全文获取类型
收费全文 | 623篇 |
免费 | 28篇 |
国内免费 | 1篇 |
出版年
2024年 | 2篇 |
2023年 | 16篇 |
2022年 | 24篇 |
2021年 | 52篇 |
2020年 | 19篇 |
2019年 | 24篇 |
2018年 | 25篇 |
2017年 | 17篇 |
2016年 | 28篇 |
2015年 | 35篇 |
2014年 | 39篇 |
2013年 | 44篇 |
2012年 | 57篇 |
2011年 | 33篇 |
2010年 | 20篇 |
2009年 | 23篇 |
2008年 | 31篇 |
2007年 | 24篇 |
2006年 | 28篇 |
2005年 | 23篇 |
2004年 | 26篇 |
2003年 | 21篇 |
2002年 | 17篇 |
2001年 | 6篇 |
2000年 | 2篇 |
1998年 | 1篇 |
1996年 | 1篇 |
1995年 | 1篇 |
1994年 | 1篇 |
1993年 | 1篇 |
1987年 | 1篇 |
1986年 | 1篇 |
1985年 | 1篇 |
1984年 | 1篇 |
1982年 | 1篇 |
1978年 | 2篇 |
1976年 | 1篇 |
1973年 | 1篇 |
1971年 | 1篇 |
1968年 | 1篇 |
排序方式: 共有652条查询结果,搜索用时 62 毫秒
651.
Junaid ur Rahim Arfan Khalid Sudha Shankar Irfan Qasam Govind Yadav Rajkishor Rai 《Journal of peptide science》2023,29(7):e3485
The present work describes the synthesis, characterization, and wound healing properties of α/γ hybrid peptides: Boc-Phe-γ4-Phe-Val-OMe ( S1 ), Boc-DPhe-γ4-Phe-Val-OMe ( S2 ), Boc-Ala-γ4-Phe-Val-OMe ( S3 ), Boc-DAla-γ4-Phe-Val-OMe ( S4 ), Boc-Leu-γ4-Phe-Val-OMe ( S5 ), and Boc-DLeu-γ4-Phe-Val-OMe ( S6 ). Peptides S1–S6 were screened against human keratinocytes (HaCaT) and RAW 264.7 cells. Among all, S1 - and S2 -treated cells exhibited high cell viability; S1 and S2 induced keratinocyte migration and inhibited the production of the cytokines IL-6 and TNF-α. In vivo results demonstrated that the hybrid peptides S1 and S2 accelerate wound healing in Wistar rats with 83% and 88% at 50 μg/ml, and 74% and 76% at 25 μg/ml, respectively. 相似文献
652.
The main objectives of the study were to produce inulinase from carob extract by Aspergillus niger A42 (ATCC 204447) and to model the inulinase fermentation in the optimum carob extract-based medium. In the study, carob extract was used as a novel and renewable carbon source in the production of A. niger inulinase. For medium optimization, eight different variables including initial sugar concentration (°Bx), (NH4)2HPO4, MgSO4.7H2O, KH2PO4, NH4NO3, yeast extract, peptone, and ZnSO4.7H2O were employed. After fermentations, optimum medium composition contained 1% yeast extract in 5°Bx carob extract. As a result of the fermentation, the maximum inulinase activity, maximum invertase-type activity, I/S ratio, maximum inulinase- and invertase-type activity rates, maximum sugar consumption rate, and sugar utilization yield were 1507.03 U/ml, 1552.86 U/ml, 0.97, 175.82 and 323.76 U/ml/day, 13.26 g/L/day, and 98.52%, respectively. Regarding mathematical modeling, the actual inulinase production and sugar consumption data were successfully predicted by Baranyi and Cone models based on the model evaluation and validation results and the predicted kinetic values, respectively. Consequently, this was the first report in which carob extract was used in the production of inulinase as a carbon source. Additionally, the best-selected models can serve as universal equations in modeling the inulinase production and sugar consumption in shake flask fermentation with carob extract medium. 相似文献