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21.
Robert J. Knell 《Evolution; international journal of organic evolution》1999,53(3):957-961
Few studies have investigated the consequences of parasite-mediated sexual selection on the parasites involved. In some cases parasite-mediated sexual selection could lead to increased virulence, but I develop a simple model that shows that, if a parasite is sexually transmitted (i.e., is a sexually transmitted disease, or STD) and if mating success of the host is adversely affected by the parasite, then less virulent STDs will be selected for because transmission of the STD depends on the mating success of the host. This selection for reduced virulence could have important consequences for the role of STDs in sexual selection. 相似文献
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23.
Effect of MDMP on protein synthesis in wheat and bacteria 总被引:4,自引:0,他引:4
24.
R. J. Knell 《Journal of Zoology》2009,278(2):83-90
In some cases male animals engage in aggressive contests for access to females, in others they adopt more passive strategies and invest in traits that assist them in detecting females or in competing with rivals in other ways, such as sperm competition. One possible factor determining the fitness of these different strategies is population density. Theoretically, aggressive tactics should be found at intermediate population densities. At low densities males that invest in traits related to searching for mates could be favoured, whereas at the highest densities males that fight over females might pay excessive costs for this behaviour because of the number of rival males that they will encounter. Current empirical evidence is mostly consistent with this scheme: in some cases it seems that traits that are associated with locating mates are favoured at low densities, with aggression related traits favoured at higher densities, and in other cases aggression is selected but as density increases less aggressive strategies become more common. There remain substantial differences between species, however, and I discuss how variation in mating system, in the costs of aggression and in the nature of sperm competition, plus ecological differences between species, can change the relationship between population density and the fitness consequences of aggressive and passive behavioural strategies. 相似文献
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27.
White Nicholas J Ashley Elizabeth A Recht Judith Delves Michael J Ruecker Andrea Smithuis Frank M Eziefula Alice C Bousema Teun Drakeley Chris Chotivanich Kesinee Imwong Mallika Pukrittayakamee Sasithon Prachumsri Jetsumon Chu Cindy Andolina Chiara Bancone Germana Hien Tran T Mayxay Mayfong Taylor Walter RJ von Seidlein Lorenz Price Ric N Barnes Karen I Djimdé Abdoulaye ter Kuile Feiko Gosling Roly Chen Ingrid Dhorda Mehul J Stepniewska Kasia Guérin Philippe Woodrow Charles J Dondorp Arjen M Day Nicholas PJ Nosten Francois H 《Malaria journal》2014,13(1):1-14
Background
Effective mating between laboratory-reared males and wild females is paramount to the success of vector control strategies aiming to decrease disease transmission via the release of sterile or genetically modified male mosquitoes. However mosquito colonization and laboratory maintenance have the potential to negatively affect male genotypic and phenotypic quality through inbreeding and selection, which in turn can decrease male mating competitiveness in the field. To date, very little is known about the impact of those evolutionary forces on the reproductive biology of mosquito colonies and how they ultimately affect male reproductive fitness.Methods
Here several male reproductive physiological traits likely to be affected by inbreeding and selection following colonization and laboratory rearing were examined. Sperm length, and accessory gland and testes size were compared in male progeny from field-collected females and laboratory strains of Anopheles gambiae sensu stricto colonized from one to over 25 years ago. These traits were also compared in the parental and sequentially derived, genetically modified strains produced using a two-phase genetic transformation system. Finally, genetic crosses were performed between strains in order to distinguish the effects of inbreeding and selection on reproductive traits.Results
Sperm length was found to steadily decrease with the age of mosquito colonies but was recovered in refreshed strains and crosses between inbred strains therefore incriminating inbreeding costs. In contrast, testes size progressively increased with colony age, whilst accessory gland size quickly decreased in males from colonies of all ages. The lack of heterosis in response to crossing and strain refreshing in the latter two reproductive traits suggests selection for insectary conditions.Conclusions
These results show that inbreeding and selection differentially affect reproductive traits in laboratory strains overtime and that heterotic ‘supermales’ could be used to rescue some male reproductive characteristics. Further experiments are needed to establish the exact relationship between sperm length, accessory gland and testes size, and male reproductive success in the laboratory and field settings. 相似文献28.
Identification of a 43-kDa polypeptide associated with acetylcholine receptor-enriched membranes as MM creatine kinase 总被引:1,自引:0,他引:1
M B Perryman J D Knell J Ifegwu R Roberts 《The Journal of biological chemistry》1985,260(16):9399-9404
Creatine kinase isoenzymes from Torpedo californica electric organ, skeletal muscle, and brain were purified and characterized. Torpedo electric organ and skeletal muscle creatine kinase have identical apparent Mr, electrophoretic mobility, and cyanogen bromide fragments. The electrophoretic mobility of the Torpedo creatine kinase was anodal as compared to mammalian MM creatine kinase. No creatine kinase isoenzyme with an electrophoretic mobility similar to mammalian BB creatine kinase was seen in any of the Torpedo tissues examined. Hybridization studies demonstrate the Torpedo electric organ creatine kinase to be composed of identical subunits and capable of producing an enzymatically active heterodimer when combined with canine BB creatine kinase. Creatine kinase from sucrose gradient-purified Torpedo electric organ acetylcholine receptor-rich membranes has an electrophoretic mobility identical with the cytoplasmic isoenzyme and an apparent Mr identical with mammalian MM creatine kinase. Western blot analysis showed Torpedo electric organ skeletal muscle creatine kinase and acetylcholine receptor-enriched membrane creatine kinase reacted with antiserum specific for canine MM creatine kinase. NH2-terminal amino acid sequence determinations show considerable sequence homology between human MM, Torpedo electric organ, chicken MM, and porcine MM creatine kinase. The acetylcholine receptor-associated creatine kinase is, therefore, identical with the cytoplasmic form from the electric organ and is composed of M-subunits. 相似文献
29.
P. Kása RW. Dames† Z. Rakonczay K. Gulya F. Joó‡ RJ. R. Wolff† 《Journal of neurochemistry》1985,44(5):1363-1372
gamma-Aminobutyric acid (GABA) was applied to the superior cervical ganglion (SCG) of CFY rats in vitro and in vivo, with or without implantation of a hypoglossal nerve, to evaluate the effects of these experimental interventions on the acetylcholine (ACh) system, which mainly serves the synaptic transmission of the preganglionic input. Long-lasting GABA microinfusion into the SCG in vivo apparently resulted in a "functional denervation." This treatment reduced the acetylcholinesterase (AChE; EC 3.1.1.7) activity by 30% (p less than 0.01) and transiently increased the number of nicotinic acetylcholine receptors, but had no significant effect on the choline acetyltransferase (acetyl-coenzyme A:choline-O-acetyltransferase; EC 2.3.1.6) activity, the ACh level, or the number of muscarinic acetylcholine receptors. The relative amounts of the different molecular forms of AChE did not change under these conditions. In vivo GABA application to the SCG with a hypoglossal nerve implanted in the presence of intact preganglionic afferent synapses exerted a significant modulatory effect on the AChE activity and its molecular forms. The "hyperinnervation" of the ganglia led to increases in the AChE activity (to 142.5%, p less than 0.01) and the 16S molecular form (to 200%, p less than 0.01). It is concluded that in vivo GABA microinfusion and GABA treatment in the presence of additional cholinergic synapses has a modulatory effect on the elements of the ACh system in the SCG of CFY rats. 相似文献
30.
Rocjard R. Kirby RJ. Berry D.A. Powers 《Biological journal of the Linnean Society. Linnean Society of London》1997,62(2):299-312
Genetic constitution in the intertidal gastropod Nucella lapillus (L.) influences shell shape, growth rate and physiology. Clinal variation in these traits along a 5 km stretch of coastline in south Devon can be related to environmental variation in temperature and desiccation stress. We have examined mtDNA variation along this shore to investigate whether the cline represents primary or secondary contact. Two distinct mtDNA haplotypes were found which exhibit coincident step clines with karyotypic, allozymic and phenotypic variation and covary with the environmental pressures of temperature and desiccation. These results are interpreted in the context of the wider scale distribution of genetic and phenotypic variation in N. lapillus. It is suggested that the shore studied may represent one of a number of regions of secondary contact within a mosaic hybrid zone in N. lapillus , where coadapted phenotypic variation correlates with habitat and the position of the clines represents an environmental transition. 相似文献