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531.
Pseudomonas sp. ATCC 27330 with 17-Dehydrogenase Activity: a Contaminant in an Endocrine Laboratory
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Steroidal conversion of testosterone to androstenedione was found mediated by a Pseudomonas species in a hospital endocrinology laboratory. 相似文献
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Thomas Luke Underwood Jim N. Adam Arne A. S. Richards Zoe T. Dugal Laurence Miller Karen J. Gilmour James P. 《Coral reefs (Online)》2020,39(1):55-60
Coral Reefs - An understanding of larval dispersal and connectivity in corals provides valuable insight into the processes of population maintenance and replenishment and is vital for effective... 相似文献
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Dawn Carnes Yasir Anwer Martin Underwood Geoff Harding Suzanne Parsons 《BMJ (Clinical research ed.)》2008,336(7636):142-145
Objective To explore the factors that influence older people’s decision making regarding use of topical or oral ibuprofen for their knee pain.Design Qualitative interview study nested within a randomised controlled trial and a patient preference study that compared advice to use oral or topical non-steroidal anti-inflammatory drugs (NSAIDs) for knee pain in older people.Setting 11 general practices.Participants 30 people aged ≥50 with knee pain. Results Participants’ decision making was influenced by their perceptions of the associated risk of adverse effects, presence of other illness, nature of their pain, advice received, and practicality. Although participants’ understanding of how the medications worked was sometimes poor their decision making about the use of NSAIDs seemed logical and appropriate. Participants’ model for treatment was to use topical NSAIDs for mild, local, and transient pain and oral NSAIDs for moderate to severe, generalised, and constant pain (in the absence of other more serious illness or risk of adverse effects). Participants showed marked tolerance and normalisation of adverse effects.Conclusion Participants had clear ideas about the appropriate use of oral and topical NSAIDs. Taking such views into account when prescribing may improve adherence, judgment of efficacy, and the doctor-patient relationship. Tolerance and normalisation of adverse effects in these patients indicate that closer monitoring of older people who use NSAIDs might be needed. 相似文献
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E. Ashworth Underwood 《BMJ (Clinical research ed.)》1948,1(4557):890-892