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991.
Background
Although capable to evolve, viruses are generally considered non-living entities because they are acellular and devoid of metabolism. However, the recent publication of the genome sequence of the Mimivirus, a giant virus that parasitises amoebas, strengthened the idea that viruses should be included in the tree of life. In fact, the first phylogenetic analyses of a few Mimivirus genes that are also present in cellular lineages suggested that it could define an independent branch in the tree of life in addition to the three domains, Bacteria, Archaea and Eucarya. 相似文献992.
Background
Overlapped genes originate by a) loss of a stop codon among contiguous genes coded in different frames; b) shift to an upstream initiation codon of one of the contiguous genes; or c) by overprinting, whereby a novel open reading frame originates through point mutation inside an existing gene. Although overlapped genes are common in viruses, it is not clear whether overprinting has led to new genes in prokaryotes. 相似文献993.
Katelin D. Pearson 《Biodiversity and Conservation》2018,27(11):3007-3018
Distributions of taxa across time and space are central to understanding biodiversity and biotic change, yet currently available occurrence data, drawn from biodiversity specimen records and observational datasets, are often insufficient to answer many driving questions. Records of “associated taxa,” taxa co-occurring with a specimen at the time and place of collection, have the potential to fill data gaps and expand the spatiotemporal scope of current occurrence records. I developed a method to extract associated taxon records from 84,328 digitized specimen records and examined the potential of these data to improve the quantity and quality of existing species occurrence data. Adding associated taxon records increased the size of the test dataset by 18.5%, spanned multiple decades (1937–2016), and potentially extended the known range of 217 taxa in Florida and up to 1500 taxa in the United States, demonstrating the capacity of these records to deepen our understanding of changes in the distributions of taxa on Earth. These results suggest that increased attention to documenting associated taxa could be a promising way to maximize the impact of every collecting event. 相似文献
994.
Roles of Peroxisome Proliferator-Activated Receptor Gamma on Brain and Peripheral Inflammation 总被引:1,自引:0,他引:1
Sonia Villapol 《Cellular and molecular neurobiology》2018,38(1):121-132
Peroxisome proliferator-activated receptor gamma (PPARγ) has been implicated in the pathology of numerous diseases involving diabetes, stroke, cancer, or obesity. It is expressed in diverse cell types, including vessels, immune and glial cells, and neurons. PPARγ plays crucial roles in the regulation of cellular differentiation, lipid metabolism, or glucose homeostasis. PPARγ ligands also exert effects on attenuating degenerative processes in the brain, as well as in peripheral systems, and it has been associated with the control of anti-inflammatory mechanisms, oxidative stress, neuronal death, neurogenesis, differentiation, and angiogenesis. This review will highlight key advances in the understanding of the PPARγ-related mechanisms responsible for neuroprotection after brain injuries, both ischemia and traumatic brain injury, and it will also cover the natural and synthetic agonist for PPARγ, angiotensin receptor blockers, and PPARγ antagonists, used in experimental and clinical research. A better understanding of the pleiotropic mechanisms and applications of these drugs to improve the recovery and to repair the acute and chronic induced neuroinflammation after brain injuries will pave the way for more effective therapeutic strategies after brain deficits. 相似文献
995.
By using hematoxylin staining, peculiarities of chromatin of diapausing silkworm embryos were studied in normal and parthenogenetic development. A direct correlation was revealed between the number of interphase chromatin grains and the number of chromosomes in the nucleus; polyploidization of cells in embryo was studied at the stage of diapause. The polyploidization in parthenogenesis is not restricted to endomitotic chromosome set doubling, as it includes 6n-nuclei. To explain the more diverse spectrum of polyploid cells in parthenogenesis (as compared with the norm), it is necessary to take into account fusion of cleavage nuclei, which is realized by the cytoplasmic mechanism of karyogamy in the absence of fertilization. On squash preparations, for the first time, we identified primordial germ cells of the diapausing embryo, which are characterized by less compact chromatin, especially in the zygotic variant of development; by larger nuclei and cytoplasm; and by an irregular number and size of nucleoli. Estimation of ploidy of the primary germ cells in parthenogenesis by counting “loose” chromatin grains in diapause is possible and indicates polyploidization in the primordial germ cells. This explains an inevitable admixture of tetraploid eggs in the grain of diploid parthenoclones and its absence in normal development. The cytological method used has revealed a spiral arrangement of chromatin grains on the internal nuclear surface at different ploidy levels. 相似文献
996.
997.
Michael C. F. Proctor 《Plant Growth Regulation》2010,62(3):233-240
Desiccation-tolerant plants vary greatly in the rate of recovery of chlorophyll-fluorescence parameters on re-wetting. This
paper seeks general curves that will adequately describe the course of recovery, and quantify the variations in rate within
and between species. Recovery of F
v
/F
m is closely fitted in many species by a logistic curve, starting from zero, on a logarithmic time-scale (seconds to days).
Such curves have three parameters, an asymptote at maximum F
v
/F
m, a half-recovery time (T
0.5), and a slope constant (S). If F
v
/F
m in dry material differs substantially from zero, four-parameter logistic curves can give a better fit. In either case, T
0.5 and S show wide ecologically-significant variation. Some species show anomalously high values of F
v
/F
m in the early minutes of recovery, alongside low absolute values of F
m; these invite further investigation. Logistic curves give good fits to the recovery in light of Φ
PSII, q
P, and photosynthetic CO2 fixation. The results provide the means to quantify ‘high-inertia’ versus ‘low-inertia’ strategies of desiccation tolerance,
and to explore the factors influencing recovery time and rate, and the reasons for some discrepancies from the common course
of recovery. There is substantial overlap in all parameters between the bryophytes and pteridophytes studied. 相似文献
998.
Dean C Adams 《BMC evolutionary biology》2010,10(1):72
Background
Parallel evolution can occur when common environmental factors exert similar selective forces on morphological variation in populations in different geographic localities. Competition can also generate morphological shifts, and if competing species co-occur in multiple geographic regions, then repeated instances of competitively-driven morphological divergence (character displacement) can occur. Despite the importance of character displacement for inferring the role of selection in morphological evolution however, replicated instances of sympatric morphological divergence are understudied. 相似文献999.
The development of policy approaches for reducing nitrogen pollution to coastal waters of the USA 总被引:1,自引:0,他引:1
Robert W. Howarth 《中国科学C辑(英文版)》2005,48(2):791-806
Two-thirds of the coastal rivers and bays in the United States are degraded from nutrient pollution, and nitrogen inputs these waters continue to increase. The nitrogen comes from a variety of sources, including runoff from agricultural fields, concentrated animal feeding operations, atmospheric deposition from fossil fuel combustion, and sewage and septic wastes. Technical solutions for nitrogen pollution exist at reasonable cost. That most of these solutions have not yet been implemented to any significant extent across the United States suggests that new policy approaches are necessary. The best solution may involve a combination of voluntary and mandatory approaches, applying different approaches to different sources of nitrogen pollution. A watershed-based approach that relies heavily on voluntary mechanisms (such as crop-yield insurance to reduce over-fertilization) is likely to be the most effective for some sources of nitrogen (such as runoff from agricultural fields), while a uniform national regulatory approach may be better for others (such as NOx emissions from fossil fuel combustion). Implementation of management strategies should be carefully coupled to monitoring programs to assess the effectiveness of these strategies. While both nitrogen and phosphorus are important to control, the focus should be on nitrogen management, in part because nitrogen is more generally the causal agent of coastal eutrophication. Also, while nitrogen-control practices tend to also reduce phosphorus pollution, phosphorus-control practices often have little effect on nitrogen. Although current scientific and technical knowledge is sufficient to begin to make substantial progress toward solving coastal nitrogen pollution, progress will be made more quickly and more cost effectively with increased investment in appropriate scientific research. 相似文献
1000.