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991.
A 25-year time series for a vendace (Coregonus albula (L.)) population was analysed with mathematical models to reveal the factors that regulate its recruitment. The fitted recruitment model was an age-structured model incorporating the compensatory effects of the spawning population and the abundance of the previous year class. Wind forcing index was also added as an example of an external source of recruitment variability. The auto-correlation analysis revealed a tendency for 2-year generation cyclicity in recruitment. The compensatory effects of both spawning biomass and previous year class abundance on recruitment had to be incorporated into the model to remove cyclicity from residuals. Wind forcing during the larval and early juvenile periods negatively affected recruitment. Re-estimating the parameters of the Cushing recruitment function and the effect of previous year-class from simulated data revealed that the time series structure and measurement errors induce strong biases in parameters exaggerating the density independent population growth rate parameter and the amount of compensation. The negative effect of previous year class was also exaggerated but less severely. Simulations with the artificially perturbed deterministic model skeleton revealed a tendency for cyclicity in recruitment. The model typically generated dampening oscillations, but the dynamics appeared as limit cycles when assuming high mortality, a low level of compensation by spawning biomass and a considerable negative effect of the previous year-class. No single ultimate mechanism for inter-stage effects causing cyclicity can be presently designated despite the rather extensive studies on vendace population dynamics. Several of the suggested mechanisms may be operating in concert. 相似文献
992.
Anne-Mari Mtt Aino Salminen Milla Pietiinen Jaakko Leskel Teemu Palviainen Wolfgang Sattler Juha Sinisalo Veikko Salomaa Jaakko Kaprio Pirkko J Pussinen 《Innate immunity》2021,27(1):3
Our aim was to analyze whether endotoxemia, i.e. translocation of LPS to circulation, is reflected in the serum metabolic profile in a general population and in participants with cardiometabolic disorders. We investigated three Finnish cohorts separately and in a meta-analysis (n = 7178), namely population-based FINRISK97, FinnTwin16 consisting of young adult twins, and Parogene, a random cohort of cardiac patients. Endotoxemia was determined as serum LPS activity and metabolome by an NMR platform. Potential effects of body mass index (BMI), smoking, metabolic syndrome (MetS), and coronary heart disease (CHD) status were considered. Endotoxemia was directly associated with concentrations of VLDL, IDL, LDL, and small HDL lipoproteins, VLDL particle diameter, total fatty acids (FA), glycoprotein acetyls (GlycA), aromatic and branched-chain amino acids, and Glc, and inversely associated with concentration of large HDL, diameters of LDL and HDL, as well as unsaturation degree of FAs. Some of these disadvantageous associations were significantly stronger in smokers and subjects with high BMI, but did not differ between participants with different CHD status. In participants with MetS, however, the associations of endotoxemia with FA parameters and GlycA were particularly strong. The metabolic profile in endotoxemia appears highly adverse, involving several inflammatory characters and risk factors for cardiometabolic disorders. 相似文献
993.
994.
Isabelle Cusin Juha Rouru Franoise Rohner‐Jeanrenaud 《Obesity (Silver Spring, Md.)》2001,9(7):401-406
Objective: The aims of the present study were to determine whether increased body weight resulting from intracerebroventricular (ICV) glucocorticoid (dexamethasone) infusion in normal rats is associated, as in obesity, with changes in glucose metabolism and to investigate whether the parasympathetic nervous system is involved in the glucocorticoid‐induced effects. Research Methods and Procedures: Male Sprague–Dawley rats were infused with ICV dexamethasone (2.5 μg/d) or its vehicle for 2 days during which food intake, body weight, and basal insulinemia were measured. Euglycemic–hyperinsulinemic clamps associated with the labeled 2‐deoxyglucose technique were then performed to determine the total rate of glucose disappearance and the tissue glucose use indices. Similar experiments were carried out in vagotomized rats. Results: Two days of ICV glucocorticoid infusion in normal rats resulted in increases in food intake, body weight, basal insulinemia, and produced decreases in the insulin‐stimulated total rate of glucose disappearance, as well as in glucose use indices of all muscle types studied. None of these alterations was observed when glucocorticoid infusion was carried out in vagotomized rats. Discussion: These data show that central glucocorticoid infusion favors anabolic processes, such as feeding behavior, body weight gain, and insulin output, while promoting muscle insulin resistance. These effects seem to be mediated by an activation of the parasympathetic nervous system, because they all disappear when tested in vagotomized rats. 相似文献
995.
An approach to comprehensive genome and proteome expression analyses in Schwann cells and neurons during peripheral nerve myelin formation 下载免费PDF全文
996.
Metapopulation theory predicts that species richness and total population density of habitat specialists increase with increasing
area and regional connectivity of the habitat. To test these predictions, we examined the relative contributions of habitat
patch area, connectivity of the regional habitat network and local habitat quality to species richness and total density of
butterflies and day-active moths inhabiting semi-natural grasslands. We studied butterflies and moths in 48 replicate landscapes
situated in southwest Finland, including a focal patch and the surrounding network of other semi-natural grasslands within
a radius of 1.5 km from the focal patch. By applying the method of hierarchical partitioning, which can distinguish between
independent and joint contributions of individual explanatory variables, we observed that variables of the local habitat quality
(e.g. mean vegetation height and nectar plant abundance) generally showed the highest independent effect on species richness
and total density of butterflies and moths. Habitat area did not show a significant independent contribution to species richness
and total density of butterflies and moths. The effect of habitat connectivity was observed only for total density of the
declining butterflies and moths. These observations indicate that the local habitat quality is of foremost importance in explaining
variation in species richness and total density of butterflies and moths. In addition, declining butterflies and moths have
larger populations in well-connected networks of semi-natural grasslands. Our results suggest that, while it is crucial to
maintain high-quality habitats by management, with limited resources it would be appropriate to concentrate grassland management
and restoration to areas with well-connected grassland networks in which the declining species currently have their strongest
populations.
Electronic supplementary material The online version of this article (doi:) contains supplementary material, which is available to authorized users. 相似文献
997.
Chromosome numbers from 17 Finnish populations of six taxa in the Carex flava complex were examined. Special attention was given to taxa claimed to be endemic to Fennoscandia. The meiotic counts for C. flava n = 30, C. viridula var. viridula n = 35 and var. pulchella n = 35 are in accordance with previous reports. The counts for C. jemtlandica n = 34, C. bergrothii n = 35, and C. kotilaini n = 34 are new. The hybrid C. flava × kotilaini reveals severely disturbed meiosis with many uni- and multivalents. The results are briefly discussed in relation to morphological data. Carex jemtlandica should evidently be included in C. lepidocarpa. Carex bergrothii and C. kotilaini belong to the polymorphic C. viridula , but the latter probably consitute a specific cytotype. 相似文献
998.
Reproductive timing and individual fitness 总被引:3,自引:0,他引:3
999.
Juha Kere Erkki Savilahti Reijo Norio Xavier Estivill Albert de la Chapelle 《Human genetics》1990,85(4):413-415
Summary The frequency of mutation ΔF508 was determined in all 20 Finnish cystic fibrosis (CF) families with living affected children
(19 with pancreatic insufficiency). ΔF508 was detected in 18 out of 40 CF chromosomes (45%). At least two different mutations
associated with pancreatic insufficiently have occurred in a rare haplotype defined by XV2c, CS.7, KM19 alleles 1 2 2. Geographical
clustering of ΔF508 and other mutations suggested that a founder effect and genetic drift have influenced the frequency of
mutations causing CF in Finland. 相似文献
1000.