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901.
Summary BENN, G.A. &; KEMP, A.C. 1995. Diet, home range, hunting and reproductive behaviour of a pair of Dickinson's Kestrel Falco dickinsoni in the Kruger National Park, South Africa. Ostrich 66: 81–91. During July-December 1992, the diet, home range, hunting and reproductive behaviour of a pair of Dickinson's Kestrel Falco dickinsoni was recorded in the Kruger National Park, South Africa. Numerically, for both sexes combined, invertebrates formed the majority (56%) of the diet, while separately the female caught 75% and the male 49% invertebrate prey. During courtship and incubation the male supplied the female with primarily vertebrate prey and both provisioned mainly vertebrates to the nestlings (male = 80%; female = 57%). The non-breeding home range of the female was 27.8 km2, and the breeding home range of the male was 26.3 km2. Both utilised their home ranges differentially, the area within a 2 km radius of the nest (12.6 km2) being used proportionally more than the remaining area. The home range of the female was compared to that of other Falco spp. and was larger than would be expected based on body weight. Perch-hunting was the only technique utilised by both sexes, with 79–80% of observed strike attempts from dead trees. During the day, the 9.emale spent 87% and the male 77% of the time perch-hunting, with respective hunting success rates of 69% and 58%. During courtship, the female spent much of her time (94%) close to the nest, where the male supplied her with prey. During incubation, the male spent 95% of his time within 2 km of the nest tree, where he hunted to supply the female with prey at a rate of 0.3 items.hr?1 and assisted in nest defence. On occasion the male entered the nest to relieve the female, and remained in the cavity on average for 134 min (n = 5). As the young got older, the female spent less time at the nest and provisioned more items to the nestlings. Overall, there was an increase in the rate of prey provisioning to the nestlings from 0.45 items.hr?1 (10 days old) to 0.85 items.hr?1 (21 days old). The male initially passed prey to the female but provisioned directly to older nestlings. 相似文献
902.
903.
Graham J. Kemp Hamed I. Khouja Abdulla Ahmado R. Graham G. Russell Alan Bevington 《Cell biochemistry and function》1993,11(1):13-23
Osteoblast-like cells possess Na-dependent transporters which accumulate orthophosphate (Pi) from the extracellular medium. This may be important in bone formation. Here we describe parallel measurements of Pi uptake and cellular [Pi] in such cells from the rat (UMR 106–01 and UMR 106–06) and human (OB), and in non-osteoblastic human fibroblasts (Detroit 532 (DET)). In UMR 106–01, cellular [Pi] was weakly dependent on extracellular [Pi] and higher than expected from passive transport alone. [32Pi]-uptake was inhibited by Na deprivation, but paradoxically increased on K deprivation. With Na, 87 per cent of cellular 32P was found in organic phosphorus pools after only 5 min. Na deprivation also decreased cellular [Pi], in both UMR 106–01 and DET, but the decrease was smaller than that in [32Pi]-uptake. Ouabain decreased [32Pi]-uptake and cellular [Pi] in DET, but not in UMR 106–01. Regulation of cellular [Pi] is therefore at least partly dependent on Na/Pi co-transport, but this does not seem to be an exclusive property of osteoblasts. 相似文献
904.
Gaurav Dwivedi Margaret A. Gran Pritha Bagchi Melissa L. Kemp 《PLoS computational biology》2015,11(11)
Quantifying the magnitude and dynamics of protein oxidation during cell signaling is technically challenging. Computational modeling provides tractable, quantitative methods to test hypotheses of redox mechanisms that may be simultaneously operative during signal transduction. The interleukin-4 (IL-4) pathway, which has previously been reported to induce reactive oxygen species and oxidation of PTP1B, may be controlled by several other putative mechanisms of redox regulation; widespread proteomic thiol oxidation observed via 2D redox differential gel electrophoresis upon IL-4 treatment suggests more than one redox-sensitive protein implicated in this pathway. Through computational modeling and a model selection strategy that relied on characteristic STAT6 phosphorylation dynamics of IL-4 signaling, we identified reversible protein tyrosine phosphatase (PTP) oxidation as the primary redox regulatory mechanism in the pathway. A systems-level model of IL-4 signaling was developed that integrates synchronous pan-PTP oxidation with ROS-independent mechanisms. The model quantitatively predicts the dynamics of IL-4 signaling over a broad range of new redox conditions, offers novel hypotheses about regulation of JAK/STAT signaling, and provides a framework for interrogating putative mechanisms involving receptor-initiated oxidation. 相似文献
905.
Ryszard Koczura Beata Przyszlakowska Joanna Mokracka Adam Kaznowski 《Current microbiology》2014,69(3):258-262
Sixty-three clinical isolates of Acinetobacter calcoaceticus–baumannii complex were analyzed for the presence of integrons and antimicrobial resistance. Class 1 integrons were detected in 40 (63.5 %) isolates. None of them had class 2 or class 3 integrons. The majority of the integrons contained aacC1–orfA–orfB–aadA1 gene cassette array. The presence of integrons was associated with the increased frequency of resistance to 12 of 15 antimicrobials tested, multi-drug resistance phenotype, and the overall resistance ranges of the strains. 相似文献
906.
907.
Isomerization of linolenic acid by rumen micro-organisms. 总被引:6,自引:6,他引:0
908.
Joanna Papierska Bartłomiej S. Witkowski Anastasiya Derkachova Krzysztof P. Korona Johannes Binder Krzysztof Gałkowski Łukasz Wachnicki Marek Godlewski Tomasz Dietl Jan Suffczyński 《Plasmonics (Norwell, Mass.)》2013,8(2):913-919
A simple fabrication method of silver (Ag) nanoislands on ZnO films is presented. Continuous wave and time-resolved photoluminescence and transmission are employed to investigate modifications of visible and UV emissions of ZnO brought about by coupling to localized surface plasmons residing on Ag nanoislands. The size of the nanoislands, determining their absorption and scattering efficiencies, is found to be an important factor governing plasmonic modification of optical response of ZnO films. The presence of the Ag nanoislands of appropriate dimensions causes a strong (threefold) increase in emission intensity and up to 1.5 times faster recombination. The experimental results are successfully described by model calculations within the Mie theory. 相似文献
909.
910.
Monika Marcinkowska Magdalena Kotańska Agnieszka Zagórska Joanna Śniecikowska Monika Kubacka Agata Siwek 《Journal of enzyme inhibition and medicinal chemistry》2018,33(1):536-545
Despite the substantial clinical success of aspirin and clopidogrel in secondary prevention of ischemic stroke, up to 40% of patients remain resistant to the available antiplatelet treatment. Therefore, there is an urgent clinical need to develop novel antiplatelet agents with a novel mechanism of action. Recent studies revealed that potent alpha 2B-adrenergic receptor (alpha 2B-ARs) antagonists could constitute alternative antiplatelet therapy. We have synthesized a series of N-arylpiperazine derivatives of 4,4-dimethylisoquinoline-1,3(2H,4H)-dione as potential alpha 2B receptor antagonists. The most potent compound 3, effectively inhibited the platelet-aggregation induced both by collagen and ADP/adrenaline with IC50 of 26.9?μM and 20.5?μM respectively. Our study confirmed that the alpha 2B-AR antagonists remain an interesting target for the development of novel antiplatelet agents with an alternative mechanism of action. 相似文献