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841.
We tested whether differences in ploidy level and previous exposure to herbivory can affect plant tolerance to herbivory.
We conducted a common garden experiment with 12 populations of two ploidy levels of the perennial herb Cardamine
pratensis (five populations of tetraploid ssp. pratensis and seven populations of octoploid ssp. paludosa). Earlier studies have shown that attack rates by the main herbivore, the orange tip butterfly Anthocharis cardamines, are lower in populations of octoploids than in populations of tetraploids, and vary among populations. In the common garden
experiment, a combination of natural and artificial damage significantly reduced seed and flower production. We measured tolerance
based on four plant-performance metrics: survival, growth, seed production and clonal reproduction. For three of these measurements,
tolerance of damage did not differ between ploidy levels. For clonal reproduction, the octoploids had a higher tolerance than
the tetraploids, although they experience lower herbivore attack rates in natural populations. Populations from sites with
high levels of herbivory had higher tolerance, measured by seed production, than populations with low levels of herbivory.
We did not detect any significant costs of tolerance. We conclude that high intensity of herbivory has selected for high tolerance
measured by seed production in C. pratensis. 相似文献
842.
Leena Taji Doneal Thomas Matthew J. Oliver Jane Ip Yiwen Tang Angie Yeung Rebecca Cooper Andrew A. House Phil McFarlane Peter G. Blake 《CMAJ》2021,193(8):E278
BACKGROUND:Patients undergoing long-term dialysis may be at higher risk of infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and of associated disease and mortality. We aimed to describe the incidence, risk factors and outcomes for infection in these patients in Ontario, Canada.METHODS:We used linked data sets to compare disease characteristics and mortality between patients receiving long-term dialysis in Ontario who were diagnosed SARS-CoV-2 positive and those who did not acquire SARS-CoV-2 infection, between Mar. 12 and Aug. 20, 2020. We collected data on SARS-CoV-2 infection prospectively. We evaluated risk factors for infection and death using multivariable logistic regression analyses.RESULTS:During the study period, 187 (1.5%) of 12 501 patients undergoing dialysis were diagnosed with SARS-CoV-2 infection. Of those with SARS-CoV-2 infection, 117 (62.6%) were admitted to hospital and the case fatality rate was 28.3%. Significant predictors of infection included in-centre hemodialysis versus home dialysis (odds ratio [OR] 2.54, 95% confidence interval [CI] 1.59–4.05), living in a long-term care residence (OR 7.67, 95% CI 5.30–11.11), living in the Greater Toronto Area (OR 3.27, 95% CI 2.21–4.80), Black ethnicity (OR 3.05, 95% CI 1.95–4.77), Indian subcontinent ethnicity (OR 1.70, 95% CI 1.02–2.81), other non-White ethnicities (OR 2.03, 95% CI 1.38–2.97) and lower income quintiles (OR 1.82, 95% CI 1.15–2.89).INTERPRETATION:Patients undergoing long-term dialysis are at increased risk of SARS-CoV-2 infection and death from coronavirus disease 2019. Special attention should be paid to addressing risk factors for infection, and these patients should be prioritized for vaccination.As of Aug. 20, 2020, in Ontario, Canada’s most populous province, almost 41 000 people had tested positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes coronavirus disease 2019 (COVID-19),1 which represented 0.3% of the provincial population. Close to 2800 people had died, a case fatality rate of 6.8%.2Patients undergoing dialysis have high rates of comorbid conditions, are often older adults, have varying degrees of immunosuppression and are more likely to reside in long-term care, which puts them at risk of both acquiring SARS-CoV-2 and developing complicated disease.3,4 Furthermore, in Ontario, those who receive in-centre hemodialysis typically have 3 treatments per week in outpatient units located in or affiliated with hospitals, and the consequent inability to fully self-isolate means that patients undergoing hemodialysis likely have an even higher risk of SARS-CoV-2 infection.3,4 Recent studies support this but do not compare infection rates with those in the local population of patients not undergoing dialysis.5–10 Several studies have reported SARS-CoV-2 infection in single or multicentre cohorts of patients undergoing dialysis,5–10 but we are unaware of any that have identified risk factors for infection at the level of a large region. Some studies have found that patients with SARS-CoV-2 infection who are undergoing dialysis are at high risk of severe illness and death.6–10 相似文献
843.
844.
Rafiqul Hyder Taina Pennanen Leena Hamberg Eeva J. Vainio Tuula Piri Jarkko Hantula 《Fungal Ecology》2013,6(5):387-396
We investigated the effects of two recently described dsRNA mycoviruses, HetRV3-ec1 and HetRV6-ab6, on Heterobasidion wood decay fungi. The viruses originally inhabited Heterobasidion ecrustosum and Heterobasidion abietinum, and were transferred in the laboratory into other Heterobasidion species. Isogenic virus-free and virus-infected Heterobasidion isolates were used to test the effects of these viruses on their hosts' growth rate and competitive ability against mycorrhizal and decay fungi (Paxillus involutus, Meliniomyces bicolor and Phlebiopsis gigantea). This study shows that: (i) a single virus strain confers different effects on different Heterobasidion host strains; and (ii) a single virus strain may have contrasting effects on the fitness of a single host isolate (ranging from no effect to harmful or beneficial) depending on environmental and ecological conditions. We also report for the first time on the antagonism of Helotiales belonging to the sub-group Rhizocyphus–Meliniomyces against Heterobasidion species. 相似文献
845.
We studied the matrilinear genetic structure of the Siberian tit Parus cinctus by sequencing 911 bp of the mitochondrial control region of 56 birds from Fennoscandia and 3 from Yakutia, central Siberia, representing subspecies P. c. lapponicus and P. c. cinctus , respectively. One major haplotype comprised 35.7% of all birds and was present in all Fennoscandian populations. Sequence variation of 5 museum specimens from Norway fitted with the pattern of the present-day birds. The nucleotide diversity was 0.00205±0.00025 in the Fennoscandian population and no population structuring was detected. The star-like phylogeny suggests a recent expansion of the population size in the evolutionary time scale. A modern decline of the population size from 200 000 pairs to 50 000 pairs in Finland has resulted from cutting and fragmentation of old-growth forests, but the effects of this could not yet be detected in the mtDNA pattern. However, the nucleotide diversity differed among populations being the highest at Kuusamo, close to the Russian border. Conceivably, the gene flow maintained by the substantial migration of Siberian tits is sufficient to prevent differentiation of local populations in Fennoscandia. Presumably the large conservation areas in NE Finland and on the Russian side of the border contribute to the high genetic variation observed in the Kuusamo population. Comparison of the mtDNA phylogeny of the Siberian tit with the phylogenies of the great tit, the blue tit and the willow tit showed that the Siberian tit and some other non-migratory species of the foliage gleaning guild share similar post glacial histories in the western palaearctic. 相似文献
846.
Summary The Fennoscandian mountain birchwoods and the ecologically and physiognomically closely related oceanic coastal birchwoods are found in all the boreal zones (northern boreal, middle boreal, southern boreal and hemiboreal) in Europe. In general, they are characteristic and commonly dominant (not necessarily in pure stands) in the oceanic to suboceanic, cool and windy western sections of the boreal zones.The same pattern is clearly repeated on the east coast of Eurasia, despite of its less pronounced oceanity. There the most oceanic boreal sections are dominated by forests of Betula ermanii s. lat. (ranging from the northern boreal to the hemiboreal zone) and Alnus maximowiczii (essentially middle and northern boreal).The western North American Alnus sinuata woods may be interpreted as homologous to the Fennoscandian birchwoods. They are found mainly in the middle and northern (upper) boreal zones in southern Alaska (also in the mountains of British Columbia and SW Yukon). In southern Alaska there are also some fragments of oceanic birchwoods.In eastern North America such homologous deciduous forests are poorly developed.Among the true inland mountain birchwoods only those of the northern Ural Mts., some Transbaikalian mountains, the Himalaya and (with reservation) the Caucasus are referred to the distinct homologies of the Fennoscandian birchwoods.The widespread timber-line alder scrubs consisting of Alnus crispa and related taxa in North America and Eurasia are not included in such homologies.The occurrence of treeless boreal maritime heaths and grasslands is closely related to the distribution of birch and alder forests. The lowlands of Iceland, the Aleutian Islands and the Kuril Islands, for instance, are referred to the boreal heath sections rather than to the arctic.
Zusammenfassung Die fennoskandischen Gebirgsbirkenwälder und die ökologisch und physiognomisch nahe verwandten ozeanischen Küstenbirken-wälder kommen in allen borealen Zonen vor. Sie sind typisch und allgemein dominant (nicht immer in reinen Beständen) in den ozeanisch-subozeanischen, kühlen und windigen Sektionen der borealen Zonen.Dasselbe Phänomen wiederholt sich deutlich auch an der Ostküste Eurasiens, ungeachtet ihrer geringeren Ozeanität. In den meist ozeanischen borealen Sektionen herrschen die Wälder von Betula ermanii s. lat. (von der nordborealen zur hemiborealen Zone) und von Alnus maximowiczii (eigentlich mittel- und nordboreal).Im westlichen Nordamerikakönnen die Alnus sinuata-Wälder als homolog mit den fennoskandischen Birkenwäldern erklärt werden. Sie kommen hauptsächlich in den mittel- und nordborealen Zonen in Südalaska vor (auch in den Gebirgen von Britisch-Kolumbien und im südwestlichen Yukon). Auch in Südalaska gibt es einige Fragmente von ozeanischen Birkenwäldern.Die homologen Laubwälder im östlichen Nordamerika sind schwach entwickelt.Nur die Binnengebirgsbirkenwälder, die in Nordural, in Trans-baikalien, im Himalaya und (unter Vorbehalt) in Kaukasien vorkommen, werden für homolog mit den fennoskandischen Birkenwäldern angesehen.Die an der Waldgrenze weitverbreiteten Erlengebüsche (Alnus crispa und nahe verwandt) in Nordamerika und Eurasien werden nicht in solche Homologien aufgenommen.Das Vorkommen der baumlosen borealen maritimen Heiden und Wiesen ist sehr nahe verwandt mit den Birken und Erlenwäldern. Zum Beispiel die Tiefländer von Island, Aleuten und Kurilen werden besser zu den borealen Heide-Sektionen als zur arktischen Zone gezählt.相似文献
847.
Kulha Niko Pasanen Leena Holmström Lasse De Grandpré Louis Kuuluvainen Timo Aakala Tuomas 《Ecosystems》2019,22(4):709-724
Ecosystems - Identifying the scales of variation in forest structures and the underlying processes are fundamental for understanding forest dynamics. Here, we studied these scale-dependencies in... 相似文献
848.
Jacqueline M. Vink August B. Smit Patrick Sullivan Jouke-Jan Hottenga Witte J. Hoogendijk Leena Peltonen Jaakko Kaprio Nancy L. Pedersen Tim D. Spector Katherine I. Morley Andrew C. Heath Rudi G.J. Westendorp Henning Tiemeier Andre G. Uitterlinden Najaf Amin Brenda W. Penninx Dorret I. Boomsma 《American journal of human genetics》2009,84(3):367-379
849.
Genetic isolates are highly useful in analyses of the molecular background of complex diseases since the enrichment of a limited number of predisposing genes can be predicted in representative families or in specific geographical regions. It has been suggested that the pathophysiology and etiology of familial hemiplegic migraine (FHM) and typical migraine with aura are most probably the same. Recent assignment of FHM locus to chromosome 19p in two French families makes it now possible to test this hypothesis. We report here linkage data on four families with multiple cases of migraine disorder originating from the genetically isolated population of Finland. We were interested to discover whether the migraine in these families would also show linkage to the markers on 19p. We could exclude a region of 50 cM, flanking the reported FHM locus, as a site of migraine locus in our four families. It seems evident that locus heterogeneity exists between different diagnostic classes of migraine spectrum of diseases and also between different ethnic groups. 相似文献
850.
Laura Huilaja Tiina Hurskainen Helena Autio-Harmainen Silke C Hofmann Raija Sormunen Juha R?s?nen Mika Ilves Claus-Werner Franzke Leena Bruckner-Tuderman Kaisa Tasanen 《Matrix biology》2008,27(3):190-200
In pemphigoid gestationis (PG), autoantibodies target collagen XVII, a hemidesmosomal transmembrane protein, which is an important element in cutaneous epithelial adhesion and signalling. We report that collagen XVII is expressed in the first trimester and term syncytial and cytotrophoblastic cells of normal placenta and in epithelial cells of amniotic membrane. Immunoelectron microscopy confirmed the localization of collagen XVII to the hemidesmosomes of amniotic epithelium. Examination of three PG placentas showed mild villitis, but there were no differences between collagen XVII expression levels or immunostaining signals as compared to normal placenta. Collagen XVII expression was also detected in cultured extravillous trophoblast HTR-8/SVneo cells, where collagen XVII expression was upregulated by PMA and TGF-beta1. Interestingly, the presence of Col15, the cell migration domain of collagen XVII, induced the migration of HTR-8/SVneo cells in transmigration assay. Analysis of amniotic fluid samples at different gestational weeks revealed that a large quantity of collagen XVII ectodomain was shed into amniotic fluid throughout pregnancy. Biochemical and immunoblotting analysis indicated that the ectodomain in amniotic fluid is structurally very similar to the ectodomain produced by cultured keratinocytes. Cultured cells from amniotic fluid samples also expressed collagen XVII. Our results suggest that collagen XVII may contribute to the invasion of extravillous trophoblasts during placental development and is also required for the integrity of amniotic basement membrane. Although the exact pathomechanism of PG is still largely unknown, the clinical symptoms of PG are initiated after the expression of collagen XVII in placenta during the first trimester of pregnancy. 相似文献