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71.
Shtyrlin Valery G. Borissenok Valery A. Serov Nikita Yu. Simakov Vladimir G. Bragunets Vyacheslav A. Trunin Ivan R. Tereshkina Irina A. Koshkin Sergey A. Bukharov Mikhail S. Gilyazetdinov Edward M. Shestakov Evgeny E. Sirotkina Anna G. Zakharov Alexey V. 《Origins of life and evolution of the biosphere》2019,49(1-2):1-18
Origins of Life and Evolution of Biospheres - Syntheses under shock in nitrogen bubbled samples of the water – formamide – bicarbonate – sodium hydroxide system at... 相似文献
72.
Boris R. Krasnov Georgy S. Shenbrot Luther van der Mescht Elizabeth M. Warburton Irina S. Khokhlova 《Ecography》2019,42(5):1000-1011
We studied patterns of phylogenetic and compositional diversity of fleas parasitic on small mammals and asked whether these patterns are affected by environmental variation or evolutionary/historical processes. We considered environmental variation via both off‐host (air temperature, precipitation, the amount of green vegetation, latitude) and host‐associated (phylogenetic and species composition) environments. The indicators of evolutionary/historical processes were phylogenetic and compositional uniqueness estimated via phylogenetic or compositional, respectively, β‐diversity of either fleas or hosts. We found that phylogenetic uniqueness of flea assemblages was the main predictor of their phylogenetic diversity in all realms. In addition, host phylogenetic diversity and uniqueness played also some role in the Palearctic, whereas the effect of the off‐host environment was either extremely weak or absent. Compositional diversity of fleas was consistently affected by compositional diversity of hosts in all realms except the Neotropics. The effect of the off‐host environment on compositional flea diversity was substantial in all realms except the Palearctic. No effect of latitude on either metric of flea diversity was found. We conclude that phylogenetic diversity of fleas is driven mainly by evolutionary/historical processes, whereas drivers of their compositional diversity are associated with current ecological conditions. 相似文献
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74.
Constantin Munteanu Mariana Rotariu Marius-Alexandru Turnea Aurelian Anghelescu Irina Albadi Gabriela Dogaru Sînziana Calina Siliteanu Elena Valentina Ionescu Florentina Carmen Firan Anca Mirela Ionescu Carmen Oprea Gelu Onose 《Current issues in molecular biology》2022,44(8):3378
Diabetes mellitus (DM) is a frequent medical problem, affecting more than 4% of the population in most countries. In the context of diabetes, the vascular endothelium can play a crucial pathophysiological role. If a healthy endothelium—which is a dynamic endocrine organ with autocrine and paracrine activity—regulates vascular tone and permeability and assures a proper balance between coagulation and fibrinolysis, and vasodilation and vasoconstriction, then, in contrast, a dysfunctional endothelium has received increasing attention as a potential contributor to the pathogenesis of vascular disease in diabetes. Hyperglycemia is indicated to be the major causative factor in the development of endothelial dysfunction. Furthermore, many shreds of evidence suggest that the progression of insulin resistance in type 2 diabetes is parallel to the advancement of endothelial dysfunction in atherosclerosis. To present the state-of-the-art data regarding endothelial dysfunction in diabetic micro- and macroangiopathy, we constructed this literature review based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). We interrogated five medical databases: Elsevier, PubMed, PMC, PEDro, and ISI Web of Science. 相似文献
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76.
Belokopytova Irina I. Kondaurova Elena M. Kulikova Elizabeth A. Ilchibaeva Tatiana V. Naumenko Vladimir S. Popova Nina K. 《Biochemistry. Biokhimii?a》2022,87(10):1206-1218
Biochemistry (Moscow) - The mechanisms of autism are of extreme interest due to the high prevalence of this disorder in the human population. In this regard, special attention is given to the... 相似文献
77.
Brandstaetter Christian Fricko Nora Rahimi Mohammad J. Fellner Johann Ecker-Lala Wolfgang Druzhinina Irina S. 《Biodegradation》2022,33(1):71-85
Biodegradation - Biological waste degradation is the main driving factor for landfill emissions. In a 2-year laboratory experiment simulating different landfill in-situ aeration scenarios, the... 相似文献
78.
Studneva Irina M. Veselova Oksana M. Dobrokhotov Igor V. Serebryakova Larisa I. Palkeeva Marina E. Molokoedov Alexander S. Azmuko Andrey A. Ovchinnikov Michael V. Sidorova Maria V. Pisarenko Oleg I. 《Biochemistry. Biokhimii?a》2022,87(4):346-355
Biochemistry (Moscow) - Neuropeptide galanin and its N-terminal fragments reduce the generation of reactive oxygen species and normalize metabolic and antioxidant states of myocardium in... 相似文献
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80.
Sergiev PV Lesnyak DV Burakovsky DE Svetlov M Kolb VA Serebryakova MV Demina IA Govorun VM Dontsova OA Bogdanov AA 《Journal of molecular biology》2012,416(5):656-667
Catalysis of peptide bond formation in the peptidyl transferase center is a major enzymatic activity of the ribosome. Mutations limiting peptidyl transferase activity are mostly lethal. However, cellular processes triggered by peptidyl transferase deficiency in the bacterial cell are largely unknown. Here we report a study of the lethal G2061C mutant of Escherichia coli 23S ribosomal RNA (rRNA). The G2061C mutation completely impaired the puromycin reaction and abolished formation of the active firefly luciferase in an in vitro translation system, while poly(U)- and short synthetic mRNA-directed peptidyl transferase reaction with aminoacylated tRNAs in vitro was seemingly unaffected. Study of the cellular proteome upon expression of the 23S rRNA gene carrying the G2061C mutation compared to cells expressing wild-type 23S rRNA gene revealed substantial differences. Most of the observed effects in the mutant were associated with reduced expression of stress response proteins and particularly proteins associated with the ppGpp-mediated stringent response. 相似文献