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51.
SYNOPSIS Cyclic epidermal cellular prohfeiation,with or withoutkeratinization is a vertebrate characteristic Such activityprobably obeys an autonomous rhythm which is legulated throughneuro humoral S)stcms in response to envnonmental (piox imate)stimuliand related to adaptive (ultimate) factors In seeking causeand effect lelationships, however, it becomes apparent thatthe same environmental parameter may be both an ultimate anda pioximate factor, the latter also regulating the rate of lesponseWith regard to molting in homoio'heims, tempeiatuie acts insuch a capacity in many species Peiiodic shedding of the outer epidermis in fish amphibiansand reptiles does not appear to be coirelated with seasonalfactors to the extent that avian and mammalian molts are The evolution of vertebrate molting cycles has amounted to theentraining of inherent epidermal C)cles with seasonal demandsby the organism itself and the environment,these demands actas regulating mechanisms Pieadapted structures such as feathersand hairs function collectively as plumage and pelage in theirvarious roles but separately in their growth and leplacementcycles which, however, are coordinated for maximum functionalefficiency Molting is also synchionized with the seasonal cycleaccording to the availability of energy resources and time tocomplete the essential functions (in addition to molting) Theevolved molting systems as manifested in the gieat variety ofpatterns and types in the vertebrates, may thus be legardedas almost individual responses to selective piessures actingon a umveisil vertebrate chaiacter The basic regulatoiy system involves the neuro hvpophyseal complexwhich contiols target endocrines affecting various functionswhich themselves influence epidermal mitosis and, ultimately,molting 1 he mechanism in its simplest form controls the animalsmetabolism through the thyroid acting independently in a permissivecapacity or synergistically with the adrenal and gonadal hormoneswhich are regulated directly and/or indirectly through negativefeedback 相似文献
52.
Genetics of somatic fusion in a myxomycete: F 2 studies 总被引:1,自引:0,他引:1
H Ling 《Protoplasma》1971,73(3):407-416
53.
Ling Y. Wei 《Bulletin of mathematical biology》1971,33(2):187-194
Based on quantum transitions of membrane dipoles, the four fundamental properties of nerve impulse are derived in this paper:
the all-or-none response, the strength-duration relation, refractoriness and refractory period and frequency modulation. Furthermore,
the theory offers a physical mechanism for nerve excitation similar to a two-level ammonia maser. It also implies non-threshold
excitation at elevated temperatures. The role of trimethylamine ions near the surface of a phospholipid membrane is briefly
discussed to indicate a possible connection between theory and reality. 相似文献
54.
55.
Willy R. G. Baeyens Betty Lin Ling Udo A. Th. Brinkman Stephen G. Schulman 《Luminescence》1989,4(1):484-499
An overview is presented of the physicochemical basis of luminescence, and its application to the detection of chemicals (drugs, biomedically important compounds, environmentally active substances) in liquid chromatographic systems. 相似文献
56.
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58.
P-glycoprotein: multidrug-resistance and a superfamily of membrane-associated transport proteins 总被引:27,自引:0,他引:27
The study of multidrug resistance (MDR) in tumor cell lines has led to the discovery of the plasma membrane P-glycoprotein (Pgp) molecule. This protein functions as an energy-dependent pump for the efflux of diverse anticancer drugs from MDR cells. It now appears that Pgp-mediated MDR tumor cells do occur in human cancers, and that they are likely to play a role in the ultimate response of patients to chemotherapy. Chemosensitizers, compounds able to reverse the MDR phenotype, have been identified and offer the exciting possibility of improving efficacy for some nonresponsive malignancies. Surprisingly, Pgp-like molecules can be found in evolutionarily distant species among both eukaryotes and prokaryotes. As a group, these proteins form a superfamily of ATP-dependent transport proteins. This finding has broad implications and provides new insights into how living organisms use this fundamental transport system to regulate the trafficking of diverse molecules across biological membranes. 相似文献
59.
60.
菘蓝多倍体育种的研究 总被引:39,自引:0,他引:39
本文报道药用植物菘蓝(Isatis indigotica Foft.)同源四倍体的诱发、鉴定、选育的研究。用0.05-0.5%浓度的秋水仙碱水溶液处理萌发的种子,或用0.05-0.3%浓度的此溶液处理幼苗的生长点,均可以获得四倍体植株。最适宜的处理时间为6-12小时。除用直接的细胞学技术鉴定多倍体植株外,一些重要的间接鉴定特征,如叶表皮保卫细胞中叶绿体数,花粉沟数可作为鉴定本种多倍体植株的可靠指标。比较了四倍体植株和二倍体亲本的生物学特性。经过数代选育,获得了性状稳定、繁殖力正常、根与叶中活性成分均有较大幅度提高、生产性能良好的品系。 相似文献