排序方式: 共有169条查询结果,搜索用时 15 毫秒
31.
Saadat M Khalili M Nasiri M Rajaei M Omidvari S Saadat I 《Biochemical and biophysical research communications》2012,419(1):117-119
The main aim of the present study was to investigate the association between several genetic polymorphisms (in glutathione S-transferase members and DNA repair genes) and clinical response to chemotherapy in locally advanced breast cancer. A sequential series of 101 patients were prospectively included in this study. Clinical assessment of treatment was accomplished by comparing initial tumor size with preoperative tumor size using revised RECIST guideline (version 1.1). Clinical response was regarded as a response or no response. There was no difference between non-responders and responders for the prevalence of genotypes of the study polymorphisms. 相似文献
32.
Tabatabaei Seyedeh Narjes Abdoli Asghar Hashemzadeh Segherloo Iraj Normandeau Eric Ahmadzadeh Faraham Nejat Farshad Bernatchez Louis 《Hydrobiologia》2020,847(16):3339-3353
Hydrobiologia - Many populations of Caspian Sea trout (Salmo caspius)—a nationally endangered species in Iran—have been extirpated or depleted due to anthropogenic impacts. The Lar... 相似文献
33.
Samira Rezvani Borujeni Kazem Khavazi Ahmad Asgharzadeh Iraj Rezvani Borujeni 《International journal of phytoremediation》2018,20(5):476-482
Oil presence in soil, as a stressor, reduces phytoremediation efficiency through an increase in the plant stress ethylene. Bacterial 1-aminocyclopropane-1-carboxylic acid (ACC) deaminase, as a plant stress ethylene reducer, was employed to increase oil phytoremediation efficiency. For this purpose, the ability of ACC deaminase-producing Pseudomonas strains to grow in oil-polluted culture media and withstand various concentrations of oil and also their ability to reduce plant stress ethylene and enhance some growth characteristics of maize and finally their effects on increasing phytoremediation efficiency of poly aromatic hydrocarbons (PAHs) in soil were investigated. Based on the results, of tested strains just P9 and P12 were able to perform oil degradation. Increasing oil concentration from 0 to 10% augmented these two strains population, 15.7% and 12.9%, respectively. The maximum increase in maize growth was observed in presence of P12 strain. Results of high-performance liquid chromatography (HPLC) revealed that PAHs phytoremediation efficiency was higher for inoculated seeds than uninoculated. The highest plant growth and PAHs removal percentage (74.9%) from oil-polluted soil was observed in maize inoculated with P12. These results indicate the significance of ACC deaminase producing bacteria in alleviation of plant stress ethylene in oil-polluted soils and increasing phytoremediation efficiency of such soils. 相似文献
34.
Quercetin: A functional dietary flavonoid with potential chemo‐preventive properties in colorectal cancer 下载免费PDF全文
35.
The purpose of the present investigation was to produce erythritol by Yarrowia lipolytica mutant without any by-products. Mutants of Y. lipolytica were generated by ultra-violet for enhancing erythrose reductase (ER) activity and erythritol production. The mutants showing the highest ER activity were screened by triphenyl tetrazolium chloride agar plate assay. Productivity of samples was analyzed by thin-layer chromatography and high-performance liquid chromatography equipped with the refractive index detector. One of the mutants named as mutant 49 gave maximum erythritol production without any other by-products (particularly glycerol). Erythritol production and specific ER activity in mutant 49 increased to 1.65 and 1.47 times, respectively, in comparison with wild-type strain. The ER gene of wild and mutant strains was sequenced and analyzed. A general comparison of wild and mutant gene sequences showed the replacement of Asp270 with Glu270 in ER protein. In order to enhance erythritol production, we used a three component-three level-one response Box–Behnken of response surface methodology model. The optimum medium composition for erythritol production was found to be (g/l) glucose 279.49, ammonium sulfate 9.28, and pH 5.41 with 39.76 erythritol production. 相似文献
36.
Chemical investigation of insect antifeedants from the bitter tasting leaves of Vernonia amygdalina by the application of semi-preparative reversed 相似文献
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38.
Majid Moghadam Shahram Tangestaninejad Valiollah Mirkhani Iraj Mohammadpoor-baltork Narges Sirjanian Somayeh Parand 《Bioorganic & medicinal chemistry》2009,17(9):3394-3398
In this report, highly efficient oxidative decarboxylation of carboxylic acids with sodium periodate catalyzed by a supported manganese(III) porphyrin is described. In the presence of manganese(III) tetra(4-pyridyl)porphyrin supported on cross-linked chloromethylated polystyrene, [Mn(T4PyP)-CMP], as catalyst, carboxylic acids were converted to their corresponding carbonyl compounds via oxidative decarboxylation with sodium periodate using imidazole as axial ligand. The oxidation of anti-inflammatory drugs such Indomethacin and Ibuprofen was carried out successfully and the decarboxylated products were obtained. This catalyst can be reused several times without loss of its catalytic activity in the oxidation reactions. 相似文献
39.
Shu-Biao Wu Iraj Tavassolian Gholamreza Rabiei Peter Hunt Michelle Wirthensohn John P. Gibson Christopher M. Ford Margaret Sedgley 《Molecular genetics and genomics : MGG》2009,282(3):273-281
Peach and almond have been considered as model species for the family Rosaceae and other woody plants. Consequently, mapping
and characterisation of genes in these species has important implications. High-resolution melting (HRM) analysis is a recent
development in the detection of SNPs and other markers, and proved to be an efficient and cost-effective approach. In this
study, we aimed to map genes corresponding to known proteins in other species using the HRM approach. Prunus unigenes were searched and compared with known proteins in the public databases. We developed single-nucleotide polymorphism
(SNP) markers, polymorphic in a mapping population produced from a cross between the cloned cultivars Nonpareil and Lauranne.
A total of 12 SNP-anchored putative genes were genotyped in the population using HRM, and mapped to an existing linkage map.
These genes were mapped on six linkage groups, and the predicted proteins were compared to putative orthologs in other species.
Amongst those genes, four were abiotic stress-responsive genes, which can provide a starting point for construction of an
abiotic resistance map. Two allergy and detoxification related genes, respectively, were also mapped and analysed. Most of
the investigated genes had high similarities to sequences from closely related species such as apricot, apple and other eudicots,
and these are putatively orthologous. In addition, it was shown that HRM can be an effective means of genotyping populations
for the purpose of constructing a linkage map. Our work provides basic genomic information for the 12 genes, which can be
used for further genetic and functional studies. 相似文献
40.
Shadab Gharaati Shahram Tangestaninejad Valiollah Mirkhani Iraj Mohammadpoor-Baltork Farshid Kosari 《Inorganica chimica acta》2010,363(9):1995-646
An efficient and selective method for methoxymethylation of alcohols and phenols with formaldehyde dimethyl acetal (FDMA) catalyzed by electron deficient tin(IV)tetraphenylporphyrinato trifluoromethanesulfonate, [SnIV(TPP)(OTf)2], is reported. A variety of primary, secondary and tertiary alcohols as well as phenols were converted to their corresponding methoxymethyl ethers with FDMA in the presence of a high-valent tin(IV) porphyrin. This catalyst can be used for selective methoxymethylation of primary, secondary and tertiary alcohols in the presence of phenols or tertiary alcohols. The present method offers several advantages such as short reaction times, high yields, simple procedure, selectivity and applicability for both alcohols and phenols. 相似文献