that H. cutirubrum lacks DNA excision repair. It was also found that ultraviolet-irradiated H. cutirubrum could be almost completely photoreactivated from any level of survival in the range 10(-4)-80%, provided exposure to visible light was not delayed, whereas the moderate halophile resembled E. coli B and had a comparatively limited capacity for photoreactivation. 相似文献
996.
Eberhard Gischler 《Facies》2010,56(2):173-177
Shallow fore-reef areas worldwide are usually characterized by spurs and grooves. A comparison of examples from the three
world oceans suggests that Indo-Pacific spurs and grooves are shaped predominantly by erosion, whereas western Atlantic spur
and groove systems are largely a product of constructive processes. I propose that this difference is caused by regional differences
in Holocene sea-level change, which controlled exposure to waves and currents, and reef-accretion rates. The transgressive–regressive
sea-level curve in the Indo-Pacific realm, i.e., the Mid-to-Late Holocene sea-level fall in these areas has maintained high-energy
conditions in the shallow fore reef. Higher exposure to waves and currents favors erosion and leads to a dominance of crustose
coralline algae that have relatively slow growth rates. In the western Atlantic, the transgressive Holocene sea level has
caused Mid-to-Late Holocene deepening and has maintained accommodation space for reef accretion. Fast-growing acroporid corals
thrive under lower exposure and are more common than coralline algae. The fossil record of the spur and groove system is rather
poor, which is probably a consequence of the need of excellent, three-dimensional outcrops for identification. 相似文献
997.
T P Chernobel' T I Randmaa Z Ia Maksimova A A Shinkorenko V N Migunov 《Zhurnal mikrobiologii, epidemiologii, i immunobiologii》1987,(11):88-90
A total of 218 batches of blood preparations produced from different raw materials have been studied by means of enzyme immunoassay kits (Abbott Laboratories, USA). The assays have revealed that the preparations under study are nonstandard with respect to the content and isolation rate of HBsAg, the marker of hepatitis B virus. These data necessitate search for the ways of improving the quality of blood preparations. 相似文献
998.
E S Revazova Iu N Solov'ev T M Khizhniakova T V Iudicheva 《Biulleten' eksperimental'no? biologii i meditsiny》1985,99(4):469-471
The authors describe human cancer strains established from 6 cell lines transplanted to nude mice and rats: cancer of the liver, colon, lung, bladder and Burkitt's lymphoma. In spite of a long history (for several years) of cell line transfers in vitro, on transplantation of tumor cells, nude animals established tumors histologically identical to the primary cancer. 相似文献
999.
1000.
Immunotherapy of lymphoid and nonlymphoid tumors with monoclonal anti-Lyt-1 antibodies 总被引:1,自引:0,他引:1
N Hollander 《Journal of immunology (Baltimore, Md. : 1950)》1984,133(5):2801-2805
Monoclonal antibodies against the T cell differentiation antigen Lyt-1 were effective in the therapy of transplanted mouse tumors. A possible mechanism whereby anti-Lyt-1 antibodies directly bind and affect the tumor cells was excluded by the following findings: a) growth of lymphoid and nonlymphoid tumors (which lack Lyt-1 antigen) was affected by anti-Lyt-1 antibodies; and b) the curative effect of passively administered anti-Lyt-1 anti-bodies was abrogated in mice depleted of T cells, supporting a mechanism whereby host Lyt-1+ cells were involved in tumor therapy. Treatment with anti-Lyt-1 antibodies was not accompanied by depletion of Lyt-1+ cells from lymphoid organs, indicating that the administered antibodies altered Lyt-1+ cell functions without affecting their frequency. In view of the in vitro enhancing effects of anti-Lyt-1 antibodies on a variety of immune responses (including lymphokine secretion and generation of cytotoxic T cell), it is suggested that the potentiation of Lyt-1+ cell activity by passively administered anti-Lyt-1 antibodies results in tumor rejection. 相似文献