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11.
Baquero MR Nilsson AI Turrientes Mdel C Sandvang D Galán JC Martínez JL Frimodt-Møller N Baquero F Andersson DI 《Journal of bacteriology》2004,186(16):5538-5542
Polymorphisms in the rifampin resistance mutation frequency (f) were studied in 696 Escherichia coli strains from Spain, Sweden, and Denmark. Of the 696 strains, 23% were weakly hypermutable (4 x 10(-8) < or = f < 4 x 10(-7)), and 0.7% were strongly hypermutable (f > or = 4 x 10(-7)). Weak mutators were apparently more frequent in southern Europe and in blood isolates (38%) than in urinary tract isolates (25%) and feces of healthy volunteers (11%). 相似文献
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Shifting the life-history paradigm: discovery of novel habitat use by hawksbill turtles 总被引:1,自引:0,他引:1
Gaos AR Lewison RL Yañez IL Wallace BP Liles MJ Nichols WJ Baquero A Hasbún CR Vasquez M Urteaga J Seminoff JA 《Biology letters》2012,8(1):54-56
Adult hawksbill turtles (Eretmochelys imbricata) are typically described as open-coast, coral reef and hard substrate dwellers. Here, we report new satellite tracking data on female hawksbills from several countries in the eastern Pacific that revealed previously undocumented behaviour for adults of the species. In contrast to patterns of habitat use exhibited by their Caribbean and Indo-Pacific counterparts, eastern Pacific hawksbills generally occupied inshore estuaries, wherein they had strong associations with mangrove saltwater forests. The use of inshore habitats and affinities with mangrove saltwater forests presents a previously unknown life-history paradigm for adult hawksbill turtles and suggests a potentially unique evolutionary trajectory for the species. Our findings highlight the variability in life-history strategies that marine turtles and other wide-ranging marine wildlife may exhibit among ocean regions, and the importance of understanding such disparities from an ecological and management perspective. 相似文献
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Antibiotics and antibiotic resistance in water environments 总被引:9,自引:0,他引:9
Antibiotic-resistant organisms enter into water environments from human and animal sources. These bacteria are able to spread their genes into water-indigenous microbes, which also contain resistance genes. On the contrary, many antibiotics from industrial origin circulate in water environments, potentially altering microbial ecosystems. Risk assessment protocols for antibiotics and resistant bacteria in water, based on better systems for antibiotics detection and antibiotic-resistance microbial source tracking, are starting to be discussed. Methods to reduce resistant bacterial load in wastewaters, and the amount of antimicrobial agents, in most cases originated in hospitals and farms, include optimization of disinfection procedures and management of wastewater and manure. A policy for preventing mixing human-originated and animal-originated bacteria with environmental organisms seems advisable. 相似文献
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Effects of forest fragmentation on European birds: implications of regional differences in species richness 总被引:2,自引:0,他引:2
Aim In this paper, we adopted a large‐scale approach to evaluate the effect of regional richness of forest birds on the number of bird species retained by forest fragments in several localities across Europe. Location We studied bird assemblages in fourteen forest archipelagos embedded in agricultural matrices from southern Norway to central Spain. Tree composition varied from oak and beech forests of the northern localities to oak and pine xerophitic woodlands of the southern ones. The number of fragments in each forest archipelago ranged from eighteen to 211. Methods We used the Gleason equation (s = a + z log A; where s and A are, respectively, the species richness and size of forest fragments and z the rate of species loss) to estimate the species richness for 1‐ and 15‐ha fragments in each archipelago. The regional richness of forest birds was estimated by modelling the geographical distribution of species richness in the European atlas of breeding birds. Results The latitudinal distribution of regional richness displayed a convex form, with the highest values being in central Europe. Along this gradient, the number of species retained by fragments and the rate of species loss was positively related to regional richness. In addition, the percentage of the regional pool of species sampled by fragments decreased in the southern localities. Main conclusions Relationships between regional richness of forest birds and richness in fragments seem to explain why fragments in central Europe shelter more species than their southern counterparts. The decreased ability of southern forest fragments to sample the regional richness of forest birds, could be explained as an effect of the low abundance of many species in the Mediterranean, which could depress their ability to prevent extinction in fragments by a rescue effect. Alternatively, high beta diversity in the Mediterranean could produce undersampling by fragments of the regional pool of species. These regional differences in the response of bird assemblages to forest fragmentation are used to discuss the usefulness of large‐scale, biogeographical approaches in the design of conservation guidelines. 相似文献
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Pere Fullana i Palmer Rita Puig Alba Bala Grau Baquero Jordi Riba Marco Raugei 《Journal of Industrial Ecology》2011,15(3):458-475
Life cycle assessment (LCA) is a widely accepted methodology to support decision‐making processes in which one compares alternatives, and that helps prevent shifting of environmental burdens along the value chain or among impact categories. According to regulation in the European Union (EU), the movement of waste needs to be reduced and, if unavoidable, the environmental gain from a specific waste treatment option requiring transport must be larger than the losses arising from transport. The EU explicitly recommends the use of LCA or life cycle thinking for the formulation of new waste management plans. In the last two revisions of the Industrial Waste Management Programme of Catalonia (PROGRIC), the use of a life cycle thinking approach to waste policy was mandated. In this article we explain the process developed to arrive at practical life cycle management (LCM) from what started as an LCA project. LCM principles we have labeled the “3/3” principle or the “good enough is best” principle were found to be essential to obtain simplified models that are easy to understand for legislators and industries, useful in waste management regulation, and, ultimately, feasible. In this article, we present the four models of options for the management of waste solvent to be addressed under Catalan industrial waste management regulation. All involved actors concluded that the models are sufficiently robust, are easy to apply, and accomplish the aim of limiting the transport of waste outside Catalonia, according to the principles of proximity and sufficiency. 相似文献
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Edgardo Salvatierra Mariano J. Alvarez Claudia C. Leishman Elvia Rivas Baquero Viviana P. Lutzky H. Eduardo Chuluyan Osvaldo L. Podhajcer 《PloS one》2015,10(8)
Cell transition to a more aggressive mesenchymal-like phenotype is a hallmark of cancer progression that involves different steps and requires tightly regulated cell plasticity. SPARC (Secreted Protein Acidic and Rich in Cysteine) is a matricellular protein that promotes this transition in various malignant cell types, including melanoma cells. We found that suppression of SPARC expression in human melanoma cells compromised cell migration, adhesion, cytoskeleton structure, and cell size. These changes involved the Akt/mTOR pathway. Re-expression of SPARC or protein addition restored all the cell features. Suppression of SPARC expression was associated with increased Rac1-GTP levels and its membrane localization. Expression of the dominant negative mutant of Rac1 counteracted almost all the changes observed in SPARC-deficient cells. Overall, these data suggest that most of the SPARC-mediated effects occurred mainly through the blockade of Rac1 activity. 相似文献
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Debbie S. Barrington Maria C. Baquero Luisa N. Borrell Natalie D. Crawford 《Obesity (Silver Spring, Md.)》2010,18(2):422-424
This study examines sex and education variations in obesity among US‐ and foreign‐born whites, blacks, and Hispanics utilizing 1997–2005 data from the National Health Interview Survey on 267,585 adults aged ≥18 years. After adjusting for various demographic, health, and socioeconomic factors via logistic regression, foreign‐born black men had the lowest odds for obesity relative to US‐born white men. The largest racial/ethnic disparity in obesity was between US‐born black and white women. High educational attainment diminished the US‐born black–white and Hispanic–white disparities among women, increased these disparities among men, and had minimal effect on foreign‐born Hispanic–white disparities among women and men. Comprehension of these relationships is vital for conducting effective obesity research and interventions within an increasingly diverse United States. 相似文献
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