Forming of the Pavlov pouch changes functional condition of the adherent mucosal layer in upper regions of the digestive tract

In result of forming the Pavlov small gaster, secretion of pepsine in isolated part and, probable, in other parts of the gaster, was increased. This entailed a decrease in the pepsin sorption level on the luminal surface of adherent mucous layer of the gaster parts and intestine under study. This led to a drop of the level of structure glycoproteins and to increase in the per cent contents of polymeric glycoproteins in the whole pool of the mucous layer glycoproteins. The data obtained suggest that forming of the Pavlov small gaster indices significant changes of the adherent mucous layer structure-functional condition both in the gaster and in lower parts of the intestine.     

Development of protective functions of the pig digestive tract in ontogenesis

It has been found that the state of protective functions of the digestive tract change during postnatal period. The biosynthesis and secretion of glycoproteins of mucus layer which is the main protective structure of digestive tract depend on the hormonal background and the nutrition conditions. The biosynthesis stages and secretion glycoproteins result in sexual maturity and in conditions of definitive nutrition. Opposite to that, the antiradical activity of adherent mucous layer decreases with age. The allocation of the studied components of adherent mucous layer in the stomach and in the intestine is determined.     

Environment of planktic crustaceans as changed by hornwort: Effect on abundance of Daphnia

The effect of submersed hydrophyte Ceratophyllum demersum L. on the abundance of Daphnia longispina O.F. Müller has been studied. The experiments demonstrated that the hydrochemical characteristics in overgrowths of Ceratophyllum are within the limits of tolerance for D. longispina. The concentrations of waterborne phosphates, chlorophyll a, and bacterial biomass increase in the presence of hornwort. In plant overgrowths, Daphnia is suppressed due to the restriction of its movement. In a medium containing only metabolites of Ceratophyllum, the abundance of Daphnia longispina increases due to the enrichment of food resources.     

Structure-functional analysis of interactions of terminal deoxynucleotidyl transferase with new non-nucleoside substrates

New non-nucleoside esters of phosphoric acid containing various hydrophobic groups, namely (1) N-(2-tripticencarbonyl)-4-aminobutyl; (2) 5-phenylsubstituted N-(2,4-dinitrophenyl)-4-aminobutyl; (3) N-(4-phenylbenzoyl)- and N-(4-(N-benzylamino)benzoyl)-2-aminoethyl groups, as well as (4) diphenylmethyl and fluorenyl groups were synthesized and studied as substrates of terminal deoxynucleotidyl transferase. With the exception of the two latter derivatives, all the analogues displayed substrate properties and could incorporate into the deoxyoligonucleotide 3′-end. As it was shown in biochemical experiments and by computer modeling, a linker joining the triphosphate and hydrophobic fragments of the molecule was necessary for these compounds to display substrate properties.