全文获取类型
收费全文 | 63493篇 |
免费 | 5541篇 |
国内免费 | 50篇 |
专业分类
69084篇 |
出版年
2023年 | 304篇 |
2022年 | 667篇 |
2021年 | 1244篇 |
2020年 | 866篇 |
2019年 | 957篇 |
2018年 | 1347篇 |
2017年 | 1125篇 |
2016年 | 1879篇 |
2015年 | 2741篇 |
2014年 | 2723篇 |
2013年 | 3353篇 |
2012年 | 4005篇 |
2011年 | 3777篇 |
2010年 | 2312篇 |
2009年 | 2218篇 |
2008年 | 2759篇 |
2007年 | 2719篇 |
2006年 | 2502篇 |
2005年 | 2791篇 |
2004年 | 2719篇 |
2003年 | 2286篇 |
2002年 | 1865篇 |
2001年 | 1638篇 |
2000年 | 1556篇 |
1999年 | 1385篇 |
1998年 | 657篇 |
1997年 | 616篇 |
1996年 | 654篇 |
1995年 | 526篇 |
1994年 | 532篇 |
1993年 | 512篇 |
1992年 | 1061篇 |
1991年 | 936篇 |
1990年 | 881篇 |
1989年 | 859篇 |
1988年 | 850篇 |
1987年 | 769篇 |
1986年 | 709篇 |
1985年 | 698篇 |
1984年 | 647篇 |
1983年 | 506篇 |
1982年 | 383篇 |
1981年 | 369篇 |
1980年 | 349篇 |
1979年 | 493篇 |
1978年 | 412篇 |
1977年 | 345篇 |
1975年 | 320篇 |
1974年 | 341篇 |
1973年 | 338篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
81.
The stoichiometric palmitoyllysophosphatidylcholine (lysoPC)/gramicidin (4:1, mol/mol) lamellar complex (Killian, J.A., De Kruijff, B., Van Echteld, C.J.A., Verkleij, A.J., Leunissen-Bijvelt, J. and De Gier, J. (1983) Biochim. Biophys. Acta 728, 141-144) is a useful model system to investigate the various aspects of lipid protein interactions. To study the effect of gramicidin on local order and motion of 1-palmitoyl-sn-glycero-3-phosphocholine (lysoPC) we employed 31P and 2H nuclear magnetic resonance (NMR) using selectively deuterated lysoPC's and we compared the results to those obtained for lysoPC in bilayers with cholesterol (1:1, mol/mol) and dipalmitoylphosphatidylcholine (DPPC) (1:4, mol/mol). 2H-NMR experiments on acyl chain deuterated lysoPC showed similar quadrupole splittings in the liquid crystalline state for the lysoPC/DPPC and the lysoPC/gramicidin samples. In the lysoPC/cholesterol sample an increase of the quadrupole splitting was found. T1 measurements showed that gramicidin decreases the lysoPC acyl chain motion, especially at the C12 position. In the lysoPC/cholesterol sample an increase of motion was observed as compared to lysoPC in fluid bilayers of DPPC. 31P-NMR and 2-H-NMR measurements of lysoPC, deuterated at the alpha- and beta-position of the choline moiety, indicated an increase in headgroup flexibility in all samples as compared to the parent compound DPPC. In addition, a change in headgroup conformation was observed. The alpha- and beta-segments in all samples exhibited concerted motion. It was found that also in the polar headgroup gramicidin induces a decrease of the rate of motion. 相似文献
82.
83.
84.
Jeroen M. G. Stevens Hilde Vervaecke Han de Vries Linda van Elsacker 《International journal of primatology》2007,28(6):1417-1430
Bonobos have a reputation as a female-dominated and egalitarian species. We examined the 2 aspects of dominance in 6 captive
bonobo groups. Females do not consistently evoke submission from all males in all contexts. Though females occupy the highest-ranking
positions in the dominance hierarchy, there are in each group males that obtain rather high ranks and are able to dominate
≥1 female. Thus female dominance is not complete and hierarchies can be better described as nonexclusive female dominance.
We studied egalitarianism by measuring linearity and steepness of dominance hierarchies. The hierarchies of all groups are
highly linear. Hierarchies among males are steeper than among females. On average, male bonobos are more despotic than females,
but females too can have despotic relations, both with other females and with males. Hence one can call bonobos in captivity
semidespotic rather than egalitarian. 相似文献
85.
Martin T. R. Kuiper Marijke Holtrop Hans de Vries 《Molecular & general genetics : MGG》1988,213(2-3):519-528
86.
87.
88.
89.
90.
Female sex steroid induced epithelial changes in the gallbladder of the ovariectomized Syrian hamster. 总被引:1,自引:0,他引:1
Ovariectomized Syrian hamsters treated by female sex steroids during a 1-month period show gallbladder surface epithelial changes in the fundic area consistent with apical bulging and decapitations of the epithelial cells. These events were detected in the infundibulum and the fundic or body regions of estrogen- and estrogen+progesterone-treated hamsters. In control hamsters, these events were restricted to the region in the vicinity of the bile duct. Following steroid treatment, intraluminal deposits detected resembled Ca-bilirubinate deposits described in previous studies while decapitations are similar to endometrial epithelium changes associated with hormonal physiological changes or treatments. Moreover some small electron-dense deposits are comparable to those found in human cholesterol gallstones. This report indicates that, besides an alteration in bile composition, cell fragments originating from the surface epithelium of the bile duct and/or of the gallbladder mucosal epithelium could participate in gallstone nucleation. 相似文献