全文获取类型
收费全文 | 88篇 |
免费 | 5篇 |
专业分类
93篇 |
出版年
2022年 | 1篇 |
2021年 | 2篇 |
2020年 | 1篇 |
2019年 | 1篇 |
2017年 | 1篇 |
2016年 | 1篇 |
2015年 | 4篇 |
2014年 | 3篇 |
2013年 | 4篇 |
2012年 | 10篇 |
2011年 | 10篇 |
2010年 | 6篇 |
2009年 | 4篇 |
2008年 | 4篇 |
2007年 | 4篇 |
2006年 | 7篇 |
2005年 | 4篇 |
2004年 | 7篇 |
2003年 | 5篇 |
2002年 | 1篇 |
2001年 | 1篇 |
2000年 | 1篇 |
1997年 | 2篇 |
1996年 | 3篇 |
1993年 | 1篇 |
1991年 | 1篇 |
1990年 | 1篇 |
1989年 | 1篇 |
1985年 | 1篇 |
1976年 | 1篇 |
排序方式: 共有93条查询结果,搜索用时 0 毫秒
51.
Jorunn M. Andersen Hilde Herning Elin L. Aschim J?ran Hjelmes?th Tom Mala Hans Ivar Hanevik Mona Bungum Trine B Haugen Oliwia Witczak 《PloS one》2015,10(6)
There is still controversy as to how body mass index (BMI) affects male reproduction. We investigated how BMI is associated with semen quality and reproductive hormones in 166 men, including 38 severely obese men. Standard semen analysis and sperm DNA integrity analysis were performed, and blood samples were analysed for reproductive hormones. Adjusted for age and time of abstinence, BMI was negatively associated with sperm concentration (B = -0.088, P = 0.009), total sperm count (B = -0.223, P = 0.001), progressive sperm motility (B = -0.675, P = 0.007), normal sperm morphology (B = -0.078, P = 0.001), and percentage of vital spermatozoa (B = -0.006, P = 0.027). A negative relationship was observed between BMI and total testosterone (B = -0.378, P < 0.001), sex hormone binding globulin (B = -0.572, P < 0.001), inhibin B (B = -3.120, P < 0.001) and anti-Müllerian hormone (AMH) (B = -0.009, P < 0.001). Our findings suggest that high BMI is negatively associated with semen characteristics and serum levels of AMH. 相似文献
52.
53.
Daniel J. Leybourne Katharine F. Preedy Tracy A. Valentine Jorunn I. B. Bos Alison J. Karley 《Ecology and evolution》2021,11(17):11915
- Aphids are abundant in natural and managed vegetation, supporting a diverse community of organisms and causing damage to agricultural crops. Due to a changing climate, periods of drought are anticipated to increase, and the potential consequences of this for aphid–plant interactions are unclear.
- Using a meta‐analysis and synthesis approach, we aimed to advance understanding of how increased drought incidence will affect this ecologically and economically important insect group and to characterize any potential underlying mechanisms. We used qualitative and quantitative synthesis techniques to determine whether drought stress has a negative, positive, or null effect on aphid fitness and examined these effects in relation to (a) aphid biology, (b) geographical region, and (c) host plant biology.
- Across all studies, aphid fitness is typically reduced under drought. Subgroup analysis detected no difference in relation to aphid biology, geographical region, or the aphid–plant combination, indicating the negative effect of drought on aphids is potentially universal. Furthermore, drought stress had a negative impact on plant vigor and increased plant concentrations of defensive chemicals, suggesting the observed response of aphids is associated with reduced plant vigor and increased chemical defense in drought‐stressed plants.
- We propose a conceptual model to predict drought effects on aphid fitness in relation to plant vigor and defense to stimulate further research.
54.
Dieleman Jorunn Cocquyt Christine Nyingi Wanja Dorothy Verschuren Dirk 《Hydrobiologia》2021,848(16):3763-3777
Hydrobiologia - Oreochromis cf. korogwe and Coptodon rendalli, two tilapiine fishes introduced to Lake Chala (Kenya/Tanzania) ~?40 years ago, may negatively affect the endemic Chala... 相似文献
55.
The Holocene lake history, vegetation history and climate history of Brurskardstjørni, an alpine lake in the Jotunheimen Mountains of south-central Norway, are reconstructed. The reconstructions are based on fossil pollen, plant macrofossils, diatoms, chironomids and sediment characteristics. Subsequent to deglaciation, the lake was formed at about 11,000 cal years BP. A diverse chironomid assemblage quickly colonised the lake, whereas the first diatoms were found about 400 years later. At that time, the lake water was turbid with a high pH. The surrounding soils were immature and unstable and dominated by open pioneer vegetation. Compared to the present, summer temperatures were warmer and there was less winter precipitation. From about 10,000 cal years BP, local organic production increased rapidly and from about 9,500 cal years BP a few macrofossils and a high pollen influx of birch suggest that the tree-line was close to the lake. Pine most likely reached its highest tree-line altitude around 9,000 cal years BP and has receded since that time. From about 5,000 cal years BP, the total amount of trees and shrubs decreased and the landscape became more open, probably due to decreasing temperatures and increasing effective moisture lowering the birch tree-line. Coinciding with a cooling during the last 3,000 years, lake-water pH decreased. There is large incongruence between the Holocene July temperatures inferred from pollen and chironomids. The biological proxies responded to a combined effect of environmental change and biotic interactions. This response is interpreted with reference to taxon–environment relationships in the modern calibration data sets and with reference to the latent structure and ecological demands of the fossil assemblages. 相似文献
56.
Light and temperature sensing and signaling in induction of bud dormancy in woody plants 总被引:2,自引:0,他引:2
Jorunn E. Olsen 《Plant molecular biology》2010,73(1-2):37-47
57.
Kirkeleit J Riise T Bråtveit M Pekari K Mikkola J Moen BE 《Chemico-biological interactions》2006,164(1-2):60-67
We investigated the association between the individual concentrations of benzene in the breathing zone and the concentrations of benzene in the blood and urine among workers maintaining crude oil cargo tanks. Benzene exposure was measured during three consecutive 12h work days among 13 tank workers and 9 unexposed referents (catering section). Blood and urine samples were collected pre-shift on the first day, post-shift on the third day, and pre-next shift on the following morning. The workers used half-mask air-purifying respirators, but not all workers used these systematically. The individual geometric mean benzene exposure in the breathing zone of tank workers over 3 days was 0.15 ppm (range 0.01-0.62 ppm). The tank workers' post-shift geometric mean benzene concentrations were 12.3 nmol/l in blood and 27.0 nmol/l in urine versus 0.7 nmol/l for both blood and urine among the referents. Benzene in the work atmosphere was highly correlated with the internal concentration of benzene both in post-shift blood (r=0.87, P<0.001) and post-shift urine (r=0.90, P<0.001), indicating that the varying use of respirators did not explain much of the variability in absorbed benzene. The results showed that, despite low benzene exposure in this work atmosphere and the use of personal protective equipment to a varying degree, the tank workers had a significant uptake of benzene that correlated highly with benzene exposure. The internal concentration of benzene was higher than expected considering the measured individual benzene exposure, probably due to an extended work schedule of 12h and physical strain during tank work. Control measures should be improved for processes, which impose a potential for increased absorption of benzene upon the workers. 相似文献
58.
59.
60.
Jin X Stamnaes J Klöck C DiRaimondo TR Sollid LM Khosla C 《The Journal of biological chemistry》2011,286(43):37866-37873
The mechanism of activation of transglutaminase 2 (TG2) in the extracellular matrix remains a fundamental mystery in our understanding of the biology of this multifunctional mammalian enzyme. Earlier investigations have highlighted the role of a disulfide bond formed by vicinal Cys residues in maintaining calcium-bound TG2 in an inactive state. Here, we have shown that the redox potential of this disulfide bond is approximately -190 mV, a high value for a disulfide bond in proteins. Consistent with this observation, TG2 activity in a freshly wounded fibroblast culture depends upon the redox potential of the environment. We sought to identify a physiological mechanism for the activation of oxidized TG2. With a k(cat)/K(m) of 1.6 μm(-1) min(-1), human thioredoxin (Trx) was a highly specific activator of oxidized human TG2. Trx-mediated activation of TG2 was blocked by PX-12, a small molecule Trx inhibitor that is undergoing clinical trials as a cancer chemotherapeutic agent. In a mixed culture containing fibroblasts and monocytic cells, interferon-γ stimulated Trx release from monocytes, which in turn activated TG2 around the fibroblasts. Recombinant human Trx could also activate extracellular TG2 in cryosections of human and mouse small intestinal biopsies. In addition to explaining how TG2 can be activated by dietary gluten in the small intestinal mucosa of celiac sprue patients, our findings reveal a new strategy for inhibiting the undesirable consequences of TG2 activity in this widespread, lifelong disease. 相似文献