全文获取类型
收费全文 | 312篇 |
免费 | 28篇 |
出版年
2024年 | 1篇 |
2023年 | 4篇 |
2022年 | 3篇 |
2021年 | 10篇 |
2020年 | 14篇 |
2019年 | 23篇 |
2018年 | 10篇 |
2017年 | 5篇 |
2016年 | 10篇 |
2015年 | 17篇 |
2014年 | 18篇 |
2013年 | 12篇 |
2012年 | 21篇 |
2011年 | 11篇 |
2010年 | 18篇 |
2009年 | 16篇 |
2008年 | 13篇 |
2007年 | 11篇 |
2006年 | 13篇 |
2005年 | 13篇 |
2004年 | 15篇 |
2003年 | 18篇 |
2002年 | 12篇 |
2001年 | 2篇 |
2000年 | 8篇 |
1999年 | 5篇 |
1998年 | 8篇 |
1997年 | 3篇 |
1991年 | 1篇 |
1990年 | 1篇 |
1989年 | 5篇 |
1988年 | 3篇 |
1987年 | 1篇 |
1986年 | 2篇 |
1985年 | 2篇 |
1984年 | 2篇 |
1983年 | 1篇 |
1982年 | 2篇 |
1979年 | 1篇 |
1977年 | 1篇 |
1975年 | 1篇 |
1974年 | 2篇 |
1973年 | 1篇 |
排序方式: 共有340条查询结果,搜索用时 46 毫秒
101.
102.
Atena Soleimani Fereshteh Asgharzadeh Farzad Rahmani Amir Avan Saeedeh Mehraban Maryam Fakhraei Mohammad Hassan Arjmand Maryam Moradi Binabaj Mohammad Reza Parizadeh Gordon A. Ferns Mikhail Ryzhikov Amir Reza Afshari Jalal Naghinezhad Sayyed Hadi Sayyed-Hosseinian Majid Khazaei Seyed Mahdi Hassanian 《Journal of cellular physiology》2020,235(2):1349-1357
Here, we have investigated the therapeutic potency of EW-7197, a transforming growth factor-β type I receptor kinase inhibitor, against postsurgical adhesion band formation. Our results showed that this pharmacological inhibitor prevented the frequency and the stability of adhesion bands in mice model. We have also shown that downregulation of proinflammatory cytokines, reduce submucosal edema, attenuation of proinflammatory cell infiltration, inhibition of oxidative stress, decrease in excessive collagen deposition, and suppression of profibrotic genes at the site of surgery are some of the mechanisms by which EW-7197 elicits its protective responses against adhesion band formation. These results clearly suggest that EW-7197 has novel therapeutic properties against postsurgical adhesion band formation with clinically translational potential of inhibiting key pathological responses of inflammation and fibrosis in postsurgery patients. 相似文献
103.
104.
A gene encoding the xylanase from Bacillus subtilis strain R5 containing the native signal sequence was cloned and expressed in Escherichia coli. The heterologous expression of the gene resulted in the production of the recombinant protein in the cytoplasm as well as
its secretion into the culture medium. The xylanase activity in the culture medium increased with time after induction up
to 90% of the total activity in 14 h. Molecular mass and N-terminal amino acid sequence determinations of the purified recombinant
xylanase revealed that the native signal peptide was cleaved off by E. coli signal peptidases between Ala28 and Ala29. 相似文献
105.
106.
Li Hao Guo Yanliang Cui Qi Zhang Zixing Yan Xing Ahammed Golam Jalal Yang Xiaozhen Yang Jianqiang Wei Chunhua Zhang Xian 《Journal of Plant Growth Regulation》2020,39(4):1441-1450
Journal of Plant Growth Regulation - As the outermost hydrophobic layer, cuticular waxes serve as an essential waterproof barrier to protect plants from desiccation, but the mechanism of wax... 相似文献
107.
Plants were grown in field conditions in the wide area under normal water supply and severe water deficit. Two wheat (Triticum aestivum L.) genotypes contrasting by architectonics and differing in drought-resistance were used: Giymatli-2/17, short stature, with broad and drooping leaves, drought-sensitive, and Azamatli-95, short stature, with vertically oriented small leaves, drought-tolerant). It was found out that Giymatli-2/17 was characterized by relatively low content of Chl a-protein of PS I (CP I) and β-subunit of ATP-synthase complex, the high content of proteins in the 33-30.5 kDa region and LHC polypeptides (28-24.5 kDa), the intensive fluorescence at 740 nm and more high photochemical activity of PS II under normal irrigation compared with Azamatli-95. However, the content of CP I (Mr 115 kDa) and apoprotein of P700 with Mr 63 kDa insignificantly increases in the drought-resistant genotype Azamatli-95 under extreme water supply condition while their content decreases in drought-sensitive cv Giymatli-2/17. Intensity of synthesis α- and β-subunits of CF1 (55 and 53.5 kDa) also decreases in Giymatli-2/17. The levels of the core antenna polypeptides of FS II with Mr 46 and 44.5 kDa (CP47 and CP43) remains stable both in normal, and stressful conditions. At the same time the significant reduction is observed in the content of polypeptides in the 33-30.5 kDa region in the more sensitive genotype Giymatli-2/17. There is an increase in the LHC II polypeptides level in tolerant genotype Azamatli-95 in contrast to Giymatli-2/17 (where the content of these subunits is observed decreasing). The intensity of short wavelength peaks at 687 and 695 nm sharply increases in the fluorescence spectra (77 K) of chloroplasts from sensitive genotype Giymatli-2/17 under water deficiency and there is a stimulation of the ratio of fluorescence band intensity F687/F740. After exposure to drought, cv Giymatli-2/17 shows a larger reduction in the actual PS II photochemical efficiency of chloroplasts than cv Azamatli-95. 相似文献
108.
Plants were grown in field conditions in the wide area under normal water supply and severe water deficit. Two wheat (Triticum aestivum L.) genotypes contrasting by architectonics and differing in drought-resistance were used: Giymatli-2/17, short stature, with broad and drooping leaves, drought-sensitive, and Azamatli-95, short stature, with vertically oriented small leaves, drought-tolerant). It was found out that Giymatli-2/17 was characterized by relatively low content of Chl a-protein of PS I (CP I) and beta-subunit of ATP-synthase complex, the high content of proteins in the 33-30.5 kDa region and LHC polypeptides (28-24.5 kDa), the intensive fluorescence at 740 nm and more high photochemical activity of PS II under normal irrigation compared with Azamatli-95. However, the content of CP I (M(r) 115 kDa) and apoprotein of P700 with M(r) 63 kDa insignificantly increases in the drought-resistant genotype Azamatli-95 under extreme water supply condition while their content decreases in drought-sensitive cv Giymatli-2/17. Intensity of synthesis alpha- and beta-subunits of CF(1) (55 and 53.5 kDa) also decreases in Giymatli-2/17. The levels of the core antenna polypeptides of FS II with M(r) 46 and 44.5 kDa (CP47 and CP43) remains stable both in normal, and stressful conditions. At the same time the significant reduction is observed in the content of polypeptides in the 33-30.5 kDa region in the more sensitive genotype Giymatli-2/17. There is an increase in the LHC II polypeptides level in tolerant genotype Azamatli-95 in contrast to Giymatli-2/17 (where the content of these subunits is observed decreasing). The intensity of short wavelength peaks at 687 and 695 nm sharply increases in the fluorescence spectra (77 K) of chloroplasts from sensitive genotype Giymatli-2/17 under water deficiency and there is a stimulation of the ratio of fluorescence band intensity F687/F740. After exposure to drought, cv Giymatli-2/17 shows a larger reduction in the actual PS II photochemical efficiency of chloroplasts than cv Azamatli-95. 相似文献
109.
Elizabeth E. Palmer Seungbeom Hong Fatema Al Zahrani Mais O. Hashem Fajr A. Aleisa Heba M. Jalal Ahmed Tejaswi Kandula Rebecca Macintosh Andre E. Minoche Clare Puttick Velimir Gayevskiy Alexander P. Drew Mark J. Cowley Marcel Dinger Jill A. Rosenfeld Rui Xiao Megan T. Cho Suliat F. Yakubu Stefan T. Arold 《American journal of human genetics》2019,104(3):542-552
110.