全文获取类型
收费全文 | 2792篇 |
免费 | 168篇 |
国内免费 | 2篇 |
专业分类
2962篇 |
出版年
2023年 | 21篇 |
2022年 | 26篇 |
2021年 | 41篇 |
2020年 | 38篇 |
2019年 | 31篇 |
2018年 | 118篇 |
2017年 | 98篇 |
2016年 | 126篇 |
2015年 | 89篇 |
2014年 | 117篇 |
2013年 | 195篇 |
2012年 | 179篇 |
2011年 | 209篇 |
2010年 | 145篇 |
2009年 | 102篇 |
2008年 | 61篇 |
2007年 | 60篇 |
2006年 | 68篇 |
2005年 | 24篇 |
2004年 | 24篇 |
2003年 | 23篇 |
2002年 | 24篇 |
2001年 | 35篇 |
2000年 | 31篇 |
1999年 | 28篇 |
1997年 | 33篇 |
1996年 | 36篇 |
1995年 | 30篇 |
1994年 | 36篇 |
1993年 | 23篇 |
1992年 | 34篇 |
1991年 | 29篇 |
1990年 | 22篇 |
1989年 | 28篇 |
1988年 | 21篇 |
1986年 | 30篇 |
1985年 | 28篇 |
1984年 | 37篇 |
1983年 | 31篇 |
1982年 | 25篇 |
1981年 | 28篇 |
1980年 | 22篇 |
1979年 | 31篇 |
1978年 | 25篇 |
1976年 | 21篇 |
1975年 | 21篇 |
1973年 | 27篇 |
1969年 | 21篇 |
1966年 | 22篇 |
1958年 | 20篇 |
排序方式: 共有2962条查询结果,搜索用时 15 毫秒
101.
102.
The glucocorticoid receptor (GR) is an important player in the life of a cell. This is underlined by a cohort of protein and nucleic acid structures interacting with the GR. Among many issues surrounding GR activity that are under active investigation, the role of microtubules (MTs) is still unclear. This article aims to evaluate the ayes and noes in favor of microtubule importance and then form a hypothesis on their function in GR activity. 相似文献
103.
Vorlíčková M Kejnovská I Sagi J Renčiuk D Bednářová K Motlová J Kypr J 《Methods (San Diego, Calif.)》2012,57(1):64-75
Circular dichroism (CD) is remarkably sensitive to the conformational states of nucleic acids; therefore, CD spectroscopy has been used to study most features of DNA and RNA structures. Quadruplexes are among the significant noncanonical nucleic acids architectures that have received special attentions recently. This article presents examples on the contribution of CD spectroscopy to our knowledge of quadruplex structures and their polymorphism. The examples were selected to demonstrate the potential of this simple method in the quadruplex field. As CD spectroscopy detects only the global feature of a macromolecule, it should preferably be used in combination with other techniques. On the other hand, CD spectroscopy, often as a pioneering approach, can reveal the formation of particular structural arrangements, to search for the conditions stabilizing the structures, to follow the transitions between various structural states, to explore kinetics of their appearance, to determine thermodynamic parameters and also detect formation of higher order structures. This article aims to show that CD spectroscopy is an important complementary technique to NMR spectroscopy and X-ray diffraction in quadruplex studies. 相似文献
104.
105.
106.
Ondřej Korábek Lucie Juřičková Adam Petrusek 《Journal of Zoological Systematics and Evolutionary Research》2020,58(4):944-956
Exact locations of glacial refugia are relevant for the study of contemporary biodiversity, not only as places less disturbed during the climatic changes but also as sources of rapid expansion of the biota after the Last Glacial cycle. If continuously inhabited over several of the Quaternary glacial cycles, the refugia are readily identifiable by the accumulated genetic diversity. However, the sources of the Holocene range expansion, particularly important for the emergence of present-day bio- and phylogeographic patterns and for realistic estimation of species’ expansion rates, might have been located at the fringes of the glacial species ranges and lack unique lineages. This problem is pertinent when the variation is explored at slowly evolving genetic markers. We suggest that the location of such source refugia may be approximated by reconstructing the geographic location as a continuous trait evolving along the branches of a phylogenetic tree. We applied this approach, using the BEAST software, on two large southeast European land snail species: Caucasotachea vindobonensis and Helix thessalica. We found evidence for C. vindobonensis refugia in the western Balkans; notable is an apparently old refugium in Bosnia and Herzegovina. The plausible sources of the species’ Holocene range expansion, however, were located around the south-western end of the Carpathians. Although the source areas were likely similar in H. thessalica, some expansion sources suggested by the analyses (e.g., Podolia, Ukraine) appeared implausible and driven by sampling clustered in that area. The applied approach allows for additional exploitation of the mitochondrial data gathered during the past two decades of animal phylogeography studies. 相似文献
107.
Magdalena Gajdoov Oldich Sychra Jakub Kreisinger Ondej Sedl
ek Eric Djomo Nana Tom Albrecht Pavel Munclinger 《Ecology and evolution》2020,10(13):6512-6524
Coevolutionary processes that drive the patterns of host–parasite associations can be deduced through congruence analysis of their phylogenies. Feather lice and their avian hosts have previously been used as typical model systems for congruence analysis; however, such analyses are strongly biased toward nonpasserine hosts in the temperate zone. Further, in the Afrotropical region especially, cospeciation studies of lice and birds are entirely missing. This work supplements knowledge of host–parasite associations in lice using cospeciation analysis of feather lice (genus Myrsidea and the Brueelia complex) and their avian hosts in the tropical rainforests of Cameroon. Our analysis revealed a limited number of cospeciation events in both parasite groups. The parasite–host associations in both louse groups were predominantly shaped by host switching. Despite a general dissimilarity in phylogeny for the parasites and hosts, we found significant congruence in host–parasite distance matrices, mainly driven by associations between Brueelia lice and passerine species of the Waxbill (Estrildidae) family, and Myrsidea lice and their Bulbul (Pycnonotidae) host species. As such, our study supports the importance of complex biotic interactions in tropical environments. 相似文献
108.
Francová Kateřina Šumberová Kateřina Kučerová Andrea Šorf Michal Grill Stanislav Exler Norbert Vrba Jaroslav 《Wetlands Ecology and Management》2021,29(1):93-110
Wetlands Ecology and Management - Plants play an important role in fishpond littorals, but little is known about factors influencing their presence and growth patterns. We surveyed vegetation of... 相似文献
109.
Ptáková Michaela Pokorný Petr Šída Petr Novák Jan Horáček Ivan Juřičková Lucie Meduna Petr Bezděk Aleš Myšková Eva Walls Matthew Poschlod Peter 《Vegetation History and Archaeobotany》2021,30(2):269-286
Vegetation History and Archaeobotany - In a continuous, perfectly stratified sedimentary sequence which was discovered under a large sandstone overhang in northern Bohemia, Czech Republic, we... 相似文献
110.
Lukáš Pola Vojtěch Hejduk Aleš Zíka Tomáš Winkelhöfer Jiří Šmíd Salvador Carranza Mohammed Shobrak Mohammad Abu Baker Zuhair Sami Amr 《Saudi Journal of Biological Sciences》2021,28(6):3511-3516
Geckos of the genus Trigonodactylus are widely distributed in the sand deserts of the Arabian Peninsula. Three species of this genus are currently recognized, with a fourth one, Stenodactylus pulcher, which placement within Trigonodactylus has been tentatively suggested, but not yet confirmed. We present a phylogenetic analysis of the genus Trigonodactylus with new specimens collected in central Saudi Arabia and southern Jordan. New genetic data has been generated from three mitochondrial markers to investigate the phylogenetic relationships of all species of the genus and to assess the putative generic assignment of S. pulcher. Our results confirm that S. pulcher indeed belongs within Trigonodactylus, branching as a sister lineage to all other species of the genus. The new samples cluster within Trigonodactylus arabicus, thus confirming the genetic homogeneity of the species across its large and seemingly inhospitable range. The new specimen collected in southern Jordan represents the first record for the country and a considerable range extension to the northwest from all previously reported localities. Our findings and discovery of a new species for Jordan highlight the need of more field surveys to be carried out in the underexplored parts of Jordan and northern Saudi Arabia, as these places still hold a potential for new discoveries and are crucial for understating the biogeography of the Arabian herpetofauna. 相似文献