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Kperkouma Wala Agbélessessi Y. Woegan Wiyao Borozi Marra Dourma Abalo Atato Komlan Batawila Koffi Akpagana 《African Journal of Ecology》2012,50(3):355-366
Protected areas constitute strategy for biodiversity conservation. Unfortunately, these sanctuaries of biodiversity are submitted to a high human pressure in Togo. This study carried out in the Alédjo protected area, aimed to make an analysis of various forms of human footprints and their impact on its plant resources. Methodological approach was based on forest inventory completed by inquiries. Ninety‐four wooded species belonging to 35 families were counted. Floristic data analysis showed that seven species: Isoberlinia doka Craib & Stapf, Daniellia oliveri (Rolfe) Hutch. & Dalz., Berlinia grandiflora (Vahl) Hutch. & Dalz., Pterocarpus erinaceus Poir., Zanha golungensis Hiern, Khaya senegalensis (Desv.) A. Juss., Pentadesma butyracea Sabine was prominent. Five vegetation types were identified: riparian forests, dry forests, open forests, savanna woodlands, tree/shrub savannas with variable structural characteristics. The diversity indices in these plant communities are well significant and indicate a good distribution of species in the area. Several human activities such as fuel wood, fruits and medicinal plants gathering, carbonization, pasture were found within the protected area. Local authorities and associations are involved in the management of the protected area, but the participation of local populations needs to be improved. 相似文献
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Jamonneau V Ilboudo H Kaboré J Kaba D Koffi M Solano P Garcia A Courtin D Laveissière C Lingue K Büscher P Bucheton B 《PLoS neglected tropical diseases》2012,6(6):e1691
The final outcome of infection by Trypanosoma brucei gambiense, the main agent of sleeping sickness, has always been considered as invariably fatal. While scarce and old reports have mentioned cases of self-cure in untreated patients, these studies suffered from the lack of accurate diagnostic tools available at that time. Here, using the most specific and sensitive tools available to date, we report on a long-term follow-up (15 years) of a cohort of 50 human African trypanosomiasis (HAT) patients from the Ivory Coast among whom 11 refused treatment after their initial diagnosis. In 10 out of 11 subjects who continued to refuse treatment despite repeated visits, parasite clearance was observed using both microscopy and polymerase chain reaction (PCR). Most of these subjects (7/10) also displayed decreasing serological responses, becoming progressively negative to trypanosome variable antigens (LiTat 1.3, 1.5 and 1.6). Hence, in addition to the "classic" lethal outcome of HAT, we show that alternative natural progressions of HAT may occur: progression to an apparently aparasitaemic and asymptomatic infection associated with strong long-lasting serological responses and progression to an apparently spontaneous resolution of infection (with negative results in parasitological tests and PCR) associated with a progressive drop in antibody titres as observed in treated cases. While this study does not precisely estimate the frequency of the alternative courses for this infection, it is noteworthy that in the field national control programs encounter a significant proportion of subjects displaying positive serologic test results but negative results in parasitological testing. These findings demonstrate that a number of these subjects display such infection courses. From our point of view, recognising that trypanotolerance exists in humans, as is now widely accepted for animals, is a major step forward for future research in the field of HAT. 相似文献
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R. Kambiré K. Lingué F. Courtin I. Sidibé D. Kiendrébéogo K.E. N’gouan L. blé D. Kaba M. Koffi P. Solano B. Bucheton V. Jamonneau 《Parasite (Paris, France)》2012,19(4):389-396
The objective of this paper was to describe recent data from Burkina Faso and Côte d’Ivoire on Human African Trypanosomosis medical monitoring in order to (i) update the disease situation in these two countries that have been sharing important migratory, economic and epidemiological links for more than a century and (ii) to define the future strategic plans to achieve the goal of a sustainable control/elimination process. Results of active and passive surveillance indicate that all sleeping sickness patients diagnosed these last years in Burkina Faso were imported cases from Côte d’Ivoire. Nevertheless the re-introduction of the parasite is effective and the risk of a resumption of transmission exists. In Côte d’Ivoire, few cases are still diagnosed in several historical foci and the fear exists that the disease could reemerge in these foci or spread to other areas. In order to achieve a sustainable elimination of sleeping sickness in these two countries, control entities have to adapt their strategy to the different epidemiological contexts. At the exception of specific cases, the current disease prevalence no longer justifies the use of expensive medical surveys by exhaustive screening of the population. New disease control strategies, based on the exchange of epidemiological information between the two countries and integrated to the regular national health systems are required to target priority intervention areas. Follow-up in time of both treated patients and serological suspects that are potential asymptomatic carriers of parasite is also important. In parallel, researchers need to better characterize the respective roles of the human and animal reservoir in the maintenance of transmission and evaluate the different control strategies taken by National Control Programs in term of cost/effectiveness to help optimize them. 相似文献
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The aim of this work is to specify the relationship between the thyroid function and the hypothalamo-hypophyso-gonadal axis. Qualitative and quantitative repercussions of a thyroid pathology on human or animal fertility, male or female are very variable. A review of mechanisms of action is presented, illustrating: the complexity of the phenomena in cause; the necessity not to dissociate thyroid and reproductive function either clinically or biologically; the serious consequences of either undetected or untreated neo-natal thyroid pathology. 相似文献
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Holzmuller P Biron DG Courtois P Koffi M Bras-Gonçalves R Daulouède S Solano P Cuny G Vincendeau P Jamonneau V 《Microbes and infection / Institut Pasteur》2008,10(1):79-86
Human African trypanosomiasis is characterised by an important clinical diversity. Although Trypanosoma brucei gambiense field stocks isolated from patients in the same focus did not exhibit apparent genetic variability, they showed marked differences in terms of virulence (capacity to multiply inside a host) and pathogenicity (ability of producing mortality) in experimental murine infections. Two strains exhibiting opposite pathogenic and virulence properties in mouse were further investigated through their host-parasite interactions. In vitro, parasite bloodstream forms or soluble factors (or secretome) from both strains induced macrophage arginase as a function of their virulence. Arginase expression, a hallmark of macrophage alternative activation pathway, favours trypanosome bloodstream forms development. Moreover, a comparative proteomic study of the trypanosome stocks' secretomes evidenced both a differential expression of common molecules and the existence of stock specific molecules. This highlighted the potential involvement of the differential expression of the same genome in the diverse infectious properties of trypanosomes. 相似文献
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A. Kouamé-Koutouan N. Aboukoua-Kouassi D. Koffi M. Méité I. Sanogo J.-M. Séry 《Médecine Nucléaire》2009,33(10):604-608
Osteonecrosis is the most frequent complications of sickle-cell disease (SCD) whose prevalence in Côte d’Ivoire is 21%. The main of this study was to compare scintigraphy, clinical and radiological observations to assess earlier diagnosis in SCD osteonecrosis. It was a prospective study about 45 SCD patients who presented coxopathy and had radio-labelled diphosphonates bone scintigraphy. The results revealed 49% of lesions whose 48% appeared wiyh homogeneous hyperfixation, 11% homogeneous hypofixation, 5% of hypofixation contourned by hyperfixation. Eighty-one percent of lesions concerned femoral head, 6% femoral condyle and 3% humoral head. Fifty percent of osteonecrosis was not visible in radiology and corresponded to the earlier stade. These invisible radiology aspects were observed in 100% hips without lameness, and in 43% permanent lameness. Scintigraphy (sensitive in 100%) isolated 38% more than conventional radiography. In main to improve SCD osteonecrosis prognostic in Côte d’Ivoire, this preliminary study outline that scintigraphy is fundamental in management. 相似文献
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Boguinard S. H. B. Guiraud Olivier Fouet Caudou I. Trebissou Désiré Pokou Ronan Rivallan Xavier Argout Kouamé K. Koffi Boaké Koné Bi I. A. Zoro Claire Lanaud 《Tree Genetics & Genomes》2018,14(4):52
Resistance to Cocoa Swollen Shoot Virus disease (CSSVD) is becoming an increasingly important criterion for selection of new cocoa cultivars in Côte-d’Ivoire, where the disease resurfaced since 2003. This virus can seriously affect the yield of trees with a loss of 25%, 1 year after infection, to around 100% 3 years after. In order to find tolerant plant material, 337 farm accessions have been collected on fields affected by CSSVD, according to the status of accessions potentially tolerant (APT) or susceptible (APS). Both phenotypic groups were genotyped using 30 microsatellite markers (SSR) in the presence of representative clones of the ten genetic groups of cocoa. This study revealed 214 alleles with the set of primer pairs used. The number of alleles per locus was between 3 and 16 with an average of 7.13 alleles per locus. The results showed a high contribution of genetic diversity within population (Hs?=?0.51) to the total genetic diversity (Ht?=?0.53) for the two studied groups. There was no significant difference between tolerant and susceptible groups (Fst?=?0.05). These results suggest that APT could be a potential genetic reservoir for other traits of interest associated with virus resistance. The phylogenetic tree, as the STRUCTURE analysis of Ivorian cocoa population, showed a distribution of individuals following four groups marked by a high contribution of group 4 (Nanay, Maranon, Guiana) followed by group 2 (Criollo), and group 1 (Amelonado), and a lower contribution of group 3 (Iquitos, Purus, Nacional, Curaray, Contamana). 相似文献
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Tchin Darré Bayaki Saka Abas Mouhari-Toure Mazamaesso Tchaou Améyo Monique Dorkenoo Kwamé Doh Atchi Walla Koffi Amégbor Vincent Palokinam Pitché Gado Napo-Koura 《Mycopathologia》2018,183(6):961-965