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51.
In vitro plants of Musa acuminata (AAA) “Cavendish” challenged with the non-pathogenic yeast strain Sporobolomyces salmonicolor resulted in the induction of a large number of metabolites. These included phenylphenalenone-type compounds, of which nine have been identified. Two of these are new phenylnaphthalic anhydrides, 2-(4′-β-glucosyloxyphenyl)-1,8-naphthalic anhydride and 2-(3′,4′-dihydroxyphenyl)-1,8-naphthalic anhydride. The chemical structures of these compounds were identified using nuclear magnetic resonance (NMR) spectroscopic and mass spectrometric (MS) techniques. 相似文献
52.
Lilian Noindorf Ana C Bonatto Rose A Monteiro Emanuel M Souza Liu U Rigo Fabio O Pedrosa Maria BR Steffens Leda S Chubatsu 《BMC microbiology》2011,11(1):8
Background
The PII protein family comprises homotrimeric proteins which act as transducers of the cellular nitrogen and carbon status in prokaryotes and plants. In Herbaspirillum seropedicae, two PII-like proteins (GlnB and GlnK), encoded by the genes glnB and glnK, were identified. The glnB gene is monocistronic and its expression is constitutive, while glnK is located in the nlmAglnKamtB operon and is expressed under nitrogen-limiting conditions. 相似文献53.
Khatau SB Kusuma S Hanjaya-Putra D Mali P Cheng L Lee JS Gerecht S Wirtz D 《PloS one》2012,7(5):e36689
The actin filament cytoskeleton mediates cell motility and adhesion in somatic cells. However, whether the function and organization of the actin network are fundamentally different in pluripotent stem cells is unknown. Here we show that while conventional actin stress fibers at the basal surface of cells are present before and after onset of differentiation of mouse (mESCs) and human embryonic stem cells (hESCs), actin stress fibers of the actin cap, which wrap around the nucleus, are completely absent from undifferentiated mESCs and hESCs and their formation strongly correlates with differentiation. Similarly, the perinuclear actin cap is absent from human induced pluripotent stem cells (hiPSCs), while it is organized in the parental lung fibroblasts from which these hiPSCs are derived and in a wide range of human somatic cells, including lung, embryonic, and foreskin fibroblasts and endothelial cells. During differentiation, the formation of the actin cap follows the expression and proper localization of nuclear lamin A/C and associated linkers of nucleus and cytoskeleton (LINC) complexes at the nuclear envelope, which physically couple the actin cap to the apical surface of the nucleus. The differentiation of hESCs is accompanied by the progressive formation of a perinuclear actin cap while induced pluripotency is accompanied by the specific elimination of the actin cap, and that, through lamin A/C and LINC complexes, this actin cap is involved in progressively shaping the nucleus of hESCs undergoing differentiation. While, the localization of lamin A/C at the nuclear envelope is required for perinuclear actin cap formation, it is not sufficient to control nuclear shape. 相似文献
54.
Selfish DNA poses a significant challenge to genome stability and organismal fitness in diverse eukaryotic lineages. Although selfish mitochondrial DNA (mtDNA) has known associations with cytoplasmic male sterility in numerous gynodioecious plant species and is manifested as petite mutants in experimental yeast lab populations, examples of selfish mtDNA in animals are less common. We analyzed the inheritance and evolution of mitochondrial DNA bearing large heteroplasmic deletions including nad5 gene sequences (nad5Δ mtDNA), in the nematode Caenorhabditis briggsae. The deletion is widespread in C. briggsae natural populations and is associated with deleterious organismal effects. We studied the inheritance patterns of nad5Δ mtDNA using eight sets of C. briggsae mutation-accumulation (MA) lines, each initiated from a different natural strain progenitor and bottlenecked as single hermaphrodites across generations. We observed a consistent and strong drive toward higher levels of deletion-bearing molecules in the heteroplasmic pool of mtDNA after ten generations of bottlenecking. Our results demonstrate a uniform transmission bias whereby nad5Δ mtDNA accumulates to higher levels relative to intact mtDNA in multiple genetically diverse natural strains of C. briggsae. We calculated an average 1% per-generation transmission bias for deletion-bearing mtDNA relative to intact genomes. Our study, coupled with known deleterious phenotypes associated with high deletion levels, shows that nad5Δ mtDNA are selfish genetic elements that have evolved in natural populations of C. briggsae, offering a powerful new system to study selfish mtDNA dynamics in metazoans. 相似文献
55.
Background
Cancer of the oral tongue is the second most common cancer among males in various parts of India. Despite advances in diagnosis and treatment the failure rates in cancer of the oral tongue are high and survival poor. Majority of these failures occur in untreated neck. 相似文献56.
The present paper reports the distribution of finger ridge count correlations among four tribal populations from Andhra Pradesh, India viz., Dulia, Kotia, Manne Dora and Manzai Mali, and examines the intra and inter population variation. Higher correlations are recorded in left hands compared to right hands, but they are not significant. The homologous fingers exhibit a stronger correlation. In all the tribes, the correlations between right hand fingers are relatively higher among women when compared to men. Regarding inter population variation Dulia men differ significantly from the men of Manne Dora and the Manzai Mali tribes, and Kotia women also differ from the women of the Manne Dora significantly. The average correlation coefficient of the present populations is similar to other Indian populations reported earlier but lower than African and European populations. 相似文献
57.
Summary A total of 118 cases of microcephaly were clinically evaluated under two main groups: primary microcephaly (61 cases) and
secondary microcephaly (57 cases). Secondary cases were generally characterized by convulsions, spasticity, and other congenital
anomalies. Estimates of segregation frequency obtained separately in primary and secondary cases indicated that the primary
consanguineous cases were most probably due to a single recessive gene. The segregation frequency was substantially less in
other types, indicating much lower genetic risks in these cases. 相似文献
58.
The asymmetry among the four tribal populations Dulia, Kotia, Manne Dora and Manzai Mali is reported. The mean directional asymmetry (MDA) and mean absolute asymmetry (MAA) were measured for homologous fingers. The asymmetry follows a decreasing trend in radio-ulnar direction with higher mean values in thumb and index finger. The individual variation is also higher in these fingers. Neither sexual nor population differences are consistent. Jantz's Square root of A2 (another measure to assess asymmetry) for total finger ridge count and absolute finger ridge count does not indicate any significant sexual or ethnic differences. The results suggest that the underlying mechanisms influencing the level of asymmetry may be similar for all groups, and that certain dermatoglyphic areas like the thumb are more vulnerable to developmental/environmental stress, that cause asymmetry at the developmental stage. 相似文献
59.
澳洲塔斯马尼亚霍巴特冬季驯化黄翅澳蜜鸟的代谢率 总被引:2,自引:2,他引:0
L. P. E. Kusuma YUNI R.W. ROSE 《动物学报》2005,51(2):338-343
在5-40°C温度范围内, 测定了澳大利亚塔斯马尼亚黄翅澳蜜鸟(Phylidonyris novaehollandiae) (平均体重24 .1 ±0. 27 g) 冬季的耗氧量。结果表明, 热中性区是25-35°C。基础代谢率是4. 92 ±0 .14 ml/g. h,分别比Lasiewski and Dawson (1967) 和Aschoff and Pohl (1970) 基于体重的关于雀型鸟类的期望值高57%和77%。本研究结果同样也比已经报道的分布在澳洲大陆的该物种的代谢率高。 相似文献
60.