全文获取类型
收费全文 | 206篇 |
免费 | 6篇 |
出版年
2022年 | 1篇 |
2021年 | 2篇 |
2020年 | 5篇 |
2019年 | 3篇 |
2018年 | 9篇 |
2017年 | 2篇 |
2016年 | 2篇 |
2015年 | 3篇 |
2014年 | 4篇 |
2013年 | 5篇 |
2012年 | 10篇 |
2011年 | 9篇 |
2010年 | 9篇 |
2009年 | 4篇 |
2008年 | 16篇 |
2007年 | 3篇 |
2006年 | 11篇 |
2005年 | 8篇 |
2004年 | 15篇 |
2003年 | 19篇 |
2002年 | 9篇 |
2001年 | 8篇 |
2000年 | 15篇 |
1999年 | 2篇 |
1998年 | 2篇 |
1996年 | 1篇 |
1991年 | 1篇 |
1989年 | 2篇 |
1988年 | 1篇 |
1986年 | 1篇 |
1984年 | 1篇 |
1983年 | 2篇 |
1982年 | 1篇 |
1979年 | 1篇 |
1977年 | 1篇 |
1976年 | 2篇 |
1974年 | 2篇 |
1973年 | 1篇 |
1972年 | 4篇 |
1971年 | 4篇 |
1970年 | 4篇 |
1969年 | 2篇 |
1968年 | 1篇 |
1967年 | 1篇 |
1966年 | 1篇 |
1965年 | 1篇 |
1961年 | 1篇 |
排序方式: 共有212条查询结果,搜索用时 31 毫秒
31.
Khokhlova VN Karelin AA Belotserkovskiĭ MV Stetsiuk OU 《Antibiotiki i khimioterapii͡a》2011,56(5-6):19-29
The data on the microbiological investigation of clinical materials from patients with complicated skin and soft tissue infections in 6 European countries were analysed. The analysis of the bacterial pathogens spectrum provided the microbial view and efficient use of novel antimicrobials in clinical trials. 相似文献
32.
The effect of temperature stress on the cytosol carbohydrate composition of fungi belonging to various systematic groups was
investigated. InMucorales representatives (subkingdomEomycota, phylumArchetnycota, classZygomycetes), adaptation to hypo- and hyperthermia occurs via the regulation of trehalose synthesis, although inositol is also involved
in these processes inBlakeslea trispora. InAscomycota (subkingdomNeomycota), oversynthesis of mannitol and glycerol occurs under hypothermia, whereas oversynthesis of trehalose and inositol takes place
under hyperthermia.Basidiomycota (subkingdomNeomycota) use two pathways of biochemical adaptation, depending on the cytosol carbohydrate composition. In the absence of sucrose,
glycerol and arabitol are involved in the adaptation to hyperthermia; trehalose accumulates under hypothermic conditions (type
I of regulation). Type II regulation (revealed inPleurotus ostreatus) involves sucrose rather than glycerol or arabitol. The data obtained are discussed in terms of fungal systematics and phylogeny. 相似文献
33.
Christian Kiffner Michal Stanko Serge Morand Irina S. Khokhlova Georgy I. Shenbrot Anne Laudisoit Herwig Leirs Hadas Hawlena Boris R. Krasnov 《Oecologia》2013,173(3):1009-1022
The distribution of parasites among individual hosts is characterised by high variability that is believed to be a result of variations in host traits. To find general patterns of host traits affecting parasite abundance, we studied flea infestation of nine rodent species from three different biomes (temperate zone of central Europe, desert of Middle East and tropics of East Africa). We tested for independent and interactive effects of host sex and body mass on the number of fleas harboured by an individual host while accounting for spatial clustering of host and parasite sampling and temporal variation. We found no consistent patterns of the effect of host sex and body mass on flea abundance either among species within a biome or among biomes. We found evidence for sex-biased flea infestation in just five host species (Apodemus agrarius, Myodes glareolus, Microtus arvalis, Gerbillus andersoni, Mastomys natalensis). In six rodent species, we found an effect of body mass on flea abundance (all species mentioned above and Meriones crassus). This effect was positive in five species and negative in one species (Microtus arvalis). In M. glareolus, G. andersoni, M. natalensis, and M. arvalis, the relationship between body mass and flea abundance was mediated by host sex. This was manifested in steeper change in flea abundance with increasing body mass in male than female individuals (M. glareolus, G. andersoni, M. natalensis), whereas the opposite pattern was found in M. arvalis. Our findings suggest that sex and body mass are common determinants of parasite infestation in mammalian hosts, but neither of them follows universal rules. This implies that the effect of host individual characteristics on mechanisms responsible for flea acquisition may be manifested differently in different host species. 相似文献
34.
Tatiana Kulakovskaya Lyubov Ryazanova Anton Zvonarev Galina Khokhlova Vladimir Ostroumov Mikhail Vainshtein 《Folia microbiologica》2018,63(4):507-510
Yeasts Cryptococcus humicola accumulated cadmium, cobalt, and iron (~?50, 17, and 4% of the content in the medium, respectively) from the medium containing glucose, phosphate, and 2 mmol/L of metal salts. The effects of metal absorption on the levels of orthophosphate (Pi) and inorganic polyphosphate (polyP) varied for the metals under study. The levels of Pi and polyP increased in the case of cadmium and cobalt, respectively. In the case of iron, no changes in the levels of Pi and polyP were observed. Multiple DAPI-stained polyP inclusions were observed in the cytoplasm of cadmium-containing cells. The intensity of DAPI staining of the cell wall especially increased in case of cobalt and iron accumulation. 相似文献
35.
Mikhaleva I. I. Prudchenko I. A. Onoprienko L. V. Lobanov A. V. Rodionov A. N. Tukhovskaya E. A. Khokhlova O. N. Shykhutdinova E. R. Murashev A. N. Ivanov V. T. 《Russian Journal of Bioorganic Chemistry》2018,44(6):631-639
Russian Journal of Bioorganic Chemistry - We performed a computer search for the DSIP homologous structures in the protein data bases and found the KND peptide (WKGGDNASGE), which was closely... 相似文献
36.
Trait‐based and phylogenetic associations between parasites and their hosts: a case study with small mammals and fleas in the Palearctic
下载免费PDF全文
![点击此处可从《Oikos》网站下载免费的PDF全文](/ch/ext_images/free.gif)
We investigated the associations between ecological (density, shelter structure), morphological (body mass, hair morphology) and physiological traits (basal metabolic rate) of small mammals and ecological (seasonality of reproduction, microhabitat preferences, abundance, host specificity) and morphological (presence and number of combs) traits of their flea parasites that shape host selection processes by fleas. We adapted the extended version of the three‐table ordination and linked species composition of flea assemblages of host species with traits and phylogenies of both hosts and fleas. Fleas with similar trait values, independent of phylogenetic affinities, were clustered on the same host species. Fleas possessing certain traits selected hosts possessing certain traits. Fleas belonging to the same phylogenetic lineage were found on the same host more often than expected by chance. Certain phylogenetic lineages of hosts harbored certain phylogenetic lineages of fleas. The process of host selection by fleas appeared to be determined by reciprocal relationships between host and flea traits, as well as between host and flea phylogenies. We concluded that the connection between host and flea phylogenies, coupled with the connection between host and flea traits, suggests that the species compositions of the host spectra of fleas were driven by the interaction between historical processes and traits. 相似文献
37.
T D Khokhlova M M Ianina S I Dikhtirev Iu S Nikitin B I Kurganov 《Prikladnaia biokhimiia i mikrobiologiia》1983,19(3):378-382
Urease was immobilized on macroporous silicas using gamma-aminopropyl triethoxysilane and glutaraldehyde. The amount of protein on the surface, the structure of pores of the support and the purity of the initial enzyme were varied, the enzymic activity of the immobilized preparations being controlled. After the immobilization of sufficiently large quantities of the enzyme (about 3 mg protein per m2 support) about 35% of the specific activity was retained. The maximum activity per unit weight of the support was observed for silicagels and silochromes with the mean diameter of pores 70-90 nm and the specific surface area about 70 m2/g. The use of purified urease produced highly active preparations of the immobilized enzyme (17,000 U per g dry support). Freeze-drying of the immobilized enzyme in the presence of sorbitol yielded dry preparations retaining their activity. 相似文献
38.
39.
40.
Arbiv A Khokhlova IS Ovadia O Novoplansky A Krasnov BR 《Journal of evolutionary biology》2012,25(6):1140-1148
Using experimentally induced disruptive selection, we tested two hypotheses regarding the evolution of specialization in parasites. The 'trade-off' hypothesis suggests that adaptation to a specific host may come at the expense of a reduced performance when exploiting another host. The alternative 'relaxed selection' hypothesis suggests that the ability to exploit a given host would deteriorate when becoming obsolete. Three replicate populations of a flea Xenopsylla ramesis were maintained on each of two rodent hosts, Meriones crassus and Dipodillus dasyurus, for nine generations. Fleas maintained on a specific host species for a few generations substantially decreased their reproductive performance when transferred to an alternative host species, whereas they generally did not increase their performance on their maintenance host. The results support the 'relaxed selection' hypothesis of the evolution of ecological specialization in haematophagous ectoparasites, while suggesting that trade-offs are unlikely drivers of specialization. Further work is needed to study the extent by which the observed specializations are based on epigenetic or genetic modifications. 相似文献