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111.
112.
The European Bioinformatics Institute web site: a new view 总被引:1,自引:0,他引:1
Lopez R Robinson S Kibria A Harte N Patel G Harper R Quevillon E Silventoinen V Kallio K Jokinen P 《Bioinformatics (Oxford, England)》2003,19(4):546-547
SUMMARY: The European Bioinformatics Institute (EBI), and outstation of the European Molecular Biology laboratory, has revamped its web site for the second time since 1997 in order to address increased user demand as well as establishing better uniformity and easier accessibility for the ever growing number of users and services it offers to the community. A GRID-like hardware infrastructure has been put in place to provide round the clock services in a redundant and reliable fashion. AVAILABILITY: http://www.ebi.ac.uk/ 相似文献
113.
Kolari Tiina H. M. Sallinen Antti Wolff Franziska Kumpula Timo Tolonen Kimmo Tahvanainen Teemu 《Ecosystems》2022,25(5):1166-1188
Ecosystems - Northern aapa mire complexes are characterized by patterned fens with flarks (wet fen surfaces) and bog zone margins with Sphagnum moss cover. Evidence exists of a recent increase in... 相似文献
114.
Harri M Kasai H Mori T Tornaeus J Savela K Peltonen K 《Journal of chromatography. B, Analytical technologies in the biomedical and life sciences》2007,853(1-2):242-246
8-hydroxy-2'-deoxyguanosine (8-OHdG) is a widely used biomarker of oxidative stress in research related to DNA, protein damage as well as lipid peroxidation. HPLC-MS/MS with electrospray ionization (ESI) and the use of isotopically labelled 8-OHdG as an internal standard allows a simple quantification of 8-OHdG in urine samples. HPLC separation utilized the peak cutting technique and a 1.5 mmx120 mm analytical anion exchange column. Novel method entails only minimal sample handling including the addition of a buffer and an internal standard followed by centrifugation before the samples are ready for analysis. The levels of 8-OHdG in human urine samples (n=246) varied from 0.16 to 16.48 microg/L and the corresponding creatinine-normalized values were ranged from 0.49 to 14.27 microg of 8-OHdG/g creatinine. The correlation between the developed HPLC-MS/MS method and the existing HPLC-EC method was good with an R2 value of 0.8707. 相似文献
115.
116.
Determinants of cooperation include ingroup vs. outgroup membership, and individual traits, such as prosociality and trust. We investigated whether these factors can be overridden by beliefs about people’s trust. We manipulated the information players received about each other’s level of general trust, “high” or “low”. These levels were either measured (Experiment 1) or just arbitrarily assigned labels (Experiment 2). Players’ choices whether to cooperate or defect in a stag hunt (or an assurance game)—where it is mutually beneficial to cooperate, but costly if the partner should fail to do so—were strongly predicted by what they were told about the other player’s trust label, as well as by what they were told that the other player was told about their own label. Our findings demonstrate the importance for cooperation in a risky coordination game of both first- and second-order beliefs about how much people trust each other. This supports the idea that institutions can influence cooperation simply by influencing beliefs. 相似文献
117.
Tapio Palj?rvi Pekka Martikainen Tiina Pensola Taina Leinonen Kimmo Herttua Pia M?kel? 《PloS one》2015,10(5)
BackgroundLong-term employment trajectories of young problem drinkers are poorly understood.MethodsWe constructed retrospective labour market participation histories at ages 18–34 of 64 342 persons born in 1969–1982. Beginning from the year of each subject’s 18th birthday, we extracted information from the records of Statistics Finland on educational attainment, main type of economic activity, months in employment, and months in unemployment for a minimum of seven years (range 7–16 years). We used information on the timing of alcohol-related hospitalizations and deaths in the same period to define problem drinkers with early onset limited course, early onset persistent course, and late onset problem drinking.ResultsEarly onset limited course problem drinkers improved their employment considerably by age, whereas early onset persistent problem drinkers experienced a constant decline in their employment by age. From the age of 18 to 34, early onset persistent problem drinkers were in employment merely 12% of the time, in comparison with 39% among the early onset limited course problem drinkers, and 58% among the general population.ConclusionsThese results indicate that young adults who were retrospectively defined as having early onset persistent course problem drinking were extensively marginalized from the labour market early on during their life course, and that their employment trajectory was significantly worse compared to other problem drinkers. 相似文献
118.
Contrasting trends of butterfly species preferring semi-natural grasslands,field margins and forest edges in northern Europe 总被引:3,自引:1,他引:2
Mikko Kuussaari Janne Heliölä Juha Pöyry Kimmo Saarinen 《Journal of Insect Conservation》2007,11(4):351-366
Indicator classifications help us to focus on the most relevant groups of species in monitoring the effects of land use changes
on biodiversity. We studied changes in distribution area of 74 butterfly species preferring one of the three common habitats
of boreal agricultural landscapes: semi-natural grasslands (35 species), arable field margins (7) and forest edges (32). Using
extensive atlas data from four time periods during the last 50 years in Finland, we quantified trends in the occupancy of
the species in 10 km grid squares, and classified them into four classes: declining (23), stable (17), increasing (27) and
fluctuating (7) species. Trends among the species favouring three habitats were different: 60% of the species of semi-natural
grasslands had declined, whereas 86% of the species typical of open field margins had increased. An increase also predominated
in species associated with forest edges. Declining and increasing species differed in three ecological characteristics: increasing
species were more mobile, utilized a wider range of habitats and, based on their larval host plants, lived in more eutrophic
habitats than declining species. Species overwintering as adults showed more positive trends in occupancy than species overwintering
as eggs, larvae or pupae. Observed trends in occupancy are in good agreement with long-term changes in land use and habitat
availability in Finland: a long-continued decrease in the area of semi-natural grasslands and an increased amount of open
forest edges and clearings due to modern forestry during the past 50 years. 相似文献
119.
Genetic relatedness inChaenomeles was studied by RAPD analysis in 42 plants representing accessions of three wild species and one hybrid taxon. Amplification with 17 primers yielded a total of 156 polymorphic RAPD bands. Estimates of genetic relatedness suggest thatC. cathayensis andC. japonica are the most distantly related species, and that the former is comparatively homogeneous.Chaenomeles speciosa, which may have arisen through hybridization betweenC. cathayensis andC. japonica, takes an intermediate position between these two species. Analysis of diagnostic bands demonstrate that neitherC. speciosa norC. ×superba has any bands that do not occur in at least one ofC. cathayensis orC. japonica. Moreover,C. speciosa and the partly overlapping taxonC. ×superba are comparatively heterogeneous, which is also in accordance with a hybrid origin. Intraspecific variation was studied mainly inC. japonica; plants obtained from different sources of material formed well separated groups in the cluster analysis. 相似文献
120.
Scaling distributional patterns of butterflies across multiple scales: Impact of range history and habitat type 下载免费PDF全文
Juha Pöyry Risto K. Heikkinen Janne Heliölä Mikko Kuussaari Kimmo Saarinen 《Diversity & distributions》2018,24(10):1453-1463