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151.
Eco‐evolutionary dynamics have been shown to be important for understanding population and community stability and their adaptive potential. However, coevolution in the framework of eco‐evolutionary theory has not been addressed directly. Combining experiments with an algal host and its viral parasite, and mathematical model analyses we show eco‐evolutionary dynamics in antagonistic coevolving populations. The interaction between antagonists initially resulted in arms race dynamics (ARD) with selective sweeps, causing oscillating host–virus population dynamics. However, ARD ended and populations stabilised after the evolution of a general resistant host, whereas a trade‐off between host resistance and growth then maintained host diversity over time (trade‐off driven dynamics). Most importantly, our study shows that the interaction between ecology and evolution had important consequences for the predictability of the mode and tempo of adaptive change and for the stability and adaptive potential of populations. 相似文献
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153.
Manuel J. Steinbauer Richard Field John‐Arvid Grytnes Panayiotis Trigas Claudine Ah‐Peng Fabio Attorre H. John B. Birks Paulo A. V. Borges Pedro Cardoso Chang‐Hung Chou Michele De Sanctis Miguel M. de Sequeira Maria C. Duarte Rui B. Elias José María Fernández‐Palacios Rosalina Gabriel Roy E. Gereau Rosemary G. Gillespie Josef Greimler David E. V. Harter Tsurng‐Juhn Huang Severin D. H. Irl Daniel Jeanmonod Anke Jentsch Alistair S. Jump Christoph Kueffer Sandra Nogué Rüdiger Otto Jonathan Price Maria M. Romeiras Dominique Strasberg Tod Stuessy Jens‐Christian Svenning Ole R. Vetaas Carl Beierkuhnlein 《Global Ecology and Biogeography》2016,25(9):1097-1107
154.
Marten Klukkert Jian X. Wu Jukka Rantanen Soenke Rehder Jens M. Carstensen Thomas Rades Claudia S. Leopold 《AAPS PharmSciTech》2016,17(4):958-967
Chemical imaging techniques are beneficial for control of tablet coating layer quality as they provide spectral and spatial information and allow characterization of various types of coating defects. The purpose of this study was to assess the applicability of multispectral UV imaging for assessment of the coating layer quality of tablets. UV images were used to detect, characterize, and localize coating layer defects such as chipped parts, inhomogeneities, and cracks, as well as to evaluate the coating surface texture. Acetylsalicylic acid tablets were prepared on a rotary tablet press and coated with a polyvinyl alcohol-polyethylene glycol graft copolymer using a pan coater. It was demonstrated that the coating intactness can be assessed accurately and fast by UV imaging. The different types of coating defects could be differentiated and localized based on multivariate image analysis and Soft Independent Modeling by Class Analogy applied to the UV images. Tablets with inhomogeneous texture of the coating could be identified and distinguished from those with a homogeneous surface texture. Consequently, UV imaging was shown to be well-suited for monitoring of the tablet coating layer quality. UV imaging is a promising technique for fast quality control of the tablet coating because of the high data acquisition speed and its nondestructive analytical nature. 相似文献
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156.
Has land surface cover in South America been impacted by the loss of most large herbivores following the severe Pleistocene and Early Holocene megafauna extinctions on this continent? Here, we estimate how mean savanna woody biomass may have changed in the Americas following these extinctions by creating an empirical model to understand how large herbivores impact savanna woody biomass. To create this empirical model, we combine a large recently published dataset of savanna woody cover from Lehmann et al. (2014) (n = 2154 plots) with estimates of mammals ranges and weights from the IUCN database. We evaluate how variables such as number of megaherbivores (mammal species ≥ 1000 kg), log10 sum species weights, and total number of mammal species predict changes to woody cover by using both ordinary least squares regression analysis (OLS) and simultaneous auto‐regressive (SAR) analysis to control for spatial autocorrelation. Both number of megaherbivores and log10 sum species weights, which both disproportionately weight for megaherbivores, significantly explained much (~ 5–13%) variance in woody cover, but the third variable weighting all animals equally, did not. We then combined these biotic variables with abiotic variables such as temperature, precipitation, and fire frequency to create a model predicting 36% of the variance of savanna woody cover. We used this model combined with estimated range maps of extinct South American megafauna to estimate that had those South American megafauna not gone extinct, total savanna woody cover in South America could possibly have decreased by ~ 29% and that savannas would likely have been more open like current African savannas. 相似文献
157.
Seminatural grasslands provide habitats for various species and are important for biodiversity conservation. The understanding of the diverse responses of species and traits to different grassland managenient methods is therefore urgently needed. We disentangled the role of grassland management (fertilization and irrigation), vegetation structure (biomass, sward height) and plant quality (protein and fiber content) for Orthoptera communities in lowland hay meadows in Germany. We found vegetation structure to be the most important environmental category in explaining community structure of Orthoptera (species richness, total individuals, fiinctional diversity and species composition). Intensively used meadows (fertilized, irrigated, high plant biomass) were characterized by assemblages with few species, low functional diversity, and low conservation value. Thereby, the relatively moderate fertilizer inputs in our study system of up to -75 kg N/ha/year reduced functional diversity of Orthoptera, while this negative effect of fertilization was not detectable when solely considering taxonomic aspects. We found strong support for a prominent role of plant quality in shaping Orthoptera communities and especially the trait composition. Our findings demonstrate the usefulness of considering both taxonomic and functional comp on ents (functio nal diversity) in biodiversity research and we suggest a stronger involvement of plant quality measures in Orthoptera studies. 相似文献
158.
Laura Cristina Ceafalan Tudor Emanuel Fertig Teodora Cristina Gheorghe Mihail Eugen Hinescu Bogdan Ovidiu Popescu Jens Pahnke Mihaela Gherghiceanu 《Journal of cellular and molecular medicine》2019,23(2):819-827
The blood‐brain barrier (BBB) is essential for a functional neurovascular unit. Most studies focused on the cells forming the BBB, but very few studied the basement membrane (BM) of brain capillaries in ageing. We used transmission electron microscopy and electron tomography to investigate the BM of the BBB in ageing C57BL/6J mice. The thickness of the BM of the BBB from 24‐month‐old mice was double as compared with that of 6‐month‐old mice (107 nm vs 56 nm). The aged BBB showed lipid droplets gathering within the BM which further increased its thickness (up to 572 nm) and altered its structure. The lipids appeared to accumulate toward the glial side of the BM. Electron tomography showed that the lipid‐rich BM regions are located in small pockets formed by the end‐feet of astrocytes. These findings suggest an imbalance of the lipid metabolism and that may precede the structural alteration of the BM. These alterations may favour the accretion of abnormal proteins that lead to neurodegeneration in ageing. These findings warrant further investigation of the BM of brain capillaries and of adjoining cells as potential targets for future therapies. 相似文献
159.
Habacuc Flores‐Moreno Farideh Fazayeli Arindam Banerjee Abhirup Datta Jens Kattge Ethan E. Butler Owen K. Atkin Kirk Wythers Ming Chen Madhur Anand Michael Bahn Chaeho Byun J. Hans C. Cornelissen Joseph Craine Andres Gonzalez‐Melo Wesley N. Hattingh Steven Jansen Nathan J. B. Kraft Koen Kramer Daniel C. Laughlin Vanessa Minden Ülo Niinemets Vladimir Onipchenko Josep Peuelas Nadejda A. Soudzilovskaia Rhiannon L. Dalrymple Peter B. Reich 《Global Ecology and Biogeography》2019,28(12):1806-1826
160.
Anne-Marie Lundsgaard Jacob B. Holm Kim A. Sjøberg Kirstine N. Bojsen-Møller Lene S. Myrmel Even Fjære Benjamin A.H. Jensen Trine S. Nicolaisen Janne R. Hingst Sine L. Hansen Sophia Doll Philip E. Geyer Atul S. Deshmukh Jens J. Holst Lise Madsen Karsten Kristiansen Jørgen F.P. Wojtaszewski Erik A. Richter Bente Kiens 《Cell metabolism》2019,29(1):50-63.e4