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61.
L V Filev V G Popov I V Volchek S F Enokhin Iu V Medvedev 《Zhurnal mikrobiologii, epidemiologii, i immunobiologii》1985,(11):72-76
The influence of interlok, biotop and remantadine on the functional activity of monocytes was determined with the use of the NBT test permitting the quantitative evaluation of this characteristic. In this study interlok was found to give promising results in the treatment of acute viral hepatitis, due both to its antiviral action and to the stimulation of the functional activity of monocytes. biotop proved to render a sharply pronounced stimulating effect on the functional activity of monocytes, thus enhancing antiviral resistance. Remantadine suppressed the functional activity of monocytes and increased their lesion by the virus, thus creating favorable conditions for virus persistence in monocytes. 相似文献
62.
G Iu Miterev G F Burova M S Puzhitskaia S V Danilevich T I Bulycheva 《Biulleten' eksperimental'no? biologii i meditsiny》1987,103(6):710-712
Two hybridomas secreting mouse cytotoxic monoclonal antibodies to in vivo and in vitro activated human T-lymphocyte and neutrophil surface membrane antigenic determinants have been produced. One of these monoclonal antibodies (Ta/H-2) appeared to be also specifically reactive to blast cells in the majority of non-T-non-B and T acute lymphoblastic leukemia patients. 相似文献
63.
Tiron as a spin-trap for superoxide radicals produced by the respiratory chain of submitochondrial particles 总被引:1,自引:0,他引:1
I V Grigolava M Iu Ksenzenko A A Konstantinob A N Tikhonov T M Kerimov 《Biokhimii?a (Moscow, Russia)》1980,45(1):75-82
Tiron can be used as a spin-trap for O2 radicals generated by the respiratory chain of submitochondrial particles (SMP). Using this sensitive method, it was shown that the O2 (radical) production by the succinate-oxidizing SMP can be reduced by antimycin or 4-nonyl-2-hydroxyquinoline-N-oxide, the effects of both antibiotics being abolished and prevented by cyanide. It is suggested tht the O2 radicals are produced due to autooxidation of ubisemiquinone which is formed as an intermediate upon one-electron oxidation of CoQH2 by cytochrome c1. The effects of antimycin, 2-nonyl-4-hydroxyquinoline-N-oxide and cyanide on the O2 (radical) generation correlate with the effects of these inhibitors on a steady-state concentration of ubisemiquinone predicted by the Mitchell's Q-cycle hypothesis. 相似文献
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It has been shown that the resistance of muscular larvae of Trichinella spiralis to the effect of low temperatures depends on the conditions of freezing and composition of media possessing cryoprotective properties. It has been established that under optimal conditions (medium of microenvironment, conditions of freezing) during the storage in liquid nitrogen muscular larvae of T. spiralis preserve 50 to 60% of their resistance by the character of mobility and 11 to 15% by their capacity for reproduction. The question of creation of low-temperature bank for Trichinella is discussed. 相似文献
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Structural changes of the cytoskeleton of the frog urinary bladder granular cells were examined during low and high water permeability of the epithelium. A tight connection of the microfilaments and microtubules with vacuolar membranes and a great increase in the number of microtubules during a stimulated water flow was shown using different electron microscopic methods. Two populations of microtubules were discovered, respectively, with different diameter and different rate of stability. It is suggested that the thicker microtubules while interacting with actin microfilaments through associated electron dense globules may fulfil the transport function in the cell. 相似文献
69.
I M Badalova B N Mishan'kin I Iu Suchkov 《Zhurnal mikrobiologii, epidemiologii, i immunobiologii》1987,(5):24-28
In two different strains of cholera vibrios two recA-dependent plasmids, pVib I (1.9-2.2 Md) and pVib II (5.2-5.8 Md), have been detected. These plasmids determine the synthesis of vibriocin, coagulase and fibrinolysin, which has been established by the cotransformation of the DNA of plasmids pVib I and pBR322 and by the transfer mobilization with the use of plasmid RP4. 相似文献
70.