全文获取类型
收费全文 | 384篇 |
免费 | 28篇 |
专业分类
412篇 |
出版年
2023年 | 2篇 |
2022年 | 5篇 |
2021年 | 9篇 |
2020年 | 9篇 |
2019年 | 4篇 |
2018年 | 3篇 |
2017年 | 7篇 |
2016年 | 16篇 |
2015年 | 13篇 |
2014年 | 13篇 |
2013年 | 16篇 |
2012年 | 24篇 |
2011年 | 15篇 |
2010年 | 12篇 |
2009年 | 15篇 |
2008年 | 22篇 |
2007年 | 16篇 |
2006年 | 16篇 |
2005年 | 21篇 |
2004年 | 26篇 |
2003年 | 19篇 |
2002年 | 12篇 |
2001年 | 3篇 |
2000年 | 4篇 |
1999年 | 9篇 |
1998年 | 9篇 |
1997年 | 11篇 |
1996年 | 6篇 |
1995年 | 2篇 |
1994年 | 4篇 |
1993年 | 7篇 |
1992年 | 10篇 |
1991年 | 5篇 |
1990年 | 4篇 |
1989年 | 2篇 |
1988年 | 2篇 |
1987年 | 3篇 |
1986年 | 4篇 |
1985年 | 3篇 |
1984年 | 3篇 |
1983年 | 2篇 |
1982年 | 4篇 |
1980年 | 3篇 |
1977年 | 2篇 |
1973年 | 1篇 |
1972年 | 4篇 |
1970年 | 2篇 |
1968年 | 3篇 |
1967年 | 2篇 |
1964年 | 1篇 |
排序方式: 共有412条查询结果,搜索用时 15 毫秒
41.
Simões Nadson R. Braghin Louizi S. M. Duré Gustavo A. V. Santos Josiane S. Sonoda Sérgio L. Bonecker Cláudia C. 《Hydrobiologia》2020,847(18):3845-3856
Hydrobiologia - Disturbances caused by both natural and anthropogenic forces can drive changes in alpha and beta taxonomic diversity and be accompanied by losses or gains in freshwater ecosystem... 相似文献
42.
Summary A histological, histochemical and ultrastrucutral study of the pars intercerebralis (PI) has been made in Locusta migratoria.
The acellular neural lamella is made up of an elastic tissue and collagen fibrils. The cells of the perilemma contain numerous lysosome structures and lipid granules.Three different types of neurosecretory cells (NSC A, B and C) have been distinguished in the PI associated with giant neurons.The cells termed A and B seem not to have an activity cycle during the two last larval instars. At the moment of sexual maturity the NSC A show an important accumulation of neurosecretory material and their number increases at the expense of the NSC B. The NSC A, which are characterized by a highly developped endoplasmic reticulum, contain numerous secretory granules which appear to be individualized in the Golgi complex in three different ways. The NSC B, with a reduced endoplasmic reticulum and an almost quiescent Golgi complex, contain abundant lysosome structures and more seldom some neurosecretory granules. In fact, the study of the fine structure shows different intermediate types, linking in a continuous way typical A cells and typical B cells. NSC A and NSC B might correspond to two opposed stages of secretory activity of one single cell type: the A cell representing the activity stage and the B cell the quiescent stage.NSC C show an accumulation of their neurosecretory products in relation to metamorphosis and sexual maturity. Ultrastructural evidence confirms their neurosecretory activity.A mode of regulating neurosecretion in NSC A and B by internal catabolism of the secretion and formation of lysosome like structures is discussed in the present paper.The giant neurons, which are surrounded by a glial envelope (trophospongium), contain several dense granules originated from Golgi complex. 相似文献
43.
44.
Rieusset J Seydoux J Anghel SI Escher P Michalik L Soon Tan N Metzger D Chambon P Wahli W Desvergne B 《Molecular endocrinology (Baltimore, Md.)》2004,18(10):2363-2377
The peroxisome proliferator-activated receptor gamma (PPARgamma) plays a major role in fat tissue development and physiology. Mutations in the gene encoding this receptor have been associated to disorders in lipid metabolism. A thorough investigation of mice in which one PPARgamma allele has been mutated reveals that male PPARgamma heterozygous (PPARgamma +/-) mice exhibit a reduced body size associated with decreased body weight, reflecting lean mass reduction. This phenotype is reproduced when treating the mice with a PPARgamma- specific antagonist. Monosodium glutamate treatment, which induces weight gain and alters body growth in wild-type mice, further aggravates the growth defect of PPARgamma +/- mice. The levels of circulating GH and that of its downstream effector, IGF-I, are not altered in mutant mice. However, the IGF-I mRNA level is decreased in white adipose tissue (WAT) of PPARgamma +/- mice and is not changed by acute administration of recombinant human GH, suggesting an altered GH action in the mutant animals. Importantly, expression of the gene encoding the suppressor of cytokine signaling-2, which is an essential negative regulator of GH signaling, is strongly increased in the WAT of PPARgamma +/- mice. Although the relationship between the altered GH signaling in WAT and reduced body size remains unclear, our results suggest a novel role of PPARgamma in GH signaling, which might contribute to the metabolic disorder affecting insulin signaling in PPARgamma mutant mice. 相似文献
45.
Uva P Clément JL Austin JW Aubert J Zaffagnini V Quintana A Bagnères AG 《Molecular phylogenetics and evolution》2004,30(2):344-353
The Holoarctic termite genus Reticulitermes is widely distributed in Europe. A new Reticulitermes species, R. sp. nov, was recently found in France and Italy. Its phylogenetic position was investigated using a 743-bp fragment of mitochondrial 16S rRNA-ND1 genes and 382-bp of the nuclear ITS2 region. Phylogenies for these sequences were estimated by neighbor-joining, maximum-parsimony and maximum-likelihood analysis. The results strongly supported a relationship between R. sp. nov. and the termite species from the eastern Mediterranean area including Reticulitermes balkanensis from the Balkans, Reticulitermes lucifugus from Turkey and Reticulitermes clypeatus from Israel. The hypothesis of a relationship between R. sp. nov. and the Japanese Reticulitermes speratus was rejected by parametric bootstrap. The current distribution of R. sp. nov. could be linked to postglacial colonization routes between Balkan refuge and northern regions. 相似文献
46.
47.
48.
49.
50.