全文获取类型
收费全文 | 15852篇 |
免费 | 1387篇 |
国内免费 | 1607篇 |
专业分类
18846篇 |
出版年
2024年 | 37篇 |
2023年 | 225篇 |
2022年 | 579篇 |
2021年 | 877篇 |
2020年 | 660篇 |
2019年 | 750篇 |
2018年 | 715篇 |
2017年 | 527篇 |
2016年 | 678篇 |
2015年 | 1002篇 |
2014年 | 1155篇 |
2013年 | 1286篇 |
2012年 | 1540篇 |
2011年 | 1290篇 |
2010年 | 795篇 |
2009年 | 760篇 |
2008年 | 825篇 |
2007年 | 694篇 |
2006年 | 604篇 |
2005年 | 553篇 |
2004年 | 401篇 |
2003年 | 399篇 |
2002年 | 358篇 |
2001年 | 244篇 |
2000年 | 208篇 |
1999年 | 238篇 |
1998年 | 134篇 |
1997年 | 147篇 |
1996年 | 138篇 |
1995年 | 121篇 |
1994年 | 117篇 |
1993年 | 89篇 |
1992年 | 97篇 |
1991年 | 74篇 |
1990年 | 82篇 |
1989年 | 61篇 |
1988年 | 60篇 |
1987年 | 43篇 |
1986年 | 50篇 |
1985年 | 50篇 |
1984年 | 33篇 |
1983年 | 21篇 |
1982年 | 22篇 |
1981年 | 11篇 |
1980年 | 10篇 |
1979年 | 16篇 |
1978年 | 6篇 |
1977年 | 12篇 |
1976年 | 9篇 |
1973年 | 9篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
881.
The unique physicochemical properties of (2D) nanomaterials make them well‐suited for use in sustainable energy applications. Many of these materials can be further improved with vacancy engineering. This review details recent progress in the vacancy engineering of ultrathin 2D nanomaterials. For clarity, it mainly focuses on various ultrathin 2D materials in three categories: Xa&XaYb‐, MaXb‐, or MaXbYc‐structured materials. Recently developed vacancies in different types of ultrathin 2D materials, as well as their preparation and characterization, are described. Emphasis is placed on the potential electrochemical energy storage and conversion applications of these materials. This review considers the relationship between vacancy properties and material categories of various ultrathin 2D materials in terms of application requirements, preparation, and characterization techniques. The challenges and future outlook of this promising field are summarized. 相似文献
882.
883.
Ming‐Ming Guo Wen‐Long Wang Hong‐Liang Kang Bo Yang Jian‐Ming Li 《Restoration Ecology》2020,28(1):104-114
Revegetation represents an effective measure for preventing soil erosion on the Loess Plateau. However, the effects of revegetation‐induced changes in soil and root properties on soil resistance to concentrated flow erosion (SRC) remain unclear. This study sampled soils and roots across a 25‐year chronosequence from farmland to grasslands of different ages (3, 7, 10, 18, and 25 years) to quantify variations in soil and root properties (soil bulk density, SBD; soil disintegration rate, SDR; saturated hydraulic conductivity, SHC; organic matter content, OMC; water‐stable aggregate, WSA; mean weight diameter, MWD; root mass density, RMD; root length density, RLD; and root surface area density, RSAD) and their effects on SRC. Farmland and grassland SRCs were obtained using a hydraulic flume. Soil properties and root density gradually improved with restoration time. In terms of the comprehensive soil property index calculated via principal component analysis, grassland values were 0.66 to 1.94 times greater than farmland values. Grassland SRCs increased and gradually stabilized (>18 years) over time and were 1.60 to 8.26 times greater than farmland SRC. SRC improvement was significantly related to increases in OMC, SHC, WSA, and MWD and decreases in SBD and SDR over time. SRC was effectively simulated by the Hill curve of RMD, RLD, and RSAD. SDR, SHC, and RMD (0.5–1.0 mm) affected SRC the most. This study scientifically describes how revegetation improves soil quality and soil resistance to flow erosion, and suggests that vegetations rich in 0.5–1.0 mm roots should be preferred during revegetation. 相似文献
884.
885.
886.
887.
HW Gao LP Wang S Liang YX Liu SL Tong JJ Wang YP Li XF Wang H Yang JQ Ma LQ Fang WC Cao 《PloS one》2012,7(8):e43686
Malaria is re-emerging in Anhui Province, China after a decade long’ low level of endemicity. The number of human cases has increased rapidly since 2000 and reached its peak in 2006. That year, the malaria cases accounted for 54.5% of total cases in mainland China. However, the spatial and temporal patterns of human cases and factors underlying the re-emergence remain unclear. We established a database containing 20 years’ (1990–2009) records of monthly reported malaria cases and meteorological parameters. Spearman correlations were used to assess the crude association between malaria incidence and meteorological variables, and a polynomial distributed lag (PDL) time-series regression was performed to examine contribution of meteorological factors to malaria transmission in three geographic regions (northern, mid and southern Anhui Province), respectively. Then, a two-year (2008–2009) prediction was performed to validate the PDL model that was created by using the data collected from 1990 to 2007. We found that malaria incidence decreased in Anhui Province in 1990s. However, the incidence has dramatically increased in the north since 2000, while the transmission has remained at a relatively low level in the mid and south. Spearman correlation analyses showed that the monthly incidences of malaria were significantly associated with temperature, rainfall, relative humidity, and the multivariate El Niño/Southern Oscillation index with lags of 0–2 months in all three regions. The PDL model revealed that only rainfall with a 1–2 month lag was significantly associated with malaria incidence in all three regions. The model validation showed a high accuracy for the prediction of monthly incidence over a 2-year predictive period. Malaria epidemics showed a high spatial heterogeneity in Anhui Province during the 1990–2009 study periods. The change in rainfall drives the reemergence of malaria in the northern Anhui Province. 相似文献
888.
Shi G Shaw G Liang YH Subburaman P Li Y Wu Y Yan H Ji X 《Bioorganic & medicinal chemistry》2012,20(1):47-57
6-Hydroxymethyl-7,8-dihydropterin pyrophosphokinase (HPPK), a key enzyme in the folate biosynthetic pathway, catalyzes the pyrophosphoryl transfer from ATP to 6-hydroxymethyl-7,8-dihydropterin. The enzyme is essential for microorganisms, is absent from humans, and is not the target for any existing antibiotics. Therefore, HPPK is an attractive target for developing novel antimicrobial agents. Previously, we characterized the reaction trajectory of HPPK-catalyzed pyrophosphoryl transfer and synthesized a series of bisubstrate analog inhibitors of the enzyme by linking 6-hydroxymethylpterin to adenosine through 2, 3, or 4 phosphate groups. Here, we report a new generation of bisubstrate analog inhibitors. To improve protein binding and linker properties of such inhibitors, we have replaced the pterin moiety with 7,7-dimethyl-7,8-dihydropterin and the phosphate bridge with a piperidine linked thioether. We have synthesized the new inhibitors, measured their K(d) and IC(50) values, determined their crystal structures in complex with HPPK, and established their structure-activity relationship. 6-Carboxylic acid ethyl ester-7,7-dimethyl-7,8-dihydropterin, a novel intermediate that we developed recently for easy derivatization at position 6 of 7,7-dimethyl-7,8-dihydropterin, offers a much high yield for the synthesis of bisubstrate analogs than that of previously established procedure. 相似文献
889.
Liang Zhao Miaochun FanDehui Zhang Ruiping YangFeilong Zhang Lin XuXiuli Wei Yaoyao ShenGehong Wei 《Systematic and applied microbiology》2014
A total of 155 nodule isolates that originated from seven sites in Northwest China were characterized by PCR-RFLP of the 16S rRNA gene and sequence analysis of multiple core genes (16S rRNA, recA, atpD, and glnII) in order to investigate the diversity and biogeography of Glycine soja-nodulating rhizobia. Among the isolates, 80 were Ensifer fredii, 19 were Ensifer morelense, 49 were Rhizobium radiobacter, and 7 were putative novel Rhizobium species. The phylogenies of E. fredii and E. morelense isolates in a concatenate tree (assembly of all housekeeping genes) were generally consistent with those in individual gene trees. However, incongruence was found in the phylogenies of the different genes of Rhizobium isolates, indicating that lateral transfer or recombination possibly occurred in these gene loci. Despite their species identity, all the isolates in this study formed a single lineage related to E. fredii in nodAand nifH gene phylogenies, which also indicated that the symbiotic genes were laterally transferred between different species. Biogeographic patterns were found at the species and strain genomic type levels, as revealed by BOXA1R fingerprinting, demonstrating that the evolution of rhizobial populations in different geographic locations was related to soil types, altitude and spatial effects. This study is the first to report that E. morelense, R. radiobacter, and Rhizobium sp. are microsymbionts of G. soja, as well as showing that the diversity of G. soja rhizobia is enhanced and new rhizobia have evolved in Northwest China. 相似文献
890.