全文获取类型
收费全文 | 802篇 |
免费 | 105篇 |
出版年
2023年 | 5篇 |
2022年 | 14篇 |
2021年 | 24篇 |
2020年 | 6篇 |
2019年 | 25篇 |
2018年 | 16篇 |
2017年 | 13篇 |
2016年 | 20篇 |
2015年 | 43篇 |
2014年 | 34篇 |
2013年 | 41篇 |
2012年 | 65篇 |
2011年 | 57篇 |
2010年 | 24篇 |
2009年 | 38篇 |
2008年 | 42篇 |
2007年 | 39篇 |
2006年 | 24篇 |
2005年 | 23篇 |
2004年 | 24篇 |
2003年 | 26篇 |
2002年 | 17篇 |
2001年 | 10篇 |
2000年 | 7篇 |
1999年 | 11篇 |
1998年 | 5篇 |
1997年 | 7篇 |
1996年 | 9篇 |
1994年 | 7篇 |
1993年 | 5篇 |
1992年 | 12篇 |
1991年 | 7篇 |
1990年 | 14篇 |
1989年 | 7篇 |
1988年 | 15篇 |
1987年 | 10篇 |
1986年 | 11篇 |
1985年 | 15篇 |
1984年 | 7篇 |
1983年 | 9篇 |
1981年 | 5篇 |
1980年 | 5篇 |
1979年 | 12篇 |
1978年 | 9篇 |
1976年 | 9篇 |
1975年 | 6篇 |
1974年 | 8篇 |
1970年 | 10篇 |
1969年 | 5篇 |
1968年 | 9篇 |
排序方式: 共有907条查询结果,搜索用时 218 毫秒
861.
862.
863.
864.
Patricia E. Lpez‐Calcagno Stuart Fisk Kenny L. Brown Simon E. Bull Paul F. South Christine A. Raines 《Plant biotechnology journal》2019,17(1):141-151
Photorespiration is essential for C3 plants, enabling oxygenic photosynthesis through the scavenging of 2‐phosphoglycolate. Previous studies have demonstrated that overexpression of the L‐ and H‐proteins of the photorespiratory glycine cleavage system results in an increase in photosynthesis and growth in Arabidopsis thaliana. Here, we present evidence that under controlled environment conditions an increase in biomass is evident in tobacco plants overexpressing the H‐protein. Importantly, the work in this paper provides a clear demonstration of the potential of this manipulation in tobacco grown in field conditions, in two separate seasons. We also demonstrate the importance of targeted overexpression of the H‐protein using the leaf‐specific promoter ST‐LS1. Although increases in the H‐protein driven by this promoter have a positive impact on biomass, higher levels of overexpression of this protein driven by the constitutive CaMV 35S promoter result in a reduction in the growth of the plants. Furthermore in these constitutive overexpressor plants, carbon allocation between soluble carbohydrates and starch is altered, as is the protein lipoylation of the enzymes pyruvate dehydrogenase and alpha‐ketoglutarate complexes. Our data provide a clear demonstration of the positive effects of overexpression of the H‐protein to improve yield under field conditions. 相似文献
865.
866.
867.
The morphology of mature larvae of Sisyra nigra was studied and documented with a broad spectrum of techniques. Special emphasis is on the cephalic anatomy and on the digestive tract. Cephalic structures are highly modified, with numerous autapomorphic conditions, including a globular head capsule, an extended area with large cornea lenses, a massive tentorium, a strongly developed prepharyngeal pumping apparatus with a horizontal arrangement of dilators, a sharp bend between the prepharynx and pharynx, and an unusual filter apparatus at the entrance of the large crop. The thoracic and abdominal muscle sets, and the legs are largely unmodified. Postcephalic apomorphies are conspicuous tergal setiferous tubercles, trifid setiferous pleural projections, single pretarsal claws, zigzag-shaped abdominal tracheal gills, and a dense vestiture of setae on the terminal abdominal segments. Mandibulo-maxillary stylets curved outwards are an unusual apomorphy also found in the semiaquatic larvae of Osmylidae. Semiaquatic or aquatic habits and secondarily multisegmented antennae are potential synapomorphies of these two groups and Nevrorthidae (Osmyloidea). A sistergroup relationship between Sisyridae and Nevrorthidae suggests that fully aquatic habits of larvae may be a synapomorphy of both families. A specialized terminal antennal seta is a potential groundplan apomorphy of Neuroptera, with secondary loss in Nevrorthidae and Ithonidae + Myrmeleontiformia, respectively. A trumpet-shaped empodium is likely an apomorphy of Neuroptera excluding Coniopterygidae and Osmyloidea, and the secondary loss an apomorphy of Ithonidae on one hand, and Myrmeleontiformia excl. Psychopsidae on the other. 相似文献
868.
Meg L. Martin Kenny J. Travouillon Emma Sherratt Patricia A. Fleming Natalie M. Warburton 《Journal of morphology》2019,280(12):1900-1915
The close association between muscle and bone is broadly intuitive; however, details of the covariation between the two has not been comprehensively studied. Without quantitative understanding of how muscle anatomy influences bone shape, it is difficult to draw conclusions of the significance of many morphological traits of the skeleton. In this study, we investigated these relationships in the Quenda (Isoodon fusciventer), a scratch-digging marsupial. We quantified the relationships between forelimb muscle anatomy and bone shape for animals representing a range of body masses (124–1,952 g) using two-block partial least square analyses. Muscle anatomy was quantified as muscle mass and physiological cross-sectional area (PCSA), and we used two morphometric methods to characterize bone shape: seven indices of linear bone proportions, and landmarks analysis. Bone shape was significantly correlated with body mass, reflecting allometric bone growth. Of the seven bone indices, only shoulder moment index (SMI) and ulna robustness index (URI) showed a significant covariation with muscle anatomy. Stronger relationships between muscle anatomy and forelimb bone shape were found using the landmark coordinates: muscle mass and PCSA were correlated with the geometric shape of the scapula, humerus, and third metacarpal, but to a lesser extent with shape of the ulna. Overall, our data show that landmark coordinates are more sensitive than bone indices to capturing shape changes evident throughout ontogeny, and is therefore a more appropriate method to investigate covariation with forelimb muscle anatomy. Single-species studies investigating ontogeny require refined methods to accurately develop understanding of the important relationships between muscle force generation and bone shape remodeling. Landmark analyses provide such a method. 相似文献
869.
Abnormal fatty acid profile in chronic hemodialysis patients: possible deficiency of essential fatty acids 总被引:2,自引:0,他引:2
Plasma fatty acid profiles from maintenance hemodialysis patients (n = 9) were compared with those from healthy volunteers (n = 9). Hemodialysis patients had significantly higher levels of oleic acid, 15.3 +/- 1.1 vs. 8.9 +/- 0.6% (p less than 0.0001), and lower levels of arachidonic acid (6.0 +/- 0.5 vs. 8.4 +/- 0.3%, p less than 0.0009). Linolenic and linoleic acids, the essential fatty acid and precursors of arachidonic acid, were also significantly lower than normal in the dialysis group. These data show that dialysis patients have fatty acid abnormalities suggesting relative depletion of essential fatty acids. These observations are important because these abnormalities may play an important role in the pathogenesis of some common clinical conditions associated with uremia, such as a constellation of skin problems, fragility of erythrocytes, lipid anomalies and hormonal aberrations. 相似文献
870.
Achatin-I, an endogenous neuroexcitatory tetrapeptide from Achatina fulica Férussac containing a D-amino acid residue 总被引:2,自引:0,他引:2
Y Kamatani H Minakata P T Kenny T Iwashita K Watanabe K Funase X P Sun A Yongsiri K H Kim P Novales-Li 《Biochemical and biophysical research communications》1989,160(3):1015-1020
A tetrapeptide named achatin-I was purified from the suboesophageal and cerebral ganglia of the African giant snail Achatina fulica Férussac, and evoked a potent neuroexcitatory effect. The amino acid sequence of achatin-I is Gly-D-Phe-Ala-Asp. Achatin-I induced a voltage-dependent inward current, due to Na+, on the identifiable giant neuron, periodically oscillating neuron (PON), of the same snail. All possible isomers of achatin-I were synthesized using the solid-phase method. The sensitivity of the neuron to achatin-I and its isomers was strictly stereospecific; among the various isomers, only achatin-I showed marked effects (ED50 = 2.29 x 10(-6)M), while Gly-D-Phe-D-Ala-Asp, the synthetic D-Ala-isomer, was less than 10(-3) active. 相似文献