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11.
L K Riago A M Nurk A Ia Korneev L Kh Allikmets 《Biulleten' eksperimental'no? biologii i meditsiny》1982,94(11):58-59
(+/-) Fenibut beta-phenyl-GABA) was not able to displace 3H-GABA in Na+ independent GABA binding (IC50 greater than 250 microM). Nevertheless, (+/-) fenibut and (+/-) baclofen effectively displaced 3H-GABA in Ca2+ dependent GABA binding in the presence of 50 microM (+) bicuculline. (+/-) Fenibut was less potent in this respect. It is suggested that fenibut may act via bicuculline-insensitive GABA receptors. 相似文献
12.
A. Yu. Tsibulevsky T. K. Dubovaya A. I. Shchegolev A. I. Sergeev A. V. Bykov Kh. K. Gadzhieva 《Biology Bulletin》2005,32(6):590-596
Intoxication with bacterial lipopolysaccharide (endotoxin) is accompanied by considerable rearrangements in the systems of blood microcirculation and water metabolism of the liver. These rearrangements are manifested as increased sinusoid area, changed total area of the cytoplasm and nuclei as well as the nucleocytoplasmic ratio in hepatocytes, increased content of total water in the organ, and changed magnetic relaxation properties (spin-lattice and spin-spin relaxation times). Preliminary parasympathetic denervation of the liver (vagotomy) changes the pattern of the organ response to bacterial endotoxin poisoning as indicated by the kinetics of studied morphological and biophysical parameters. 相似文献
13.
R Kh Iafaev V V Dudareva T G Ivanova E B Kaganer L V Loseva 《Zhurnal mikrobiologii, epidemiologii, i immunobiologii》1986,(11):16-20
The short-term prognosis of the epidemic situation requires the establishment of the system of constant surveillance, which takes into account the data on morbidity rates for several years, both total and in various age groups, the data on the morbidity level and its changes, induced by meningococci of the epidemic group, in the IV quarter of the year, the data on the level of carriership among the indicator groups of the population in this period, as well as the data on changes in antibody titers in the sera of donor blood samples taken in summer and in December. 相似文献
14.
T M Zheltikova V M Berzhets A D Petrova-Nikitina A Kh Kanchurin 《Zhurnal mikrobiologii, epidemiologii, i immunobiologii》1986,(6):80-83
The acarological+ study of dust samples from the homes of allergic patients and normal persons in Moscow mite antigens were detected, respectively, in 66.7% and 38.1% of homes. The indirect mast cell degranulation test and the brain gliacyte volume change test in white rats gave similar results. The occurrence of Dermatophagoides pteronyssinus was approximately twice as great of D. farinae, and the numerical prevalence of the former species over the latter one was 1.3-fold. Dermatophagoides mites occurred in the homes of allergic patients 1.8-2.3 times as frequently as in the homes of normal persons. 相似文献
15.
Some properties of hexameric purine nucleoside phosphorylase II (EC 2.4.2.1) from Escherichia coli K-12 were studied. The enzyme obeys the Michaelis-Menten kinetics with respect to purine substrates (Km for inosine, deoxyinosine and hypoxanthine are equal to 492, 106 and 26.6 microM, respectively) and exhibits negative kinetic cooperativity towards phosphate and ribose-1-phosphate. The Hill coefficient is equal to approximately 0.5 for both substrates. Hexameric purine nucleoside phosphorylase II is not a metal-dependent enzyme; its activity is inhibited by Cu2+, Zn2+, Ni2+ and SO4(2-). The enzyme is the most stable at pH 6.0; it contains essential thiol groups. All substrates partly protect the enzyme against inactivation by 5.5'-dithiobis(2-nitrobenzoic acid) and heat-inactivation and, with the exception of phosphate-against inactivation by p-chloromercuribenzoate. Hypoxanthine, especially in combination with phosphate, afford the best protection against inactivation. 相似文献
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18.
V. S. Kurbanismailov O. A. Omarov G. B. Ragimkhanov M. Kh. Gadzhiev M. G. Bairkhanova A. J. Kattaa 《Plasma Physics Reports》2011,37(13):1166-1172
The experimental results on the formation and development of initial stages of an impulse breakdown in atmospheric-pressure
argon at townsend and streamer breakdown mechanisms for different initial conditions are presented. A streamer channel is
shown to be initiated by bright luminescence formed at the point of critical avalanche amplification at different distances
from the cathode depending on overvoltage. Prebreakdown currents are experimentally measured for the townsend and streamer
breakdown mechanisms and peculiarities of spark channel formation for these mechanisms are studied. 相似文献
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20.
Kh S Khamitov E I Bogdanov F A Khabirov V Z Khamidullina 《Biulleten' eksperimental'no? biologii i meditsiny》1983,96(11):24-26
Experiments with 22 rats have shown that the anterior tibial muscle in the stage of incomplete reinnervation is marked by decreased force and retardation of the semi-relaxation of an isometric contraction. In completely reinnervated muscles, the changes in the contractility are determined by the degree of nerve damage. The group of animals with the sciatic nerve injury demonstrated the contractility characteristic of a slower muscle, in contrast to the group with the fibular nerve damage. 相似文献