全文获取类型
收费全文 | 318篇 |
免费 | 19篇 |
专业分类
337篇 |
出版年
2022年 | 2篇 |
2021年 | 5篇 |
2020年 | 2篇 |
2018年 | 6篇 |
2017年 | 4篇 |
2016年 | 7篇 |
2015年 | 10篇 |
2014年 | 13篇 |
2013年 | 10篇 |
2012年 | 18篇 |
2011年 | 18篇 |
2010年 | 17篇 |
2009年 | 7篇 |
2008年 | 16篇 |
2007年 | 17篇 |
2006年 | 18篇 |
2005年 | 21篇 |
2004年 | 19篇 |
2003年 | 19篇 |
2002年 | 15篇 |
2001年 | 8篇 |
2000年 | 9篇 |
1999年 | 11篇 |
1998年 | 6篇 |
1997年 | 3篇 |
1996年 | 2篇 |
1995年 | 2篇 |
1994年 | 6篇 |
1993年 | 1篇 |
1992年 | 4篇 |
1991年 | 2篇 |
1990年 | 1篇 |
1989年 | 3篇 |
1988年 | 6篇 |
1987年 | 3篇 |
1986年 | 6篇 |
1985年 | 4篇 |
1984年 | 1篇 |
1983年 | 3篇 |
1982年 | 3篇 |
1981年 | 2篇 |
1980年 | 2篇 |
1974年 | 1篇 |
1973年 | 1篇 |
1972年 | 1篇 |
1963年 | 1篇 |
1949年 | 1篇 |
排序方式: 共有337条查询结果,搜索用时 6 毫秒
331.
A number of 2-phthalimidoethanesulphonamides, new derivatives of the inhibitory neuromodulator taurine, were tested for their anticonvulsant activity in maximal electroshock seizure and pentetrazole seizure threshold tests in mice. Certain lower N-alkylamides showed activity, methylamide, dimethylamide and isopropylamide derivatives and the unsubstituted amide being pharmacologically most promising. Possible interferences with the intracellular uptake, release and membrane binding of taurine and GABA were assessed in an attempt to elucidate their mode of action. Since the uptake and release processes were only minimally affected, but the sodium-independent binding of GABA and/or taurine to synaptic membranes strongly reduced, the compounds studied may preferentially act as taurine or GABA receptor agonists. 相似文献
332.
333.
Priit Tammeorg Asko Simojoki Pirjo Mäkelä Frederick L. Stoddard Laura Alakukku Juha Helenius 《Plant and Soil》2014,379(1-2):389-390
334.
Pirjo Karunen 《Phytochemistry》1974,13(10):2209-2213
Polytrichum commune Hedw. spores were found to contain the polyunsaturated hydrocarbons normal all-cis-6,9,12,15-heneicosatetrane (20· ± 0·5 μg/100 mg spores) and normal all-cis-3,6,9,12,15-heneicosapentaene (22·5 ± 1·2 μg/100 mg spores), N- alkanes were present only in minor amounts. 相似文献
335.
Molecular lineage diversity and inter‐oceanic biogeographical history in Hiatella (Mollusca,Bivalvia) 下载免费PDF全文
Hiatella is one of the most widespread marine bivalve genera, occurring in diverse habitats from the temperate to polar latitudes in both hemispheres, and in fossil strata since almost 150 Myr ago. Despite variation in some biological and morphological traits, characters to resolve the current systematic structure consistently across the range of the genus are not known: all samples are often referred to a single species, Hiatella arctica (L.). Exploring the systematics of Hiatella using partial sequences of three genes (mitochondrial COI, and the nuclear ANT and 28S rRNA), we find high diversity of deep lineages (11–22% p‐distance in COI), and identify at least 13 distinct taxa both by heuristic criteria (congruence of the nuclear and mtDNA data) and by coalescence‐based analyses. At several localities, two or three of these cryptic species were found in sympatry. In the framework of previous fossil evidence and of hypotheses of paleoceanographical connections, scenarios of the phylogeny and biogeographical history of the identified species at a range of different time scales are outlined. The distinction between the main North Pacific and North Atlantic Hiatella clades and systematic diversification within each of them seem to have followed a Miocene trans‐Panamanian invasion. Apart from such earlier intra‐basin diversification, the data suggest that three successive counter‐invasions from the Pacific to the Atlantic via the Arctic Ocean route have later contributed to the current North Atlantic Hiatella diversity. These invasions probably took place in connection with (i) the Great Trans‐Arctic Biotic Interchange in the Pliocene, (ii) the last interglacial period c. 120 kya and (iii) the Holocene, postdating the last glaciation. This sequence of trans‐Arctic invasions is largely analogous to that hypothesized for some other boreal‐arctic bivalves. 相似文献
336.
The bifunctional long-chain acids in extracts and alkaline hydrolysates of extractive-free tissues from the green and senescent parts of Sphagnum fuscum were investigated by GC and GC/MS. A series of C14– C26hydroxy acids was liberated by alkaline hydrolysis of senescent tissue demonstrating the presence of insoluble polymeric lipid esters in the moss. In the corresponding hydrolysates of the topmost green parts of the shoot the amounts of these acids were significantly smaller. It is suggested that the presence of such polymeric esters in S. fuscum contributes to the cell-wall resistance of this peat-forming moss. 相似文献
337.
The uptake ofl-carnitine was characterized in mouse brain synaptosomal preparations, with an emphasis on mutual interactions with GABA uptake systems. The uptake consisted of nonsaturable diffusion and one saturable energy- and sodium-dependent component. GABA,l-DABA and nipecotate were strong and hypotaurine and homotaurine moderate inhibitors of the uptake. The inhibition by GABA was shown to be competitive. GABA uptake contained two saturable transport components, high- and low-affinity. It was most strongly inhibited by nipecotate andl-DABA, but also by carnitine and hypotaurine. The high-affinity uptake of GABA was competitively inhibited by carnitine, but the inhibition of the low-affinity uptake of GABA was of the mixed type. The results suggest that GABA and carnitine share the same carrier system at synaptosomal membranes. However, GABA is the preferred substrate and the carnitine concentrations which significantly inhibited GABA uptake exceed the physiological carnitine levels in vivo. 相似文献